University of Virginia

Modular deep-learning framework for 3D-structure-based RNA sequence design, pairing a direct GNN predictor (SCRU-Seq) and a diffusion model (SCRU-Diff) built on self-contained RNA units.

All-atom E(3)-equivariant diffusion model that refines RNA structures by resolving steric clashes and completing missing atoms.

Attention-based deep learning model that predicts gene expression from histone modification signals across 56 cell types with interpretable attention scores.