All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 69 filtered models

  • SQUALL

    Peking UniversityJune 3, 2026biomarker_discoveryfoundation_modelgene_expression+6

    Multimodal foundation model pretrained on 1.76 billion paired histology-spatial transcriptomics spots, linking whole-slide images to spatial molecular programs.

    PathologySpatial omics
    6Openness
  • LDARNet

    1
    Independent ResearcherJune 3, 2026dnafoundation_modelgene_expression+6

    A 120M-parameter genomic foundation model that learns adaptive DNA token boundaries via H-Net-style dynamic chunking instead of fixed k-mer or byte-pair tokenization.

    DNA & Gene
    26Openness
  • miDGD

    Aarhus UniversityJune 2, 2026autoencoderdeep_generative_decodergene_expression+6

    A deep generative decoder that infers microRNA expression directly from bulk or single-cell mRNA gene expression via a shared mRNA/miRNA latent space.

    RNASingle-cell
    8Openness
  • TARIO-2

    NoetikJune 1, 2026foundation_modelgene_expressionhistology+4

    Multimodal tumor foundation model trained on paired H&E histology and spatial transcriptomics to infer whole-transcriptome and tumor-microenvironment signal from routine H&E alone.

    PathologySpatial omics
    6Openness
  • TxFM

    2
    Recursion PharmaceuticalsMay 31, 2026autoencoderfoundation_modelgene_expression+4

    A self-supervised masked autoencoder for RNA-seq count data, pretrained on 1.4M public samples to learn transferable transcriptomic representations without per-dataset re-training.

    Single-cell
    12Openness
  • DanioDecima

    Chan Zuckerberg BiohubMay 29, 2026cnnde_novo_designdna+7

    A zebrafish DNA sequence-to-function model predicting cell-type-specific single-cell expression across 85 cell-type x developmental-timepoint combinations during embryogenesis.

    DNA & GeneSingle-cell
    22Openness
  • FlowTransOP

    MIT +2 othersMay 27, 2026autoencodercross_domain_translationcross_species+7

    A constrained deep flow-matching framework for distributional translation of omics signatures across biological domains, such as mouse-to-human transcriptomics, without paired samples.

    Single-cell
    87Openness
  • ProtmRNA

    2
    Fudan University +2 othersMay 20, 2026codongene_expressionlanguage_model+7

    A cross-modal transfer-learning model that adapts the ESM-2 650M protein language model to mRNA analysis by swapping amino-acid tokens for codon tokens, applied to mRNA benchmarks without re-training.

    RNA
    11Openness
  • ConvergeCELL

    59
    Converge BioMay 7, 2026bulk_rna_seqcontrastive_learningdrug_discovery+5

    A virtual cell foundation model pretrained on 23M+ cells from 5,000 patient samples for drug target and biomarker discovery.

    Single-cell
    67Openness
  • DoFormer

    Columbia University +1 otherMay 4, 2026causal_inferencefoundation_modelgene_expression+3

    A causal multimodal Transformer that embeds the do-operator within attention to predict single-cell responses to gene perturbations, including unseen ones.

    Single-cell
    8Openness
  • scPert

    Zhejiang University School of MedicineApril 28, 2026drug_discoveryfoundation_modelgene_expression+4

    A multi-modal Transformer that fuses LLM gene embeddings with biological knowledge graphs to predict single-cell transcriptomic responses to genetic perturbations.

    Single-cell
    14Openness
  • HyperMap

    University of California San Diego +1 otherApril 27, 2026crisprdrug_discoveryfew_shot+7

    Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few seed perturbations, using one-eighth the parameters of typical single-cell foundation models.

    Single-cell
    11Openness
  • CellPulse

    Wuhan Institute of VirologyApril 24, 2026drug_discoveryfoundation_modelgene_expression+5

    A direction-aware foundation model trained on ~23M bulk RNA-seq differential-expression profiles that simulates coordinated gene dynamics in viral infection.

    Single-cellLanguage model
    4Openness
  • H2O

    Tencent AI for Life Science Lab +2 othersApril 24, 2026contrastive_learningfoundation_modelgene_expression+6

    A foundation model that predicts spatial transcriptomics and proteomics directly from routine H&E whole-slide images using a vision transformer aligned with a language model.

    PathologySpatial omics
    7Openness
  • Zhejiang Lab +1 otherApril 21, 2026chromatinchromatin_accessibilitydna+8

    A 1.25B-parameter Mixture-of-Experts genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window.

    DNA & Gene
    90Openness
  • Deep-Plant

    1
    Colorado State University +1 otherApril 9, 2026chromatincnnenhancer_prediction+6

    A supervised, chromatin-informed foundation model that predicts regulatory activity directly from plant genomic sequence in Arabidopsis and rice.

    DNA & Gene
    87Openness
  • PlantCAD2

    894
    Cornell UniversityApril 3, 2026foundation_modelfunctional_annotationgene_expression+7

    A long-context plant DNA language model (676M params, Mamba2) pretrained on 65 angiosperm genomes for cross-species functional annotation.

    DNA & Gene
    69Openness
  • Cold Spring Harbor LaboratoryApril 1, 2026de_novo_designdiffusiongene_expression+5

    Generative discrete-diffusion model that designs regulatory DNA with tunable activity and learns activity-predictive representations rivaling genomic language models.

    DNA & Gene
    49Openness
  • CLOP-DiT

    Third Military Medical UniversityMarch 30, 2026contrastive_learningdata_augmentationdiffusion+7

    Generates single-cell transcriptomic profiles from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.

    Single-cell
    10Openness
  • DAMO AcademyMarch 26, 2026diffusionfoundation_modelgene_expression+4

    A generative cellular world model that uses masked discrete diffusion to learn whole-transcriptome scRNA-seq distributions and simulate perturbation responses across tissues and species.

    Single-cell
    21Openness
  • RNAGAN

    1
    The University of Hong KongMarch 20, 2026cancercell_type_annotationdata_generation+5

    Multipurpose generative adversarial network trained once on single-cell and bulk RNA-seq to perform stratification, marker analysis, data generation, and vectorization.

    Single-cell
    60Openness
  • CDS-BART

    115
    MOGAM Institute for Biomedical ResearchMarch 12, 2026bartfoundation_modelgene_expression+5

    A BART-based foundation model for mRNA coding-sequence analysis, pretrained by denoising across nine taxonomic groups and fine-tunable for expression, stability, and riboswitch tasks.

    RNA
    63Openness
  • PerturbGen

    21
    Wellcome Sanger InstituteMarch 5, 2026cell_biologyfoundation_modelgene_expression+6

    Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cellular trajectories over time.

    Single-cell
    72Openness
  • CellPace

    McGill UniversityFebruary 26, 2026cell_biologydiffusiongene_expression+5

    A temporal diffusion-forcing generative framework for simulating, interpolating, and forecasting single-cell developmental dynamics from irregularly sampled time-series data.

    Single-cell
    9Openness