All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 2548 of 943 models

  • RNArefine

    1
    National University of Singapore +2 othersJune 29, 2026cryo_emgraph_neural_networkrepresentation_learning+2

    Atomic-level refinement of RNA 3D structures, using geometric attention networks to guide physics-based Monte Carlo sampling and L-BFGS optimization.

    RNA
    32Openness
  • ProLoc

    Nanjing UniversityJune 27, 2026functional_region_localizationlanguage_modelmultimodal+3

    Text-guided localization model that grounds natural-language functional descriptions to specific residue regions of a protein sequence.

    ProteinLanguage model
    10Openness
  • eRNAformer

    2
    Nanchang UniversityJune 27, 2026cnnenhancer_annotationgenomics+5

    Enhancer RNA mapping model that locates eRNA loci genome-wide from DNA sequence and aggregated RNA-seq signal using a CNN-transformer architecture.

    DNA & GeneRNA
    95Openness
  • PertOmni

    Yale University +2 othersJune 26, 2026cell_biologycontrastive_learningdrug_gene_interaction+6

    Contrastive multimodal model for perturbation screens, aligning transcriptomic signatures with text and cell-painting image embeddings.

    Single-cellSmall molecule
    18Openness
  • ZAO

    SyntheticGestaltJune 25, 2026admet_predictionfoundation_modelrepresentation_learning+1

    Molecular foundation model that turns SMILES into 2048-dimensional embeddings from multiple 3D conformations for ADMET and virtual screening.

    Small molecule
    16Openness
  • PlantGeneAnn

    12122
    Huazhong Agricultural UniversityJune 25, 2026dnafoundation_modelgene_structure_annotation+7

    Plant genome foundation model for ab initio gene structure annotation, predicting genes, coding sequences, and exons at single-nucleotide resolution.

    DNA & Gene
    66Openness
  • ComplexDesign

    Institute of Computing Technology, Chinese Academy of SciencesJune 24, 2026binder_designde_novo_designgenerative+4

    Hallucination-based multichain protein design framework that co-folds chains and forms the inter-chain interfaces of dimers, trimers, and tetramers.

    Protein
    21Openness
  • Max Delbrück Center for Molecular MedicineJune 24, 2026gene_expressiongenerativerepresentation_learning+4

    Supervised variational autoencoder that learns a tissue-aware latent space for bulk RNA-seq, trained on harmonized TCGA, GTEx, and ARCHS4 data.

    RNA
    84Openness
  • Molexar

    526
    Peking UniversityJune 24, 2026de_novo_designdrug_designdrug_discovery+5

    Multimodal molecular generation model for drug design, conditioned on properties, pharmacophores, protein sequences, or protein binding pockets.

    Small moleculeProtein
    82Openness
  • Navigo

    1211
    Chinese University of Hong Kong +1 otherJune 24, 2026cell_fate_engineeringflow_matchinggene_regulatory_network_inference+6

    Generative framework that learns a developmental vector field from scRNA-seq snapshots, coupling flow matching with molecular RNA kinetics.

    Single-cellRNA
    44Openness
  • V3Cell

    Xinjiang Technical Institute of Physics and Chemistry +2 othersJune 24, 2026cell_biologydrug_discoverygenerative+4

    Vision-guided model that builds virtual 3D organoid surrogates from brightfield microscopy to predict chemical perturbation responses without omics.

    ImagingPathology
    4Openness
  • CellOS

    Vitaura +2 othersJune 23, 2026batch_integrationcell_type_annotationfoundation_model+6

    Multi-view single-cell foundation model at 12B parameters, aligning expression and perception views with an LLM-JEPA joint-embedding objective.

    Single-cell
    8Openness
  • Helmholtz MunichJune 22, 2026cell_biologycontrastive_learningfluorescence_microscopy+6

    Self-supervised 3D masked autoencoder for volumetric fluorescence microscopy, aligned to ESM2 embeddings to predict protein localization.

    ImagingSingle-cell
    71Openness
  • Washington University in St. LouisJune 22, 2026cell_biologycell_type_annotationgene_expression+5

    Single-cell language model that prepends biomedical knowledge-graph tokens to cell sentences, grounding cell type annotation in pathway structure.

    Single-cellLanguage model
    23Openness
  • EventHorizon

    ARUP Laboratories +1 otherJune 22, 2026cell_type_annotationdiagnostic_classificationflow_cytometry+6

    Self-supervised foundation model for clinical flow cytometry, producing panel-agnostic specimen-level representations from multi-panel data.

    BiosignalsSingle-cell
    4Openness
  • Sesame

    Tessel BiosciencesJune 22, 2026de_novo_designdiffusiondrug_discovery+3

    Diffusion model that generates 3D small molecules conditioned on protein pockets and partial fragments encoded as continuous spatial density maps.

    Small moleculeProtein
    15Openness
  • JEDEL

    4
    University of Southampton +1 otherJune 21, 2026de_novo_designdna_encoded_librariesdrug_discovery+6

    Zero-shot generative framework that turns 3D pharmacophores into synthesis-ready DNA-encoded libraries of purchasable building blocks.

    Small molecule
    23Openness
  • BioMatrix

    41162
    Shanghai AI Laboratory +1 otherJune 20, 2026foundation_modellanguage_modelmolecule_generation+6

    Decoder-only foundation model that unifies sequences, 3D structures, and natural language for small molecules and proteins in one shared token space.

    ProteinSmall moleculeLanguage model
    67Openness
  • RNAJog

    2
    Shanghai Jiao Tong UniversityJune 20, 2026autoregressivecodoncodon_optimization+7

    Autoregressive generative model that uses reinforcement learning to optimize mRNA codon sequences for MFE, CAI, and GC content.

    RNA
    9Openness
  • UltraNMR

    1
    Hong Kong University of Science and Technology +4 othersJune 18, 2026foundation_modelself_supervisedtransfer_learning+1

    NMR foundation model trained on 158 million simulated 1H and 13C spectra, transferring simulation-learned representations to real experimental data.

    Small moleculeMetabolomics
    43Openness
  • GENATATOR

    52
    AIRI InstituteJune 17, 2026gene_annotationgene_structure_predictiontransfer_learning+2

    Ab initio gene annotation model that predicts gene boundaries and exon-intron structure from raw DNA, generalizing zero-shot to unseen species.

    DNA & GeneRNA
    22Openness
  • BoltzMol-1

    4.1K
    BoltzJune 16, 2026diffusiondrug_discoveryfoundation_model+4

    Small-molecule hit-discovery pipeline using Boltz-2 co-folding and affinity prediction to rank in-stock compounds or make-on-demand chemical space.

    Small moleculeProtein
    7Openness
  • BoltzProt-1

    4.1K
    BoltzJune 16, 2026antibodybinder_designfoundation_model+5

    De novo protein binder and nanobody design pipeline that ranks candidates by a protein-protein interaction model rather than structural confidence.

    Protein
    11Openness
  • vBx-1.0

    Verge LabsJune 16, 2026contrastive_learningfoundation_modelgene_expression+5

    Multimodal foundation model for precision neurology that reconstructs a patient's molecular brain state from blood to predict disease progression.

    Single-cellDNA & Gene
    5Openness