All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–48 of 105 filtered models
CLIPepPI
2——Hebrew University of JerusalemMarch 20, 2026contrastive_learningpeptide_binding_predictionprotein_protein_interaction+5Contrastive dual-encoder model embedding protein domains and peptides in one space to predict domain-peptide binding specificity at proteome scale.
Protein50OpennessSELFormerMM
3——Multimodal molecular foundation model fusing SELFIES, 2D graphs, text, and knowledge graphs via contrastive pretraining for property prediction.
Small molecule55OpennessHorizyn-1
123—Dual-encoder contrastive model that retrieves enzymes for query reactions by matching reaction fingerprints to protein sequence embeddings.
ProteinSmall molecule21OpennessEEG-to-text foundation model that turns raw recordings into clinically grounded natural-language narratives instead of fixed-label classifications.
Biosignals18OpennessProtAlign
———Lawrence Livermore National LaboratoryMarch 6, 2026contrastive_learningcross_modal_retrievalembeddings+4Cross-modal protein encoder that aligns ESM-2 sequence embeddings with ProteinMPNN structure embeddings in a shared space for cross-modal retrieval.
Protein35OpennessCALM-1.0
—3—Contrastive antibody language model predicting antibody-antigen binding specificity from sequence with a dual-encoder, cross-attentive architecture.
Protein10OpennessMAP
———Shanghai Jiao Tong UniversityFebruary 25, 2026contrastive_learningdrug_response_predictiongraph_neural_network+6Knowledge-graph-grounded model that predicts single-cell transcriptomic responses to small molecules, with zero-shot prediction for unprofiled drugs.
Single-cellSmall molecule12OpennessEnzPlacer
———Enzyme function prediction model that uses contrastive learning to assign the first three EC digits to enzymes with functions unseen during training.
Protein59OpennessBioCLIP 2.5
77435.3KVision foundation model for the tree of life, scaling BioCLIP 2 to a ViT-H/14 backbone and more organism images for zero-shot species classification.
Imaging93OpennessNeuroVLM
8——Vision-language foundation model linking human brain activation maps and neuroscience text for text-to-brain and brain-to-text generation.
ImagingLanguage model74OpennessDecoderTCR
8——Masked language model for T-cell receptor and peptide-MHC binding prediction, with compositional pretraining and non-autoregressive decoding.
Protein56OpennessConGLUDe
———Johannes Kepler University LinzJanuary 14, 2026binding_site_predictioncontrastive_learningdrug_discovery+7Contrastive geometric model unifying structure- and ligand-based drug design for zero-shot virtual screening, target fishing, and pocket selection.
ProteinSmall molecule8OpennessOKR-CELL
———Cross-modal single-cell foundation model that aligns gene-expression profiles with LLM-enriched cell descriptions in a shared embedding space.
Single-cellLanguage model23OpennessMerlin
4531366.9K3D vision-language foundation model for abdominal CT, pretrained on scans, radiology reports, and EHR codes for zero-shot interpretation.
ImagingLanguage model54OpennessEXAONE Path 2.5
5280Pathology foundation model that aligns whole-slide images with genomic, epigenetic, and transcriptomic data for patient-level tumor representations.
PathologySpatial omics14OpennessCLEF
554—Single-lead ECG foundation model pretrained on 12-lead recordings, weighting contrastive pairs by clinical risk for cardiovascular risk prediction.
Biosignals62OpennessTEA
2443.7KProtein sequence encoder that maps ESM2 embeddings to a learned 20-letter alphabet for structure-quality remote homology detection at MMseqs2 speed.
Protein86OpennessSIGMMA
—1—Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.
PathologySpatial omics20OpennessAtacformer
28297Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.
Single-cellDNA & Gene32OpennessNyxBind
1—2Hong Kong University of Science and TechnologyOctober 21, 2025bertbinding_site_predictioncontrastive_learning+5Transcription factor binding site prediction model that refines a DNABERT-2 backbone with contrastive learning across diverse TFBS types.
DNA & Gene40OpennessCoLiPRI
—155.5KVision-language encoders for chest CT that align 3D volumes with radiology reports using contrastive, report-generation, and masked-image objectives.
Imaging60OpennessRADiAnce
———Retrieval-augmented latent diffusion model for protein binder design, retrieving interfaces in a shared latent space across peptides and antibodies.
Protein26Openness