All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 97120 of 203 filtered models

  • NeuroVFM

    554654
    University of Michigan +1 otherNovember 23, 2025ctfoundation_modeljoint_embedding_predictive_architecture+8

    Generalist neuroimaging vision foundation model pretrained on 5.24M clinical MRI and CT volumes for radiologic diagnosis and report generation.

    Imaging
    57Openness
  • SIGMMA

    1
    Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7

    Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.

    PathologySpatial omics
    20Openness
  • E1

    1131115.5K
    ProfluentNovember 13, 2025contact_predictionfoundation_modelproteomics+6

    Retrieval-augmented protein encoders that fuse homologous sequences into a single-pass transformer for variant effect and contact prediction.

    Protein
    47Openness
  • CryoSiam

    201
    European Molecular Biology LaboratoryNovember 12, 2025convolutional_neural_networkcryo_etdenoising+8

    Self-supervised Siamese network for cryo-electron tomography, enabling zero-shot denoising, segmentation, and macromolecule detection in tomograms.

    Imaging
    64Openness
  • JWTH

    1
    Technical University of MunichNovember 7, 2025biomarker_detectioncancerfoundation_model+4

    Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.

    Pathology
    5Openness
  • University of VirginiaNovember 4, 2025batch_correctioncell_type_annotationchromatin+7

    Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.

    Single-cellDNA & Gene
    32Openness
  • Boston UniversityOctober 31, 2025antibodybinding_affinity_predictionlanguage_model+4

    Paired heavy/light antibody language model fine-tuning ESM-2 and ESM-C with CDR-preferential masking for zero-shot binding affinity embeddings.

    Protein
    8Openness
  • LSM-MS2

    Matterworks, Inc.October 30, 2025compound_annotationdisease_classificationembeddings+7

    Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.

    MetabolomicsSmall molecule
    4Openness
  • Harvard Medical SchoolOctober 27, 2025embeddingsrepresentation_learningsiamese_network+1

    Siamese protein language model whose embedding distances approximate TM-score and lDDT, enabling alignment-free protein structure comparison.

    Protein
    5Openness
  • MetaboFM

    2
    Georgia Institute of TechnologyOctober 23, 2025classificationfoundation_modelmass_spectrometry_imaging+6

    Vision Transformer foundation model for spatial metabolomics, pretrained on ~4,000 curated METASPACE mass spectrometry imaging datasets.

    MetabolomicsSpatial omicsImaging
    10Openness
  • PairMixer

    334
    Genesis Therapeutics +1 otherOctober 21, 2025molecular_dockingprotein_designrepresentation_learning+3

    Structure prediction backbone that swaps AlphaFold3-style triangle attention for triangle multiplication, cutting compute without losing accuracy.

    ProteinSmall molecule
    77Openness
  • PUMBA

    1
    Florida International UniversityOctober 19, 2025protein_protein_interactionrepresentation_learningstate_space_model+2

    Protein-protein docking scorer that ranks interface poses from image-encoded patches, swapping PIsToN's Vision Transformer for Vision Mamba.

    Protein
    20Openness
  • CortexMAE

    532107
    Sophont +1 otherOctober 15, 2025brain_state_decodingfmrifoundation_model+5

    fMRI foundation model trained on cortical flat-map videos with masked autoencoding, showing power-law scaling on brain activity reconstruction.

    Biosignals
    68Openness
  • PRISM

    6
    Carnegie Mellon University +2 othersOctober 13, 2025graph_neural_networkinverse_foldingprotein_design+3

    Retrieval-augmented inverse folding model that fuses structural motif retrieval with a hybrid attention decoder to design sequences for a backbone.

    Protein
    20Openness
  • ProteinAE

    212
    Chinese University of Hong Kong +2 othersOctober 12, 2025autoencoderde_novo_designdiffusion+5

    Protein structure autoencoder compressing backbone coordinates into a latent space, paired with a latent diffusion model for generative design.

    Protein
    74Openness
  • DiffTopo

    EPFLOctober 10, 2025de_novo_designdiffusiongenerative+3

    Diffusion model over coarse-grained protein topology that samples diverse folds, handing them to RFdiffusion to build de novo protein backbones.

    Protein
    20Openness
  • EvoIF

    Zhejiang University +1 otherOctober 8, 2025graph_neural_networkprotein_evolutionprotein_fitness_prediction+4

    Compact protein fitness predictor that fuses within-family evolutionary profiles with inverse-folding logits for zero-shot variant effect prediction.

    Protein
    26Openness
  • DynamicsPLM

    11
    Technion – Israel Institute of Technology +1 otherOctober 6, 2025conformational_dynamicsenzyme_function_predictionlanguage_model+4

    Protein language model conditioned on ensembles of computed conformations, giving state-aware embeddings for interaction, localization, and function.

    Protein
    65Openness
  • SLAE

    Stanford UniversityOctober 6, 2025all_atomautoencoderrepresentation_learning+2

    All-atom protein representation model that learns from each residue's strictly local atomic neighborhood, capturing side-chain geometry and chemistry.

    Protein
    20Openness
  • PLMNovo

    1
    Duke UniversityOctober 3, 2025de_novo_peptide_sequencingmass_spectrometryprotein_sequencing+4

    De novo peptide sequencing model that aligns tandem mass spectra with protein language model embeddings through constrained optimization.

    Protein
    19Openness
  • University of FloridaOctober 1, 2025binding_affinity_predictiondrug_discoverygraph_neural_network+4

    Geometric deep learning scoring function for protein-ligand binding affinity, pretrained on synthetic complexes and fine-tuned on PDBbind structures.

    ProteinSmall molecule
    71Openness
  • Shanghai Jiao Tong UniversityOctober 1, 2025brain_age_predictionbrain_mridensenet+8

    Brain MRI foundation model pairing DenseNet and Vision Transformer backbones with mixture of experts for disease diagnosis and brain age prediction.

    Imaging
    8Openness
  • BioVERSE

    2
    IBM ResearchOctober 1, 2025cell_biologycell_type_annotationcross_modal_question_answering+5

    Multimodal biomedical framework aligning frozen single-cell and protein model encoders to an LLM's embedding space for zero-shot reasoning.

    Language modelSingle-cellProtein
    23Openness
  • GCP-VQVAE

    432
    University of MissouriOctober 1, 2025graph_neural_networkprotein_structurerepresentation_learning+4

    Protein structure tokenizer that maps 3D backbones to discrete tokens with an SE(3)-equivariant encoder preserving orientation and chirality.

    Protein
    86Openness