All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 385408 of 943 models

  • Carnegie Mellon UniversityNovember 27, 2025gene_expressiongenerativelanguage_model+4

    Spatial transcriptomics language model that reads tissue as spatial sentences to simulate cell profiles and run in silico perturbations.

    Spatial omicsSingle-cell
    53Openness
  • PULSAR

    363211
    Stanford UniversityNovember 26, 2025biomarker_predictiondisease_classificationfoundation_model+6

    Hierarchical single-cell foundation model that turns scRNA-seq profiles into zero-shot donor-level embeddings for disease and biomarker prediction.

    Single-cellProtein
    58Openness
  • Technion – Israel Institute of Technology +1 otherNovember 26, 2025function_predictiongraph_neural_networkmultimodal+4

    Multimodal protein representation model that iteratively fuses a sequence language model with a 3D structure encoder through a shared learnable token.

    Protein
    68Openness
  • RNA-X

    4
    Bilkent UniversityNovember 26, 2025de_novo_designfoundation_modelmasked_language_model+5

    RNA interaction foundation model for conditional, zero-shot design of RNA sequences that bind protein, DNA, or RNA targets without retraining.

    RNAProtein
    6Openness
  • Brown UniversityNovember 25, 2025dnafoundation_modelgenomics+5

    Bidirectional state-space (Mamba-2) genomic model for ultra-long extrachromosomal circular DNA, scaling linearly with sequence length.

    DNA & Gene
    54Openness
  • BoltzGen

    1K78
    MITNovember 24, 2025antibodybinder_designde_novo_design+5

    All-atom generative model for de novo protein and peptide binder design against diverse biomolecular targets, wet-lab validated across 26 targets.

    ProteinSmall molecule
    78Openness
  • University of Maryland, College ParkNovember 24, 2025codon_optimizationde_novo_designfoundation_model+6

    Conditional codon language model with 150M parameters that generates species-optimized coding sequences from a protein and its taxonomic lineage.

    DNA & GeneRNA
    90Openness
  • Eindhoven University of TechnologyNovember 24, 2025cell_biologycell_morphology_simulationconditional_generation+5

    Flow-matching generative model that synthesizes fluorescence images of human fibroblasts conditioned on surface micro-topographies.

    Imaging
    5Openness
  • MIMYR

    138
    Carnegie Mellon UniversityNovember 24, 2025cell_biologycell_type_annotationdata_imputation+6

    Generative framework that reconstructs missing spatial transcriptomics regions by jointly predicting cell locations, cell types, and gene expression.

    Spatial omicsSingle-cell
    16Openness
  • Melody

    18
    Shandong University +2 othersNovember 23, 2025cnndna_methylationepigenomics+5

    Deep learning framework that predicts DNA methylation from genomic sequence across 39 human tissues, with an scRNA-seq variant for unseen cell types.

    DNA & Gene
    8Openness
  • NeuroVFM

    52466
    University of Michigan +1 otherNovember 23, 2025ctfoundation_modeljoint_embedding_predictive_architecture+8

    Generalist neuroimaging vision foundation model pretrained on 5.24M clinical MRI and CT volumes for radiologic diagnosis and report generation.

    Imaging
    57Openness
  • FlexiFlow

    AstraZeneca +4 othersNovember 21, 2025conformer_generationde_novo_designdrug_discovery+7

    Flow-matching model that jointly samples 3D de novo molecules and several low-energy conformers, extending to pocket-conditioned ligand design.

    Small moleculeProtein
    19Openness
  • Puget

    University of WashingtonNovember 20, 2025chromatindnafoundation_model+6

    Gene expression prediction model combining DNA sequence with Hi-C contact maps to capture 3D chromatin looping behind cell-type-specific expression.

    DNA & Gene
    8Openness
  • MethylAI

    7
    Guangzhou National LaboratoryNovember 20, 2025cnndnaepigenetics+6

    Cross-species-pretrained CNN that predicts single-CpG DNA methylation from genomic sequence and interprets the cis-regulatory motifs that govern it.

    DNA & Gene
    64Openness
  • Evo2HiC

    92
    University of WashingtonNovember 19, 2025chromatinchromatin_contact_predictionepigenomic_profiling+9

    Multimodal foundation model that distills Evo 2 into a compact encoder guided by Hi-C data, predicting cell-type-specific 3D genome architecture.

    DNA & GeneSpatial omics
    57Openness
  • SIGMMA

    1
    Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7

    Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.

    PathologySpatial omics
    20Openness
  • SHEST

    129
    Samsung Advanced Institute for Health Sciences and Technology +2 othersNovember 19, 2025cell_type_annotationgene_expressionhistology+5

    Histopathology model that predicts single-cell type composition and reconstructs spatial gene expression from H&E slides, with no molecular assay.

    PathologySpatial omics
    16Openness
  • Uni-Hema

    1
    Information Technology University of the Punjab +1 otherNovember 18, 2025classificationcnnfoundation_model+8

    Digital hematopathology foundation model unifying blood-cell detection, classification, segmentation, and visual question answering.

    Pathology
    8Openness
  • Apo2Mol

    37
    University of FloridaNovember 18, 2025binding_pocketde_novo_designdiffusion+5

    Diffusion model for structure-based drug design that jointly generates 3D ligands and holo pocket conformations from an apo protein structure.

    Small moleculeProtein
    65Openness
  • MergeDNA

    5
    Westlake University +1 otherNovember 17, 2025foundation_modelgenomicsmulti_omics+6

    Hierarchical DNA foundation model that co-trains a dynamic token-merging tokenizer with latent Transformers to match genomic information density.

    DNA & Gene
    5Openness
  • UniLingo3DMol

    183
    StoneWiseNovember 14, 2025de_novo_designdrug_discoverygenerative+5

    Pretrained language model for 3D molecule generation in protein pockets, unifying de novo and fragment-based drug design in one multi-task framework.

    Small molecule
    8Openness
  • ConformAb

    1
    GenentechNovember 13, 2025antibodyantibody_designdiffusion+5

    Guided discrete diffusion model for antibody lead optimization, conditioning sequence design on the seed binder's CDR canonical backbone conformation.

    Protein
    18Openness
  • E1

    1131019.1K
    ProfluentNovember 13, 2025contact_predictionfoundation_modelproteomics+6

    Retrieval-augmented protein encoders that fuse homologous sequences into a single-pass transformer for variant effect and contact prediction.

    Protein
    47Openness
  • CryoSiam

    201
    European Molecular Biology LaboratoryNovember 12, 2025convolutional_neural_networkcryo_etdenoising+8

    Self-supervised Siamese network for cryo-electron tomography, enabling zero-shot denoising, segmentation, and macromolecule detection in tomograms.

    Imaging
    64Openness