All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–48 of 84 filtered models
RNAGAN
1——Generative adversarial network trained on single-cell and bulk RNA-seq for sample stratification, marker analysis, and synthetic data generation.
Single-cell60OpennessCDS-BART
——9Coding-sequence foundation model for mRNA design, pretrained as a BART denoising encoder-decoder on mRNA from nine taxonomic groups.
RNA63OpennessPerturbGen
25——Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cell trajectories over time.
Single-cell72OpennessCellPace
———Temporal diffusion framework for single-cell developmental dynamics, interpolating and forecasting cell states from irregularly sampled time series.
Single-cell9OpennessBOTANIC-0
—1177Plant genomic foundation models from 0.1B to 1B parameters, pretrained on 43 phylogenetically diverse plant genomes for variant effect prediction.
DNA & Gene19OpennessPerturbDiff
547—Diffusion model predicting single-cell responses to genetic or drug perturbations, generating over distributions to capture population variability.
Single-cell51OpennessSingle-cell foundation model applying discrete diffusion directly to scRNA-seq counts, generating unconditional and perturbation-conditioned profiles.
Single-cell10OpennessTransformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.
DNA & Gene10OpennessevoCancerGPT
———Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.
Single-cell11OpennessSTPAINTER
———University of Science and Technology of China +2 othersFebruary 13, 2026cancerdiffusionfoundation_model+4Pan-cancer pretrained diffusion model imputing genome-wide expression from sparse spatial transcriptomics panels, zero-shot and reference-free.
Spatial omicsSingle-cell4OpennessEVA
——89Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.
Single-cellRNAPathology27OpennessscDFM
447—Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.
Single-cell54OpennessscDiVa
—1—Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.
Single-cell6OpennessMoLF
———Pan-cancer model predicting spatial gene expression from H&E histology using conditional flow matching with a mixture-of-experts velocity field.
PathologySpatial omics9OpennessSAGE-FM
———Spatial transcriptomics foundation model built on a lightweight graph convolutional network and trained by masked central-spot prediction.
Spatial omicsSingle-cell10OpennessSingle-cell RNA-seq language model that treats cells as gene-expression tokens, synthesizing whole transcriptomes from tissue and disease metadata.
Single-cellSpatial omics2OpennessMultimodal architecture coupling pretrained DNA, RNA, and protein language models with directional cross-attention into one Virtual Cell Embedding.
DNA & GeneRNAProtein22OpennessOmniCell
—1—Transcriptomic foundation model pretrained on 67M single-cell and spatial profiles, modeling gene expression and inter-cellular dependencies.
Single-cellSpatial omics9OpennessGenoME
—1—Mixture-of-Experts generative model turning DNA sequence plus cell-type ATAC-seq into unified epigenomic, transcriptomic, and 3D chromatin profiles.
DNA & GeneSingle-cell8OpennessNucleotide Transformer v3 (NTv3)
901234.8KMulti-species genomics foundation model spanning representation learning, functional-track prediction, and sequence generation at 1 Mb context.
DNA & Gene25OpennessPlantBiMoE
8—6Plant genome foundation model pairing a bidirectional Mamba backbone with sparse Mixture-of-Experts, pretrained on 25.4B nucleotides from 42 species.
DNA & Gene53OpennessCellHermes
30276Single-cell foundation model adapting LLaMA-3.1-8B with LoRA, recasting transcriptomes and protein interaction networks as natural-language Q&A pairs.
Single-cellRNA55OpennessSpatial transcriptomics language model that reads tissue as spatial sentences to simulate cell profiles and run in silico perturbations.
Spatial omicsSingle-cell53Openness