All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 913936 of 943 models

  • BERT6mA

    516
    Kyushu Institute of TechnologyMarch 10, 2022dna_methylationepigenomic_predictionepigenomics+4

    BERT-based predictor of DNA N6-methyladenine (6mA) modification sites, using word2vec encoding and cross-species transfer learning.

    DNA & Gene
    45Openness
  • RNABERT

    561341.7K
    Keio UniversityFebruary 22, 2022foundation_modellanguage_modelstructure_prediction

    RNA language model that learns base-level embeddings capturing sequence context and secondary structure, enabling fast structural alignment.

    RNA
    34Openness
  • OntoProtein

    152140214
    Zhejiang UniversityJanuary 28, 2022foundation_modelgene_ontologyknowledge_graph+1

    Protein language model that fuses Gene Ontology knowledge graphs with masked language modeling, improving protein function and interaction prediction.

    Protein
    63Openness
  • ProteinBERT

    579
    Hebrew University of JerusalemJanuary 13, 2022foundation_modelgene_ontologylanguage_model+1

    Protein language model pretrained on UniRef90 with masked language modeling and Gene Ontology annotation prediction, at 16 million parameters.

    Protein
    86Openness
  • Ghent UniversityJanuary 12, 2022dna_methylationdna_methylation_imputationepigenomic_prediction+4

    Transformer that imputes missing CpG methylation states from sparse single-cell bisulfite sequencing, modeling genomic and cell-level structure.

    DNA & Gene
    79Openness
  • AbLang

    167216
    Oxford Protein Informatics Group (OPIG)January 1, 2022antibodyfoundation_modelimmunology+2

    Antibody-specific language model trained on the OAS database for restoring missing residues and generating high-quality sequence representations.

    Protein
    62Openness
  • PubMedCLIP

    183287.1K
    Hasso Plattner InstituteDecember 27, 2021cnncontrastive_learninghistology+8

    Medical-domain CLIP fine-tuned on radiology image-caption pairs from ROCO, serving as a drop-in visual encoder for medical visual question answering.

    PathologyLanguage model
    75Openness
  • BioSeq-BLM

    14230
    Beijing Institute of TechnologyDecember 16, 2021dnafoundation_modelsequence_analysis

    Unified platform implementing 155 biological language models for DNA, RNA, and protein sequence analysis at residue and sequence level.

    Language modelProtein
    48Openness
  • GeneBERT

    27
    Carnegie Mellon UniversityOctober 11, 2021bertchromatinfoundation_model+6

    Multi-modal self-supervised transformer for regulatory genomics, pre-trained on DNA sequence together with transcription factor binding matrices.

    DNA & Gene
    18Openness
  • AlphaFold-Multimer

    14.7K3.2K
    Google DeepMindOctober 4, 2021foundation_modelproteomicsstructure_prediction+1

    Protein complex structure prediction model extending AlphaFold 2 with paired MSA processing and ipTM scoring for multi-chain, multimeric assemblies.

    Protein
    59Openness
  • Enformer

    15.1K1.2K
    Google DeepMindOctober 4, 2021dnafoundation_modelgene_expression+2

    Transformer that predicts gene expression and epigenomic signals from 200kb of DNA sequence, capturing distal enhancers up to 100kb from a promoter.

    DNA & Gene
    84Openness
  • ProtTrans

    1.3K
    RostlabAugust 1, 2021embeddingsfoundation_modelself_supervised+1

    Suite of six protein language models, including ProtBERT and ProtT5, trained on up to 393 billion amino acids without multiple sequence alignments.

    Protein
    71Openness
  • AlphaFold 2

    14.7K37.5K
    Google DeepMindJuly 15, 2021foundation_modelstructure_prediction

    Protein structure prediction model that folds amino acid sequences into 3D structures with atomic accuracy, scoring a median GDT of 92.4 at CASP14.

    Protein
    61Openness
  • ESM-1v

    4.2K898
    Meta AIJuly 9, 2021foundation_modellanguage_modelvariant_effect_prediction

    Protein language model for zero-shot variant effect prediction, scoring mutations by log-odds from evolutionary sequences with no MSA or assay data.

    Protein
    72Openness
  • CPA

    149316
    Theis LabApril 15, 2021autoencoderdrug_response_modelinggenerative+5

    Single-cell perturbation prediction model that forecasts transcriptional responses to drug combinations and doses never experimentally measured.

    Single-cell
    78Openness
  • ESM-1b

    4.2K3.9K
    Meta AIApril 5, 2021embeddingsfoundation_modelvariant_effect_prediction

    Transformer protein language model trained on 250 million protein sequences that learns structural and functional representations without supervision.

    Protein
    71Openness
  • DNABERT

    768813.8K
    Northwestern UniversityFebruary 4, 2021dnafoundation_modelgenomics+2

    Bidirectional transformer for DNA using k-mer tokenization, fine-tunable for promoter, splice site, and transcription factor binding prediction.

    DNA & Gene
    61Openness
  • Cellpose

    2.3K3.6K
    HHMI Janelia Research CampusDecember 7, 2020brightfieldcell_biologyfluorescence_microscopy+2

    Generalist deep learning algorithm for cell and nucleus instance segmentation using simulated diffusion flows, without per-dataset retraining.

    Imaging
    92Openness
  • scVAE

    89
    Technical University of Denmark +1 otherAugust 15, 2020autoencodergene_expressionvariational_autoencoder

    Variational autoencoder for single-cell RNA-seq that models raw counts directly, learning latent cell representations without normalization.

    Single-cell
    53Openness
  • Basenji2

    473223
    Calico Life SciencesAugust 6, 2020chromatincnngene_expression+5

    Cross-species convolutional network trained jointly on human and mouse genomes to predict regulatory sequence activity and noncoding variant effects.

    DNA & Gene
    79Openness
  • Big Bird

    6333K338.9K
    Google ResearchJuly 28, 2020dnafoundation_modelgenomics+4

    Sparse attention transformer that extends BERT to 8x longer sequences via random, local, and global attention, with genomic sequence applications.

    DNA & Gene
    49Openness
  • Arizona State University +1 otherAugust 19, 2019classificationcnnct+7

    Self-supervised 3D pretrained models for CT and MRI that learn anatomical representations from unlabeled volumes and transfer to segmentation tasks.

    Imaging
    20Openness
  • scGen

    353653
    Theis LabJuly 29, 2019batch_correctiongenerativeout_of_distribution_generalization+4

    Variational autoencoder that predicts single-cell perturbation responses across cell types and species using latent space vector arithmetic.

    Single-cell
    43Openness
  • Med3D

    2.2K28
    TencentAILabHealthcareApril 1, 20193d_resnetcnnct+8

    Pretrained 3D-ResNet backbones for volumetric medical image analysis, co-trained across eight CT and MRI segmentation datasets for transfer learning.

    Imaging
    75Openness