Cornell University

Tandem mass spectrum prediction that builds explicit fragmentation pathways, mapping unknown spectra onto 800 million predicted PubChem spectra.

Long-context plant DNA language model, 676M parameters on a Mamba2 backbone, pretrained on 65 angiosperm genomes for cross-species variant annotation.

Multi-species genomics foundation model spanning representation learning, functional-track prediction, and sequence generation at 1 Mb context.

Missense variant pathogenicity predictor that also ranks candidate diseases, aligning ESM-2 protein embeddings with PubMedBERT disease text.

Autoregressive graph transformer generating molecules as node and edge token sequences, fine-tunable for goal-directed design and property prediction.

Long-context protein language model on a bidirectional Mamba backbone, outperforming ESM-2 by up to 30% at matched training token budgets.

Keypoint-based foundation model for brain MRI registration, pretrained on over 100,000 3D volumes for rigid, affine, and deformable alignment.

Bidirectional, reverse-complement equivariant DNA language models built on Mamba state space models for long-range variant effect prediction.

Medical image segmentation model that solves unseen segmentation tasks in context from a few labeled examples, with no retraining or fine-tuning.