All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 337360 of 943 models

  • STACK

    142115
    Arc Institute +1 otherJanuary 9, 2026foundation_modelin_context_learningperturbation_prediction+4

    Single-cell foundation model using tabular attention over context cells to predict responses to arbitrary perturbations without fine-tuning.

    Single-cell
    33Openness
  • SurfFlow

    Stanford UniversityJanuary 8, 2026de_novo_designflow_matchinggenerative+5

    Flow-matching model for therapeutic peptide design that co-designs sequence, structure, and molecular surface to disrupt protein-protein interactions.

    ProteinSmall molecule
    18Openness
  • CMAP

    Amazon Web ServicesJanuary 7, 2026antibodyantibody_developabilityin_context_learning+4

    Antibody developability predictor pairing text and protein language models, using in-context learning to fit new assays without retraining.

    ProteinLanguage model
    4Openness
  • DNAChunker

    1
    KAIST +1 otherJanuary 6, 2026dnafunctional_genomicsgenomics+4

    Masked DNA language model with a learnable, adaptive tokenizer that produces context-dependent, variable-length segments instead of fixed k-mers.

    DNA & Gene
    23Openness
  • BiomeGPT

    1
    Massachusetts General HospitalJanuary 5, 2026biomarker_discoverydisease_classificationfoundation_model+6

    Gut microbiome foundation model pretrained on human shotgun metagenomes, learning species-level taxonomic representations for disease prediction.

    DNA & GeneLanguage model
    8Openness
  • MetagenBERT

    MetagenBERT AuthorsJanuary 5, 2026bertdnaembeddings+5

    Annotation-free metagenome embedding pipeline that encodes raw DNA reads with genomic language models and pools them via FAISS k-means clustering.

    DNA & Gene
    22Openness
  • NetMedGPT

    2
    University of Hamburg +1 otherJanuary 4, 2026drug_discoverydrug_repurposingfoundation_model+6

    Transformer foundation model pretrained on a biomedical knowledge graph for zero-shot drug repurposing, target, and adverse-effect prediction.

    Language modelSmall molecule
    24Openness
  • GEMGen

    2
    Westlake University +1 otherJanuary 3, 2026de_novo_designdrug_discoverygenerative+5

    Generative language model for phenotype-driven drug discovery, proposing small-molecule structures from up- and down-regulated gene signatures.

    Small moleculeSingle-cell
    9Openness
  • Nobuyuki OtaJanuary 3, 2026cell_biologygene_expressiongenomics+4

    Multimodal architecture coupling pretrained DNA, RNA, and protein language models with directional cross-attention into one Virtual Cell Embedding.

    DNA & GeneRNAProtein
    22Openness
  • PeptiVerse

    11
    University of Pennsylvania +1 otherJanuary 3, 2026binding_affinity_predictiondrug_discoverygradient_boosting+4

    Peptide developability predictor scoring solubility, permeability, toxicity, and binding from amino-acid sequences or chemically modified SMILES.

    ProteinSmall molecule
    81Openness
  • Merlin

    452517.3K
    Stanford UniversityJanuary 1, 2026cnncontrastive_learningct+8

    3D vision-language foundation model for abdominal CT, pretrained on scans, radiology reports, and EHR codes for zero-shot interpretation.

    ImagingLanguage model
    54Openness
  • SpatialDINO

    193
    Harvard Medical SchoolDecember 31, 2025cell_biologyfoundation_modelmicroscopy+5

    Native 3D vision transformer self-supervised on unlabeled fluorescence microscopy volumes, segmenting subcellular structures without voxel labels.

    Imaging
    8Openness
  • MicroGenomer

    10
    BGI ResearchDecember 29, 2025embeddingsfoundation_modelgenomics+6

    470M-parameter microbial genome foundation model trained on 234.5B base pairs for multi-scale genomic representation and trait prediction.

    DNA & Gene
    44Openness
  • OmniCell

    1
    BGI ResearchDecember 29, 2025cell_type_annotationfoundation_modelgene_expression+6

    Transcriptomic foundation model pretrained on 67M single-cell and spatial profiles, modeling gene expression and inter-cellular dependencies.

    Single-cellSpatial omics
    9Openness
  • HELM-BERT

    141.4K
    Kyoto UniversityDecember 29, 2025debertalanguage_modelmacrocycles+7

    Peptide language model trained on HELM notation, a DeBERTa encoder for property prediction on macrocyclic and non-canonical medium-sized peptides.

    Small molecule
    80Openness
  • GenoME

    1
    Changping Laboratory +1 otherDecember 28, 2025chromatinepigenomicsfoundation_model+8

    Mixture-of-Experts generative model turning DNA sequence plus cell-type ATAC-seq into unified epigenomic, transcriptomic, and 3D chromatin profiles.

    DNA & GeneSingle-cell
    8Openness
  • Baylor College of MedicineDecember 25, 2025cancerfoundation_modelligand_target_inference+7

    Spatially aware transcriptomic foundation models for cancer, pairing 50um-Local and 250um-Extended views of spot-resolution spatial transcriptomes.

    Spatial omics
    12Openness
  • MAGNET

    152
    Huazhong University of Science and TechnologyDecember 25, 2025denoisingfluorescence_microscopyfoundation_model+7

    Microscopy image restoration foundation model unifying 8 tasks across 5 modalities and 2D/3D data, with zero-shot inference on unseen systems.

    Imaging
    7Openness
  • Kitasato University +2 othersDecember 24, 2025codoncodon_optimizationfoundation_model+7

    GPT-style generative language model for mRNA coding sequences, pretrained across bacteria, eukaryotes, and archaea for de novo CDS design.

    RNA
    39Openness
  • FOCUS

    University of CambridgeDecember 23, 2025diffusionfoundation_modelgene_expression_imputation+8

    Generative foundation model that imputes genes and denoises spatial transcriptomics, conditioned on H&E histology, scRNA-seq, and spatial priors.

    Spatial omicsPathologySingle-cell
    4Openness
  • RFdiffusion3

    90764
    Institute for Protein DesignDecember 22, 2025all_atomde_novo_designdiffusion+4

    All-atom protein design diffusion model conditioned on ligands, nucleic acids, and other non-protein atoms, supporting enzyme and DNA binder design.

    Protein
    80Openness
  • InstaDeep +4 othersDecember 22, 2025de_novo_designdnafoundation_model+5

    Multi-species genomics foundation model spanning representation learning, functional-track prediction, and sequence generation at 1 Mb context.

    DNA & Gene
    25Openness
  • ProFam

    58
    University College London +1 otherDecember 21, 2025de_novo_designgenerativelanguage_model+5

    Protein-family language model trained on unaligned homolog sets for zero-shot variant fitness prediction and design. ProFam-1 holds 251M parameters.

    Protein
    86Openness
  • Helix

    36
    Shape TherapeuticsDecember 20, 2025a_to_i_editingguide_rna_designknowledge_distillation+4

    Structure-aware transformer that makes zero-shot, per-adenosine predictions of ADAR-mediated A-to-I RNA editing to guide therapeutic guide-RNA design.

    RNA
    4Openness