All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 457480 of 943 models

  • GeneJEPA

    345
    Biostate AIOctober 14, 2025cell_type_annotationfoundation_modelperturbation_prediction+2

    Self-supervised single-cell foundation model that predicts masked gene embeddings in latent space using a joint-embedding predictive architecture.

    Single-cell
    44Openness
  • PRISM

    5
    Carnegie Mellon University +2 othersOctober 13, 2025graph_neural_networkinverse_foldingprotein_design+3

    Retrieval-augmented inverse folding model that fuses structural motif retrieval with a hybrid attention decoder to design sequences for a backbone.

    Protein
    20Openness
  • RADiAnce

    Tsinghua University +1 otherOctober 12, 2025antibodybinder_designcontrastive_learning+6

    Retrieval-augmented latent diffusion model for protein binder design, retrieving interfaces in a shared latent space across peptides and antibodies.

    Protein
    26Openness
  • ProteinAE

    214
    Chinese University of Hong Kong +2 othersOctober 12, 2025autoencoderde_novo_designdiffusion+5

    Protein structure autoencoder compressing backbone coordinates into a latent space, paired with a latent diffusion model for generative design.

    Protein
    74Openness
  • FcGPT

    ETH ZurichOctober 11, 2025antibodyde_novo_designgenerative+4

    Autoregressive protein language model for antibody Fc domains, reinforcement-tuned to design variants with programmable Fc-receptor binding profiles.

    Protein
    20Openness
  • MIMO

    12202
    Peking University +1 otherOctober 11, 2025histologyinstruction_tuningmultimodal+6

    Medical vision-language model that takes visual prompts on an image and returns answers grounded in pixel-level segmentation masks.

    ImagingLanguage model
    11Openness
  • FlexRibbon

    2
    Beijing Zhongguancun AcademyOctober 10, 2025diffusionfoundation_modelmultimodal+5

    Protein foundation model with 3B parameters, pretrained jointly on sequence and 3D structure via masked language modeling and diffusion denoising.

    Protein
    20Openness
  • DiffTopo

    EPFLOctober 10, 2025de_novo_designdiffusiongenerative+3

    Diffusion model over coarse-grained protein topology that samples diverse folds, handing them to RFdiffusion to build de novo protein backbones.

    Protein
    20Openness
  • MagicDock

    Beijing Institute of TechnologyOctober 10, 2025autoencoderde_novo_designdrug_discovery+5

    De novo ligand design framework that generates protein binders and small molecules by inverting gradients through a differentiable docking model.

    ProteinSmall molecule
    33Openness
  • University of Notre Dame +2 othersOctober 9, 2025diffusiondrug_discoveryfew_shot+5

    Graph diffusion transformer for in-context molecular design, adapting to new tasks from a few molecule-property demonstrations without fine-tuning.

    Small molecule
    74Openness
  • EvoIF

    Zhejiang University +1 otherOctober 8, 2025graph_neural_networkprotein_evolutionprotein_fitness_prediction+4

    Compact protein fitness predictor that fuses within-family evolutionary profiles with inverse-folding logits for zero-shot variant effect prediction.

    Protein
    26Openness
  • TabPFN-Wide

    University of TübingenOctober 7, 2025biomarker_discoveryfoundation_modelgenomics+3

    Tabular foundation model adapted for extreme feature counts, enabling in-context prediction on wide omics tables with tens of thousands of features.

    DNA & GeneSingle-cell
    32Openness
  • DynamicsPLM

    11
    Technion – Israel Institute of Technology +1 otherOctober 6, 2025conformational_dynamicsenzyme_function_predictionlanguage_model+4

    Protein language model conditioned on ensembles of computed conformations, giving state-aware embeddings for interaction, localization, and function.

    Protein
    65Openness
  • SLAE

    7
    Stanford UniversityOctober 6, 2025all_atomautoencoderrepresentation_learning+2

    All-atom protein representation model that learns from each residue's strictly local atomic neighborhood, capturing side-chain geometry and chemistry.

    Protein
    20Openness
  • Chinese University of Hong Kong +1 otherOctober 3, 2025multimodalmutation_effect_predictionproteomics+3

    Structure-conditioned fine-tune of ESM2 for protein mutation-effect prediction, matching ESM3-level accuracy after roughly an hour of fine-tuning.

    Protein
    25Openness
  • Stockholm UniversityOctober 3, 2025de_novo_designgenerativepeptides+5

    GPCR structure prediction and peptide design model that generates linear and cyclic peptide agonists carrying noncanonical amino acids, zero-shot.

    Protein
    58Openness
  • PLMNovo

    113
    Duke UniversityOctober 3, 2025de_novo_peptide_sequencingmass_spectrometryprotein_sequencing+4

    De novo peptide sequencing model that aligns tandem mass spectra with protein language model embeddings through constrained optimization.

    Protein
    19Openness
  • Kanzi

    3832
    CaltechOctober 3, 2025autoencoderflow_matchinggenerative+4

    Flow-based protein structure tokenizer, a diffusion autoencoder replacing SE(3)-invariant components with global coordinates and standard attention.

    Protein
    63Openness
  • University of Texas at Austin +1 otherOctober 3, 2025de_novo_designdiffusionflow_matching+3

    Distilled few-step protein backbone generator that adapts Score Identity Distillation to Proteina for over 20x faster de novo structure sampling.

    Protein
    76Openness
  • FLOWR.root

    1373
    Pfizer +3 othersOctober 2, 2025binding_affinity_predictionde_novo_designflow_matching+4

    SE(3)-equivariant flow-matching model for pocket-aware 3D ligand generation, predicting binding affinity and confidence in the same network.

    Small moleculeProtein
    87Openness
  • Central South UniversityOctober 1, 2025cross_modality_translationfoundation_modelself_supervised

    Single-cell foundation model with a Hyena backbone that translates across omics layers, predicting protein abundance from transcriptomes zero-shot.

    Single-cell
    76Openness
  • University of FloridaOctober 1, 2025binding_affinity_predictiondrug_discoverygraph_neural_network+4

    Geometric deep learning scoring function for protein-ligand binding affinity, pretrained on synthetic complexes and fine-tuned on PDBbind structures.

    ProteinSmall molecule
    71Openness
  • University of PennsylvaniaOctober 1, 2025batch_integrationcell_type_annotationfoundation_model+5

    Kidney-specialized single-cell foundation model trained across four mammalian species for zero-shot cell-type annotation and batch integration.

    Single-cellSpatial omics
    22Openness
  • Shanghai Jiao Tong UniversityOctober 1, 2025brain_age_predictionbrain_mridensenet+8

    Brain MRI foundation model pairing DenseNet and Vision Transformer backbones with mixture of experts for disease diagnosis and brain age prediction.

    Imaging
    8Openness