All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Applications

Architectures

Learning Paradigms

Biological Subjects

Showing 110 of 10 filtered models

DNA & Gene

AlphaGenome

Google DeepMind

Google DeepMind model that predicts thousands of functional genomic tracks at single base-pair resolution from megabase-scale DNA sequences.

1.9K50
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Single-cell

TranscriptFormer

Chan Zuckerberg Initiative

A generative cross-species foundation model for single-cell transcriptomics, trained on 112 million cells from 12 species spanning 1.5 billion years of evolution.

10826
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DNA & Gene

Borzoi

Calico Life Sciences

Deep learning model predicting cell-type-specific RNA-seq coverage at 32 bp resolution from 524 kb of DNA sequence, jointly modeling transcription, splicing, and polyadenylation.

236207
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Single-cell

GPTCelltype

Columbia University / Duke University

An R package that uses GPT-4 to annotate cell types in scRNA-seq data from marker genes, matching expert accuracy across hundreds of cell types and tissues.

224202
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Single-cell

scGPT

Bowang Lab

A generative pre-trained transformer for single-cell multi-omics, pretrained on 33 million human cells for cell annotation, batch correction, and perturbation prediction.

1.5K939
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Single-cell

scDisInFact

Zhang Lab

Disentangled VAE framework for joint batch correction, condition-key-gene detection, and perturbation prediction in multi-batch multi-condition scRNA-seq data.

1320
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DNA & Gene

seq2cells

GSK.ai

Transfer learning framework that predicts single-cell gene expression from ~200kb DNA sequences using Enformer embeddings and a lightweight MLP.

1215
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DNA & Gene

Nucleotide Transformer

InstaDeep

A family of DNA foundation models (500M–2.5B parameters) trained on 3,200+ human genomes and 850 species for genomic sequence understanding and variant effect prediction.

858173
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DNA & Gene

Enformer

Google DeepMind

Transformer model that predicts gene expression and regulatory activity from 200kb DNA sequences, capturing enhancer-promoter interactions up to 100kb away.

14.9K1.1K
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Single-cell

scVAE

Technical University of Denmark / University of Copenhagen

Variational autoencoder for single-cell RNA-seq that models raw count distributions directly, producing latent cell representations without normalization preprocessing.

89
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