A research university in Jerusalem, Israel, spanning the life sciences, medicine, and computer science, with a computational biology tradition.
Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.
Contrastive dual-encoder model embedding protein domains and peptides in one space to predict domain-peptide binding specificity at proteome scale.
Hebrew University of Jerusalem / University of Haifa / Agricultural Research Organization – Volcani Institute
Released September 12, 2025
Nucleotide language model for short metagenomic reads, assigning taxonomic domain, coding potential, and reading frame from reads down to 100 bp.
Flexible protein-ligand docking and binding affinity prediction from an apo receptor structure and ligand SMILES, using an 8-layer pair transformer.
Hebrew University of Jerusalem / Lawrence Berkeley National Laboratory
Released December 21, 2024
Graph neural network that predicts magnesium ion binding sites on RNA structures, powering SAXS-based validation of RNA solution conformations.
National Cancer Institute / Cedars-Sinai Medical Center / University of Cambridge / The Institute of Cancer Research, London / University of Pennsylvania / University of Sydney / Sungkyunkwan University / University of Maryland, College Park / Medical University of Graz / Tel Aviv University / Hebrew University of Jerusalem
Released October 18, 2024
Spatial transcriptomics prediction from H&E slides, inferring spot-level expression and tumor microenvironment composition in breast cancer.
Protein language model pretrained on UniRef90 with masked language modeling and Gene Ontology annotation prediction, at 16 million parameters.