All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 49–72 of 943 models
Tox21mer
———National Institute of Environmental Health SciencesJune 15, 2026embeddingsfoundation_modelrepresentation_learning+2Toxicity screening foundation model that encodes Tox21 concentration-response curves and assay metadata into reusable 768-dimensional embeddings.
Small moleculeBiosignals23OpennessRepGene
—11—Gene representation framework fusing DNA, transcript, protein, text, and single-cell embeddings into one latent space that survives missing views.
DNA & GeneProteinSingle-cell22OpennessOmnii
———Genomic language model from Radical Numerics with a 2 Mbp context window, built for zero-shot variant effect prediction and sequence design.
DNA & Gene5OpennessTCRDiff
7——Conditional denoising diffusion model that designs antigen-specific TCR CDR3β sequences conditioned on peptide-MHC targets and germline V-genes.
Protein75OpennessBetaInfer
———Technion – Israel Institute of Technology +2 othersJune 14, 2026generativegenomicsmolecular_evolution+4Generative transformer for phylogenetic inference that transduces sets of unaligned molecular sequences directly into Newick-format trees.
DNA & GeneProtein8OpennessMoE-Bind
2——Protein binder generator producing receptor-conditioned binders from sequence alone, using a sparse Mixture-of-Experts transformer with no 3D input.
Protein54OpennessRDiffusion
———Diffusion-based generative RNA model for de novo sequence design, conditioned on function, RNA family, structure, or binding proteins.
RNA5OpennessRNARL
—146—Reinforcement-learning generative framework for multi-objective RNA codon optimization that generalizes across six species and five RNA types.
RNA4OpennessDNAGPT2
———Family of ten compact GPT-2 decoder-only DNA language models spanning BPE vocabularies from 16 to 8192 tokens, built for lossless genome compression.
DNA & Gene52OpennessGermRL
1—4Reinforcement learning framework that fine-tunes the ProGen2-OAS antibody language model with GRPO to cut germline bias in generated sequences.
Protein65OpennessHBDesigner
154—Message-passing neural network that designs buried hydrogen-bond networks onto protein backbones, combining learned placement with PyRosetta scoring.
Protein60OpennessHoloCell
—203—860M-parameter generative single-cell foundation model that jointly represents and generates epigenomic, transcriptomic, and proteomic modalities.
Single-cellDNA & Gene21OpennessTifBERT
2——Bulk RNA-seq foundation model learning normalization-robust transcriptome representations via TF-IDF gene ordering and masked gene modeling.
RNA17OpennessRhaister
——23Perturbation-response predictor built on screen-level summary statistics, inferring unmeasured drug and genetic responses in new cellular contexts.
Single-cellSmall molecule91OpennessBacteReason
———University of TokyoJune 7, 2026antimicrobial_resistanceantimicrobial_resistance_predictionbacteria+5Reasoning LLM that predicts antimicrobial susceptibility of clinical bacterial isolates and supplies mechanistic explanations for each prediction.
DNA & GeneLanguage model20OpennessCREP
———Fine-tuned Enformer derivative that annotates cis-regulatory elements from DNA sequence, emitting enhancer, promoter, and insulator class labels.
DNA & Gene8OpennessMethylSeqNet
—1—University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6Gene regulation model that conditions a pretrained DNA sequence embedding on CpG methylation to capture cell-type and allele-specific regulation.
DNA & Gene18OpennessSpineAgent
611—Multi-sequence spine MRI foundation model with DINOv3 encoders, supporting condition classification, pathology localization, and report generation.
Imaging55OpennessVelocityFM
———University of Colombo School of Computing +1 otherJune 7, 2026conformational_samplingflow_matchinggenerative+4Generative protein-dynamics model that predicts short molecular dynamics trajectories with rectified flow matching over residue frames and torsions.
Protein21OpennessCryoDiff
———Uncertainty-aware diffusion model that enhances cryo-EM density maps while estimating voxel-wise confidence via Monte Carlo sampling.
Imaging20OpennessCellpin
———Variational autoencoder trained on scRNA-seq and applied frozen to impute unmeasured genes and denoise spatial transcriptomics profiles.
Spatial omicsSingle-cell22OpennessDaX
2——Pathology vision foundation model adapting DINOv3 self-supervised learning to whole-slide histopathology across many magnifications and scales.
Pathology11Opennesstf-SFM
—2—Transcription factor-DNA binding specificity prediction from sequence, with a physics-derived dual-encoder trained by symmetric contrastive learning.
DNA & Gene18Openness