All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 105 filtered models

  • HASSL

    2
    TUM.ai +3 othersJuly 5, 2026cell_biologycontrastive_learningfoundation_model+4

    Hierarchy-aware self-supervised model for single-cell microscopy that preserves morphological structure suppressed by imaging-modality confounders.

    ImagingSingle-cell
    37Openness
  • WattmaMod

    Shandong University +3 othersJuly 2, 2026contrastive_learningepitranscriptomicsfoundation_model+4

    RNA modification profiling from nanopore direct RNA-seq signal; self-supervised pretraining resolves 11 modification types and extends to new ones.

    RNABiosignals
    21Openness
  • AstraZenecaJune 29, 2026contrastive_learninggene_expressionhistology+2

    Histopathology-to-molecular alignment model that queries H&E slides with gene-set signatures to predict pathway activity without sequencing.

    PathologyRNA
    16Openness
  • PertOmni

    1
    Yale University +2 othersJune 26, 2026cell_biologycontrastive_learningdrug_gene_interaction+6

    Contrastive multimodal model for perturbation screens, aligning transcriptomic signatures with text and cell-painting image embeddings.

    Single-cellSmall molecule
    18Openness
  • Helmholtz MunichJune 22, 2026cell_biologycontrastive_learningfluorescence_microscopy+6

    Self-supervised 3D masked autoencoder for volumetric fluorescence microscopy, aligned to ESM2 embeddings to predict protein localization.

    ImagingSingle-cell
    71Openness
  • vBx-1.0

    Verge LabsJune 16, 2026contrastive_learningfoundation_modelgene_expression+5

    Multimodal foundation model for precision neurology that reconstructs a patient's molecular brain state from blood to predict disease progression.

    Single-cellDNA & Gene
    5Openness
  • SpineAgent

    6
    University of WashingtonJune 7, 2026contrastive_learningfoundation_modelimage_classification+8

    Multi-sequence spine MRI foundation model with DINOv3 encoders, supporting condition classification, pathology localization, and report generation.

    Imaging
    55Openness
  • tf-SFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+5

    Transcription factor-DNA binding specificity prediction from sequence, with a physics-derived dual-encoder trained by symmetric contrastive learning.

    DNA & Gene
    18Openness
  • drug-SFM

    1
    ETH ZurichJune 4, 2026contrastive_learningcross_modal_retrievaldrug_repurposing+8

    Specificity foundation model predicting small-molecule drug-target binding from sequence, scored as cross-modal retrieval without docking or assays.

    Small molecule
    16Openness
  • crisprSFM

    2
    ETH ZurichJune 4, 2026contrastive_learningcrisprcross_modal_retrieval+6

    CRISPR off-target prediction model that scores gRNA-DNA specificity from sequence, framing guide-target recognition as cross-modal retrieval.

    DNA & Gene
    19Openness
  • enzyme-SFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Enzyme-substrate specificity model that scores catalytic pairs from sequence with a physics-derived dual-encoder and a contrastive objective.

    Protein
    23Openness
  • mhcSFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Peptide-MHC binding specificity model that frames presentation as cross-modal retrieval, aligning peptide and MHC encoders by contrastive learning.

    Protein
    23Openness
  • mir-SFM

    2
    ETH ZurichJune 4, 2026contrastive_learningcross_modal_retrievaldual_encoder+6

    Foundation model that predicts microRNA-mRNA target specificity from sequence, using a dual-encoder trained with a symmetric contrastive objective.

    RNA
    25Openness
  • TESSERA

    5
    Weill Cornell MedicineJune 1, 2026cancer_genomicscell_type_annotationcontrastive_learning+5

    Self-supervised foundation model that embeds cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types for tumor subtyping.

    DNA & Gene
    28Openness
  • GenBloom

    3
    Helmholtz Munich +1 otherMay 28, 2026cell_type_annotationcontrastive_learningcytology+6

    Genetically aligned foundation model for blood smear cytology that links single-cell morphology to the chromosomal aberrations behind AML and APL.

    Pathology
    65Openness
  • C3P

    1
    University of TorontoMay 24, 2026bacterial_genomeco_regulated_gene_retrievalcontrastive_learning+8

    Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.

    DNA & Gene
    77Openness
  • MetFoundation

    Hong Kong Baptist UniversityMay 20, 2026aging_clockcontrastive_learningdisease_risk_prediction+6

    Metabolomic foundation model pretrained on UK Biobank NMR metabolite profiles, reused with a frozen backbone for aging, subtyping, and disease risk.

    Metabolomics
    7Openness
  • BRIDGE

    The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8

    Multi-organ foundation model aligning histology images with spatial-transcriptomics profiles for zero-shot expression and survival prediction.

    PathologySpatial omics
    31Openness
  • ConvergeCELL

    34
    Converge BioMay 7, 2026bulk_rna_seqcontrastive_learningdrug_discovery+5

    Virtual cell foundation model pretrained on over 23 million cells from 5,000 patient samples for drug target and biomarker discovery.

    Single-cell
    67Openness
  • ProtSent

    712
    Hebrew University of Jerusalem +1 otherMay 7, 2026contrastive_learningembeddingsproteomics+4

    Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.

    Protein
    87Openness
  • University of KentuckyMay 4, 2026contrastive_learningintrinsic_disorder_predictionmolecular_dynamics+6

    Protein language model aligning ESM sequence embeddings with molecular dynamics trajectories for zero-shot mutation effect and stability prediction.

    Protein
    10Openness
  • H2O

    Tencent AI for Life Science Lab +2 othersApril 24, 2026contrastive_learningfoundation_modelgene_expression+6

    Pathology foundation model that infers spatial transcriptomics and proteomics directly from routine H&E whole-slide images, with no spatial assay.

    PathologySpatial omics
    7Openness
  • DIA-CLIP

    AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6

    Contrastive dual-encoder model for DIA proteomics, embedding peptides and spectra in a shared space for zero-shot peptide-spectrum matching.

    Protein
    11Openness
  • CLOP-DiT

    Third Military Medical UniversityMarch 30, 2026contrastive_learningdata_augmentationdiffusion+7

    Generates single-cell transcriptomes from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.

    Single-cell
    10Openness