AstraZeneca

Histopathology-to-molecular alignment model that queries H&E slides with gene-set signatures to predict pathway activity without sequencing.

Transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, with no 3D structure step.

Flow-matching model that jointly samples 3D de novo molecules and several low-energy conformers, extending to pocket-conditioned ligand design.

Antibody language model that generates paired heavy and light variable domains, with a developability-conditioned variant for manufacturable designs.