Hunter College, CUNY

Molecule generation conditioned on single-cell transcriptomes, designing cell-type-specific compounds that revert diseased cell states.

Signed heterogeneous graph foundation model over the SIGMA-KG knowledge graph, predicting drug mode of action and drug-drug interactions zero-shot.

Inverse molecular design conditioned on transcriptomics, generating small molecules intended to revert a diseased cell to a healthy expression state.