All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 84 filtered models

  • AstraZenecaJune 29, 2026contrastive_learninggene_expressionhistology+2

    Histopathology-to-molecular alignment model that queries H&E slides with gene-set signatures to predict pathway activity without sequencing.

    PathologyRNA
    16Openness
  • Max Delbrück Center for Molecular MedicineJune 24, 2026gene_expressiongenerativerepresentation_learning+4

    Supervised variational autoencoder that learns a tissue-aware latent space for bulk RNA-seq, trained on harmonized TCGA, GTEx, and ARCHS4 data.

    RNA
    84Openness
  • Washington University in St. LouisJune 22, 2026cell_biologycell_type_annotationgene_expression+5

    Single-cell language model that prepends biomedical knowledge-graph tokens to cell sentences, grounding cell type annotation in pathway structure.

    Single-cellLanguage model
    23Openness
  • vBx-1.0

    Verge LabsJune 16, 2026contrastive_learningfoundation_modelgene_expression+5

    Multimodal foundation model for precision neurology that reconstructs a patient's molecular brain state from blood to predict disease progression.

    Single-cellDNA & Gene
    5Openness
  • TifBERT

    2
    York UniversityJune 11, 2026bertfoundation_modelgene_expression+5

    Bulk RNA-seq foundation model learning normalization-robust transcriptome representations via TF-IDF gene ordering and masked gene modeling.

    RNA
    17Openness
  • LDARNet

    41
    Independent ResearcherJune 3, 2026dnafoundation_modelgene_expression+6

    Genomic foundation model with 120M parameters that learns adaptive DNA token boundaries by dynamic chunking, not fixed k-mer or byte-pair tokens.

    DNA & Gene
    26Openness
  • SQUALL

    Peking UniversityJune 3, 2026biomarker_discoveryfoundation_modelgene_expression+6

    Multimodal foundation model pretrained on 1.76B histology and spatial transcriptomics spots, inferring molecular state from whole-slide images.

    PathologySpatial omics
    6Openness
  • TARIO-2

    NoetikJune 1, 2026foundation_modelgene_expressionhistology+4

    Tumor foundation model that infers whole-transcriptome and microenvironment signal from H&E slides, pretrained on paired spatial transcriptomics.

    PathologySpatial omics
    6Openness
  • TxFM

    2
    Recursion PharmaceuticalsMay 31, 2026autoencoderfoundation_modelgene_expression+4

    Transcriptomics foundation model from Recursion that masks and reconstructs RNA-seq gene expression counts to learn reusable sample embeddings.

    Single-cell
    12Openness
  • DanioDecima

    Biohub +1 otherMay 29, 2026cnnde_novo_designdna+7

    Zebrafish sequence-to-function model predicting cell-type-specific gene expression from DNA sequence across embryonic development.

    DNA & GeneSingle-cell
    22Openness
  • FlowTransOP

    MIT +2 othersMay 27, 2026autoencodercross_domain_translationcross_species+7

    Flow-matching framework that translates omics signatures across biological domains, such as mouse to human transcriptomics, without paired samples.

    Single-cell
    87Openness
  • ProtmRNA

    2
    Fudan University +2 othersMay 20, 2026codongene_expressionlanguage_model+7

    Codon-level mRNA language model adapted from ESM-2 650M by swapping amino-acid tokens for codon tokens, transferring protein knowledge to mRNA tasks.

    RNA
    11Openness
  • ConvergeCELL

    34
    Converge BioMay 7, 2026bulk_rna_seqcontrastive_learningdrug_discovery+5

    Virtual cell foundation model pretrained on over 23 million cells from 5,000 patient samples for drug target and biomarker discovery.

    Single-cell
    67Openness
  • DoFormer

    Columbia University +2 othersMay 4, 2026causal_inferencefoundation_modelgene_expression+3

    Causal multimodal transformer that embeds the do-operator in attention to predict single-cell gene expression under unseen genetic perturbations.

    Single-cell
    8Openness
  • scPert

    Zhejiang University School of MedicineApril 28, 2026drug_discoveryfoundation_modelgene_expression+4

    Multi-modal transformer fusing LLM gene embeddings with biological knowledge graphs to predict single-cell responses to genetic perturbations.

    Single-cell
    14Openness
  • HyperMap

    1
    University of California, San Diego +1 otherApril 27, 2026crisprdrug_discoveryfew_shot+7

    Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few measured seed perturbations.

    Single-cell
    11Openness
  • CellPulse

    Wuhan Institute of VirologyApril 24, 2026drug_discoveryfoundation_modelgene_expression+5

    Direction-aware foundation model trained on bulk RNA-seq differential-expression profiles to simulate coordinated gene dynamics in viral infection.

    Single-cellLanguage model
    4Openness
  • H2O

    Tencent AI for Life Science Lab +2 othersApril 24, 2026contrastive_learningfoundation_modelgene_expression+6

    Pathology foundation model that infers spatial transcriptomics and proteomics directly from routine H&E whole-slide images, with no spatial assay.

    PathologySpatial omics
    7Openness
  • Zhejiang Lab +1 otherApril 21, 2026chromatinchromatin_accessibilitydna+8

    Genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window and a 1.25B-parameter mixture-of-experts transformer.

    DNA & Gene
    90Openness
  • Deep-Plant

    1
    Colorado State University +1 otherApril 9, 2026chromatincnnenhancer_prediction+6

    Chromatin-informed foundation model predicting regulatory activity and chromatin state directly from plant genomic sequence in Arabidopsis and rice.

    DNA & Gene
    87Openness
  • PlantCAD2

    974.2K
    Cornell UniversityApril 3, 2026foundation_modelfunctional_annotationgene_expression+7

    Long-context plant DNA language model, 676M parameters on a Mamba2 backbone, pretrained on 65 angiosperm genomes for cross-species variant annotation.

    DNA & Gene
    69Openness
  • Cold Spring Harbor LaboratoryApril 1, 2026de_novo_designdiffusiongene_expression+5

    Discrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.

    DNA & Gene
    49Openness
  • CLOP-DiT

    Third Military Medical UniversityMarch 30, 2026contrastive_learningdata_augmentationdiffusion+7

    Generates single-cell transcriptomes from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.

    Single-cell
    10Openness
  • DAMO AcademyMarch 26, 2026diffusionfoundation_modelgene_expression+4

    Virtual cell model using masked discrete diffusion over the whole transcriptome to simulate scRNA-seq perturbation responses across tissues.

    Single-cell
    21Openness