All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 361384 of 943 models

  • PXDesign

    23623
    ByteDance SeedDecember 17, 2025binder_designde_novo_designdiffusion+4

    De novo protein binder design suite from ByteDance pairing diffusion and hallucination generators with confidence-based filtering of designs.

    Protein
    65Openness
  • HD-Prot

    7113
    The Hong Kong Polytechnic University +2 othersDecember 17, 2025diffusiongenerativeinverse_folding+6

    Multimodal protein language model that adds a continuous-token diffusion head to a discrete pLM, modeling structure without vector quantization.

    Protein
    14Openness
  • M-Optimus

    BioptimusDecember 17, 2025clinical_outcome_predictiondrug_target_identificationfoundation_model+8

    Multimodal foundation model that embeds histology, transcriptomics, and clinical records in one space for patient stratification and target discovery.

    PathologySpatial omicsSingle-cell
    3Openness
  • LG AI ResearchDecember 16, 2025biomarker_predictioncancer_subtypingcontrastive_learning+8

    Pathology foundation model that aligns whole-slide images with genomic, epigenetic, and transcriptomic data for patient-level tumor representations.

    PathologySpatial omics
    14Openness
  • GlycanGT

    3
    Nagoya UniversityDecember 16, 2025foundation_modelglycobiologyglycomics+5

    Graph transformer foundation model for glycans, learning reusable embeddings of branched carbohydrate structures for glycomics prediction tasks.

    Small molecule
    82Openness
  • cfRNA-ICL

    Eigen BioDecember 13, 2025cancer_classificationcell_free_rnaearly_cancer_detection+7

    In-context learning model for cell-free RNA, meta-trained on synthetic tasks from a cfRNA structural causal model for few-shot cancer classification.

    Single-cellRNA
    8Openness
  • OmniNovo

    Fudan University +8 othersDecember 13, 2025de_novo_peptide_sequencingfoundation_modelmass_spectrometry+4

    De novo peptide sequencing transformer that reads modified and unmodified peptides directly from tandem mass spectra without a reference database.

    Protein
    14Openness
  • SynPROTAC

    Sun Yat-sen UniversityDecember 12, 2025de_novo_designdrug_discoverygenerative+3

    Designs synthesizable PROTAC degraders from reaction templates and purchasable building blocks, with reinforcement learning tuning the generator.

    Small molecule
    11Openness
  • Eva

    4
    Enable Medicine +4 othersDecember 12, 2025cell_type_annotationcross_modal_inferencefoundation_model+8

    Tissue imaging foundation model pretrained on matched H&E histology and spatial proteomics for cross-modal inference and zero-shot retrieval.

    PathologySpatial omics
    4Openness
  • vir2vec

    358396
    University of FloridaDecember 12, 2025embeddingsfoundation_modelgenomics+6

    Pan-viral genomic language model producing fixed genome-level embeddings of viral DNA and RNA, reused across classification tasks without retraining.

    DNA & Gene
    53Openness
  • ProteinEBM

    7
    MITDecember 9, 2025conformational_dynamicsconformational_samplingdiffusion+5

    Energy-based model of protein conformational space, turning a diffusion model into a statistical potential for structure ranking and mutation scoring.

    Protein
    8Openness
  • Huazhong University of Science and TechnologyDecember 8, 2025dnafoundation_modelgene_expression+6

    Plant genome foundation model pairing a bidirectional Mamba backbone with sparse Mixture-of-Experts, pretrained on 25.4B nucleotides from 42 species.

    DNA & Gene
    53Openness
  • OMTRA

    67
    University of Pittsburgh +1 otherDecember 4, 2025conformer_generationde_novo_designdrug_discovery+8

    Structure-based drug design model that unifies de novo generation, docking, conformer generation, and pharmacophore conditioning via flow matching.

    Small moleculeProtein
    72Openness
  • Institute for Protein DesignDecember 3, 2025de_novo_designdiffusionenzyme_design+3

    Atom-level diffusion model for de novo enzyme design that scaffolds arbitrary active-site geometries without specifying catalytic residue positions.

    Protein
    69Openness
  • PRIMO

    51
    Harvard University +4 othersDecember 2, 2025deep_mutational_scanningin_context_learningprotein_engineering+4

    Transformer for few-shot protein fitness prediction that combines in-context learning with test-time training to adapt to new proteins and assays.

    Protein
    61Openness
  • PanFoMa

    2
    Shanghai Jiao Tong University +4 othersDecember 2, 2025batch_correctioncancercell_type_annotation+7

    Pan-cancer single-cell foundation model with a hybrid Transformer-Mamba architecture, released with the PanFoMaBench cancer evaluation benchmark.

    Single-cell
    13Openness
  • ISTS

    New York UniversityDecember 2, 2025autoencoderbertcancer_classification+9

    Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.

    Single-cellDNA & Gene
    20Openness
  • scMOBA

    11
    Chinese Academy of Sciences +1 otherDecember 2, 2025cell_biologycell_type_annotationdata_integration+5

    Conversational single-cell and spatial multi-omics brain foundation model, with zero-shot cell annotation and disease prediction across species.

    Single-cellLanguage model
    5Openness
  • TriFlow

    9
    University of Chicago +1 otherDecember 2, 2025de_novo_designflow_matchinggenerative+4

    Structure-conditioned protein sequence design, pairing a three-track architecture with discrete flow matching for fast, few-step inverse folding.

    Protein
    69Openness
  • CLEF

    554
    Nokia Bell LabsDecember 1, 2025cardiovascular_risk_predictioncnncontrastive_learning+5

    Single-lead ECG foundation model pretrained on 12-lead recordings, weighting contrastive pairs by clinical risk for cardiovascular risk prediction.

    Biosignals
    62Openness
  • gRNAde

    3098617
    MRC Laboratory of Molecular Biology +1 otherDecember 1, 2025de_novo_designgenerativegraph_neural_network+5

    RNA inverse-folding model that generates sequences predicted to fold into a target 3D backbone, capturing non-canonical pairs and tertiary motifs.

    RNA
    98Openness
  • Tongji University +1 otherNovember 28, 2025cell_type_annotationfoundation_modelgene_expression+6

    Single-cell foundation model adapting LLaMA-3.1-8B with LoRA, recasting transcriptomes and protein interaction networks as natural-language Q&A pairs.

    Single-cellRNA
    55Openness
  • RadDiff

    Nanjing UniversityNovember 28, 2025diffusiongenerativegraph_neural_network+3

    Retrieval-augmented diffusion model for protein inverse folding that conditions sequence generation on profiles from structurally similar homologs.

    Protein
    27Openness
  • TEA

    2423.8K
    Biozentrum +2 othersNovember 27, 2025contrastive_learninghomology_detectionproteomics+4

    Protein sequence encoder that maps ESM2 embeddings to a learned 20-letter alphabet for structure-quality remote homology detection at MMseqs2 speed.

    Protein
    86Openness