All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 159 filtered models
DaX
2——Pathology vision foundation model adapting DINOv3-style self-supervised learning to whole-slide histopathology across continuous magnifications and scales.
Pathology11OpennessFlashABB
8——Oxford Protein Informatics Group (OPIG)June 4, 2026antibodydevelopability_predictionfoundation_model+4Pretrained antibody structure predictor that outputs full paired heavy/light 3D structures faster than protein language models generate embeddings.
Protein54OpennessReCLIP
———University of Chicago +2 othersJune 4, 2026multi_taskpeptide_mhc_binding_predictionprotein_protein_interaction_prediction+5Transformer framework that models protein-protein interactions at residue resolution, generalizing zero-shot to unseen MHC alleles and sequence-neutral PTMs from one fixed checkpoint.
Protein22OpennessLDARNet
—1—A 120M-parameter genomic foundation model that learns adaptive DNA token boundaries via H-Net-style dynamic chunking instead of fixed k-mer or byte-pair tokenization.
DNA & Gene26OpennessmiDGD
———A deep generative decoder that infers microRNA expression directly from bulk or single-cell mRNA gene expression via a shared mRNA/miRNA latent space.
RNASingle-cell8OpennessCryoProt
———Protein pretraining framework that learns representations directly from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.
ImagingProtein11OpennessTESSERA
5——Self-supervised foundation model that learns reusable representations of cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types.
DNA & Gene28OpennessTxFM
2——A self-supervised masked autoencoder for RNA-seq count data, pretrained on 1.4M public samples to learn transferable transcriptomic representations without per-dataset re-training.
Single-cell12OpennessGlucoFM
———Google Research +1 otherMay 29, 2026continuous_glucose_monitoringfoundation_modelglucose_forecasting+4A dual-stream self-supervised foundation model for continuous glucose monitoring data, separating slow physiological state from transient glucose events.
Biosignals11OpennessGenBloom
3——Genetically aligned foundation model for blood smear cytology that links single white-blood-cell morphology to chromosomal aberrations and mutations for AML/APL diagnosis.
Pathology65OpennessFlowTransOP
———A constrained deep flow-matching framework for distributional translation of omics signatures across biological domains, such as mouse-to-human transcriptomics, without paired samples.
Single-cell87OpennessLucaPhylo
5——A hyperbolic protein language model for alignment-free phylogenetic inference, producing distance matrices for tree placement without multiple sequence alignment.
Protein86OpennessTMEformer
———A spatial-transcriptomics foundation model for the tumor microenvironment that produces TME-aware embeddings and enables in silico perturbation from a fixed pretrained checkpoint.
Spatial omics10OpennessSE(3)-invariant masked autoencoder pretrained on ~370K AlphaFold-DB structures for protein fold representation learning, enabling frozen-feature and zero-shot fold classification.
Protein78OpennessPLM-SAE
———A mechanistic-interpretability framework that trains sparse autoencoders on protein language model embeddings to extract interpretable features for zero-shot variant effect prediction.
Protein22OpennessENSEMBITS
7——A residual VQ-VAE tokenizer that learns a discrete alphabet of protein conformational ensembles from molecular dynamics data, usable as a frozen representation layer for downstream tasks.
Protein66OpennessSusagi
7—3A permutation-invariant denoising transformer trained on ~2 million bacterial community samples to learn member-level stability scores and predict microbiome composition dynamics zero-shot.
DNA & Gene48OpennessBRIDGE
———The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8A multi-organ foundation model aligning histology image features with spatial-transcriptomics gene expression across 13 organs for zero-shot virtual ST and survival prediction.
PathologySpatial omics31OpennessProtSent
6——Contrastively fine-tuned ESM-2 (35M and 150M) protein language models that produce general-purpose sequence embeddings where biological similarity maps to embedding proximity.
Protein87OpennessWaypoint
———A family of GPT-2-style causal language models pretrained on 539,000+ microbiome samples, enabling zero- and few-shot transfer across microbiome prediction tasks.
DNA & Gene23OpennessBrainDINO
3——Emory University +2 othersApril 30, 2026brain_age_estimationdisease_classificationfoundation_model+6A self-supervised DINOv3-based foundation model for brain MRI, pretrained on ~6.6M unlabeled axial slices and transferable to diverse neuroimaging tasks.
Imaging49OpennessPeptideCLM-2
8——SMILES-based chemical language models pretrained on 100M+ molecules to natively represent therapeutic peptide chemistry, including non-canonical residues.
Small moleculeProtein79OpennessDIA-CLIP
———AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6A CLIP-style dual-encoder model that learns a shared peptide-spectrum representation for zero-shot peptide-spectrum-match inference in DIA proteomics.
Protein11Openness