Northwestern Polytechnical University

Olfactory receptor-odorant interaction prediction from sequence and SMILES, pairing protein and chemical language models through cross-attention.

Virtual spatial transcriptomics model that infers spot-level gene expression from H&E slides by fusing tile, slide, and spatial-position features.

Diffusion model for de novo AAV capsid design that steers sampling with a viability classifier toward assemblable, packaging-competent variants.

Enzyme backbone design model that adds substrate and catalytic-site control to a pretrained SE(3) flow-matching generator via a lightweight adapter.

TCR-antigen binding prediction that adapts ESM-2 with LoRA on antigen-specific receptors and fuses the embeddings with a bipartite interaction graph.

T-cell receptor specificity prediction that separates general antigens from autoimmune-related ones using ESM-2 embeddings and a topology-aware graph.

3D CT segmentation of abdominal organs and tumors, where a deformable-attention Transformer decodes organ embeddings into the segmentation kernels.

Multi-organ and tumor segmentation in 3D abdominal CT from a single network whose segmentation kernels are generated per task by a controller.