All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 97–120 of 203 filtered models
NeuroVFM
554654University of Michigan +1 otherNovember 23, 2025ctfoundation_modeljoint_embedding_predictive_architecture+8Generalist neuroimaging vision foundation model pretrained on 5.24M clinical MRI and CT volumes for radiologic diagnosis and report generation.
Imaging57OpennessSIGMMA
—1—Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.
PathologySpatial omics20OpennessCryoSiam
201—European Molecular Biology LaboratoryNovember 12, 2025convolutional_neural_networkcryo_etdenoising+8Self-supervised Siamese network for cryo-electron tomography, enabling zero-shot denoising, segmentation, and macromolecule detection in tomograms.
Imaging64OpennessJWTH
—1—Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.
Pathology5OpennessAtacformer
28297Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.
Single-cellDNA & Gene32OpennessPaired heavy/light antibody language model fine-tuning ESM-2 and ESM-C with CDR-preferential masking for zero-shot binding affinity embeddings.
Protein8OpennessLSM-MS2
———Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.
MetabolomicsSmall molecule4OpennessSiamese protein language model whose embedding distances approximate TM-score and lDDT, enabling alignment-free protein structure comparison.
Protein5OpennessMetaboFM
—2—Georgia Institute of TechnologyOctober 23, 2025classificationfoundation_modelmass_spectrometry_imaging+6Vision Transformer foundation model for spatial metabolomics, pretrained on ~4,000 curated METASPACE mass spectrometry imaging datasets.
MetabolomicsSpatial omicsImaging10OpennessPairMixer
334—Genesis Therapeutics +1 otherOctober 21, 2025molecular_dockingprotein_designrepresentation_learning+3Structure prediction backbone that swaps AlphaFold3-style triangle attention for triangle multiplication, cutting compute without losing accuracy.
ProteinSmall molecule77OpennessPUMBA
—1—Florida International UniversityOctober 19, 2025protein_protein_interactionrepresentation_learningstate_space_model+2Protein-protein docking scorer that ranks interface poses from image-encoded patches, swapping PIsToN's Vision Transformer for Vision Mamba.
Protein20OpennessPRISM
—6—Carnegie Mellon University +2 othersOctober 13, 2025graph_neural_networkinverse_foldingprotein_design+3Retrieval-augmented inverse folding model that fuses structural motif retrieval with a hybrid attention decoder to design sequences for a backbone.
Protein20OpennessProteinAE
212—Protein structure autoencoder compressing backbone coordinates into a latent space, paired with a latent diffusion model for generative design.
Protein74OpennessEvoIF
———Zhejiang University +1 otherOctober 8, 2025graph_neural_networkprotein_evolutionprotein_fitness_prediction+4Compact protein fitness predictor that fuses within-family evolutionary profiles with inverse-folding logits for zero-shot variant effect prediction.
Protein26OpennessDynamicsPLM
11——Technion – Israel Institute of Technology +1 otherOctober 6, 2025conformational_dynamicsenzyme_function_predictionlanguage_model+4Protein language model conditioned on ensembles of computed conformations, giving state-aware embeddings for interaction, localization, and function.
Protein65OpennessSLAE
———All-atom protein representation model that learns from each residue's strictly local atomic neighborhood, capturing side-chain geometry and chemistry.
Protein20OpennessPLMNovo
—1—De novo peptide sequencing model that aligns tandem mass spectra with protein language model embeddings through constrained optimization.
Protein19OpennessGatorAffinity
351—Geometric deep learning scoring function for protein-ligand binding affinity, pretrained on synthetic complexes and fine-tuned on PDBbind structures.
ProteinSmall molecule71OpennessDenseFormer-MoE
—27—Brain MRI foundation model pairing DenseNet and Vision Transformer backbones with mixture of experts for disease diagnosis and brain age prediction.
Imaging8OpennessBioVERSE
—2—Multimodal biomedical framework aligning frozen single-cell and protein model encoders to an LLM's embedding space for zero-shot reasoning.
Language modelSingle-cellProtein23OpennessGCP-VQVAE
432—Protein structure tokenizer that maps 3D backbones to discrete tokens with an SE(3)-equivariant encoder preserving orientation and chirality.
Protein86Openness