Single-cell foundation model applying discrete diffusion directly to scRNA-seq counts, generating unconditional and perturbation-conditioned profiles.
Aqlaboratory / OpenFold Consortium / Lawrence Livermore National Laboratory / Seoul National University / Novo Nordisk / Amazon Web Services / Chan Zuckerberg Initiative / Absci / SandboxAQ / AMD / NVIDIA / University of Bristol / Pfizer
Released October 28, 2025
Open-source Apache-2.0 reproduction of AlphaFold3 that predicts all-atom structures of proteins, RNA, DNA, small molecules, and their complexes.
University of Bristol / Universidade de Brasília / Universidade Federal de Minas Gerais
Released April 23, 2025
Linear B-cell epitope prediction using phylogeny-aware fine-tuning of ESM embedders, with taxon-specific models for 19 pathogen groups.