Academic

EPFL

A Swiss federal institute of technology in Lausanne, joining engineering, computer science, and life sciences with education and startup creation.

Location: Lausanne, Switzerland
Website
7 models(4 Imaging, 3 Protein, 1 Single-cell, 1 Spatial omics, 1 Language model)

Labs & Groups (1)

Models (7)

COSMIC

EPFL

Released January 24, 2026

Bidirectional generative framework linking nuclear morphology and gene expression, built on a morphology model trained on 21 million segmented nuclei.

ImagingSingle-cellSpatial omics

DiffTopo

EPFL

Released October 10, 2025

Diffusion model over coarse-grained protein topology that samples diverse folds, handing them to RFdiffusion to build de novo protein backbones.

Protein

ProteomeLM

EPFL

Released August 1, 2025

323836

Proteome-scale protein language model whose representations enable zero-shot protein-protein interaction and gene essentiality prediction.

Protein

EyeCLIP

The Hong Kong Polytechnic University / EPFL / Clemson University / Zhejiang University School of Medicine / Shanghai Jiao Tong University / Monash University

Released June 21, 2025

6487

CLIP-based vision-language foundation model for eye imaging, enabling zero-shot disease detection and cross-modal retrieval across 11 modalities.

ImagingLanguage model

RAG-ESM

EPFL

Released April 2, 2025

1627

Retrieval-augmented protein language model that conditions ESM-2 on homologous sequences via cross-attention for conditional sequence generation.

Protein

EyeFound

The Hong Kong Polytechnic University / Sun Yat-sen University / National University of Singapore / EPFL

Released May 18, 2024

43

Ophthalmic imaging foundation model pretrained on 2.78M images across 11 modalities for diagnosis, prognosis, and visual question answering.

Imaging

CellSeg3D

Mathis Lab

Released May 17, 2024

1122

Self-supervised 3D cell segmentation for fluorescence microscopy, pairing WNet3D with Swin-UNetR to segment volumes without annotated training data.

Imaging