All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 18 of 8 filtered models

  • BioMatrix

    41162
    Shanghai AI Laboratory +1 otherJune 20, 2026foundation_modellanguage_modelmolecule_generation+6

    Decoder-only foundation model that unifies sequences, 3D structures, and natural language for small molecules and proteins in one shared token space.

    ProteinSmall moleculeLanguage model
    67Openness
  • Pengcheng Laboratory +2 othersMarch 13, 2026chain_of_thoughtcheminformaticsdrug_discovery+6

    Molecular reasoning model built on DeepSeek-7B, using chain-of-thought and reinforcement learning for property prediction, generation, and reactions.

    Small moleculeLanguage model
    21Openness
  • MMPT-RAG

    1
    Emory UniversityFebruary 18, 2026drug_discoveryfoundation_modelgenerative+3

    Retrieval-augmented model for matched molecular pair transformations, proposing localized analog edits guided by retrieved reference compounds.

    Small molecule
    16Openness
  • Keshav Memorial Engineering CollegeFebruary 6, 2026diffusiondrug_discoverygenerative+3

    E(3)-equivariant diffusion model for macrocycle design that turns acyclic molecules into macrocycles, with a transformer choosing where to cyclize.

    Small molecule
    8Openness
  • GEMGen

    2
    Westlake University +1 otherJanuary 3, 2026de_novo_designdrug_discoverygenerative+5

    Generative language model for phenotype-driven drug discovery, proposing small-molecule structures from up- and down-regulated gene signatures.

    Small moleculeSingle-cell
    9Openness
  • FlexiFlow

    AstraZeneca +4 othersNovember 21, 2025conformer_generationde_novo_designdrug_discovery+7

    Flow-matching model that jointly samples 3D de novo molecules and several low-energy conformers, extending to pocket-conditioned ligand design.

    Small moleculeProtein
    19Openness
  • Apo2Mol

    37
    University of FloridaNovember 18, 2025binding_pocketde_novo_designdiffusion+5

    Diffusion model for structure-based drug design that jointly generates 3D ligands and holo pocket conformations from an apo protein structure.

    Small moleculeProtein
    65Openness
  • UniLingo3DMol

    183
    StoneWiseNovember 14, 2025de_novo_designdrug_discoverygenerative+5

    Pretrained language model for 3D molecule generation in protein pockets, unifying de novo and fragment-based drug design in one multi-task framework.

    Small molecule
    8Openness