All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 97120 of 125 filtered models

  • SCimilarity

    258125
    GenentechNovember 20, 2024autoencodercell_type_annotationcontrastive_learning+3

    Single-cell foundation model trained by metric learning to embed scRNA-seq profiles for cell type annotation and similarity search in cell atlases.

    Single-cell
    78Openness
  • scGenePT

    3113
    Chan Zuckerberg InitiativeOctober 28, 2024foundation_modelgene_expressionmultimodal+4

    Single-cell perturbation prediction model that adds gene-level language embeddings from NCBI, UniProt, and Gene Ontology to scGPT representations.

    Single-cell
    90Openness
  • MAMMAL

    11891K
    IBM ResearchOctober 28, 2024cell_type_annotationdrug_discoveryfoundation_model+7

    Multi-modal, multi-task biological foundation model trained on 2 billion samples spanning proteins, small molecules, and single-cell gene expression.

    ProteinSmall moleculeSingle-cell
    74Openness
  • GeneCompass

    119137
    Chinese Academy of SciencesOctober 8, 2024cross_speciesfoundation_modelregulatory_genomics+1

    Knowledge-informed cross-species foundation model pre-trained on 101 million human and mouse single-cell transcriptomes to decipher gene regulation.

    Single-cell
    32Openness
  • PINNACLE

    1095
    Harvard UniversityAugust 1, 2024foundation_modelgraph_neural_networkprotein_protein_interaction+1

    Geometric deep learning model generating context-aware protein representations across 156 cell-type contexts from a multi-organ single-cell atlas.

    Single-cell
    83Openness
  • scPRINT

    15555
    Institut PasteurJuly 29, 2024foundation_modelgene_networktransformer

    Single-cell foundation model pre-trained on 50 million cells for gene network inference, denoising, and cell type prediction.

    Single-cell
    90Openness
  • Yale UniversityJuly 21, 2024cell_type_annotationfoundation_modellanguage_model

    Framework turning single-cell expression profiles into ranked gene-name sequences, letting off-the-shelf language models generate and annotate cells.

    Single-cell
    74Openness
  • Chan Zuckerberg InitiativeJuly 1, 2024autoencodercell_type_annotationde_novo_design+6

    Variational autoencoder pretrained on 74 million human single-cell transcriptomes from the CELLxGENE Census for batch correction and cell typing.

    Single-cell
    96Openness
  • CellFM

    11078
    Sun Yat-sen UniversityJune 6, 2024cell_biologyfoundation_modeltranscriptomics+1

    Single-cell foundation model with 800M parameters trained on ~100 million human cells, for annotation, perturbation prediction, and gene analysis.

    Single-cell
    26Openness
  • scFoundation

    423596
    Biomap ResearchJune 6, 2024foundation_modeltranscriptomics

    Single-cell transcriptomics foundation model with 100 million parameters, pretrained on over 50 million human scRNA-seq profiles for cell embeddings.

    Single-cell
    57Openness
  • CellPLM

    10497
    OmicsMLMay 1, 2024cell_biologyfoundation_modellanguage_model+1

    Single-cell foundation model that treats cells as tokens and tissues as sentences, encoding cell-cell relationships across 85M parameters.

    Single-cell
    50Openness
  • Nicheformer

    167144945
    Helmholtz Munich +1 otherApril 17, 2024foundation_modelspatial_transcriptomicstranscriptomics+1

    Transformer foundation model pretrained on 110M single-cell and spatial transcriptomics profiles, transferring spatial context to dissociated cells.

    Single-cell
    87Openness
  • scGPT

    1.6K1.2K
    Bowang LabFebruary 26, 2024foundation_modelgene_expressionperturbation+1

    Generative pretrained transformer trained on 33 million human cells for single-cell annotation, batch correction, and perturbation prediction.

    Single-cell
    82Openness
  • ZJUNlpFebruary 13, 2024foundation_modelnatural_language

    Conversational T5-based framework that turns scRNA-seq data into cell sentences for cell type annotation and drug sensitivity prediction.

    Single-cellLanguage model
    19Openness
  • scMulan

    626
    Tsinghua UniversityJanuary 29, 2024foundation_modelgenerativelanguage_model+1

    Generative language model for single-cell transcriptomics with 368M parameters, unifying cell type annotation, batch integration, and cell generation.

    Single-cell
    48Openness
  • IMPA

    2657
    Theis LabJanuary 8, 2024autoencodercell_biologydrug_discovery+5

    Generative image perturbation autoencoder predicting cellular morphological responses to chemical and genetic perturbations from control images.

    Single-cell
    53Openness
  • scPROTEIN

    5533
    TencentAILabHealthcareJanuary 1, 2024foundation_model

    Deep graph contrastive learning framework for single-cell proteomics embedding, handling peptide uncertainty, missingness, and batch effects.

    Single-cell
    86Openness
  • Tsinghua UniversityJanuary 1, 2024diffusionfoundation_modelgenerative

    Diffusion model for synthesizing single-cell RNA-seq data, with guided generation of specific cell types, rare cells, and developmental trajectories.

    Single-cell
    60Openness
  • scPML

    1213
    Shenzhen UniversityDecember 14, 2023cell_type_annotationgraph_neural_network

    Cell type annotation for single-cell RNA-seq that builds a graph per signaling pathway, learning across pathway views with graph neural networks.

    Single-cell
    56Openness
  • UCE

    312174
    Stanford UniversityNovember 29, 2023cross_speciesfoundation_modeltransformer+1

    Single-cell foundation model producing species-agnostic cell embeddings by representing genes through frozen ESM-2 protein language model embeddings.

    Single-cell
    65Openness
  • GEARS

    386376
    SNAP (Stanford)August 17, 2023crispr_screen_analysisgenetic_interaction_predictiongenomics+5

    Perturbation prediction model that forecasts transcriptional responses to multi-gene CRISPR perturbations from scRNA-seq and a gene-gene graph.

    Single-cell
    68Openness
  • XA4C

    3
    University of CalgaryJuly 17, 2023autoencodercell_type_annotationgene_expression+3

    Explainable autoencoder for transcriptome analysis that uses SHAP attribution on latent variables to identify critical genes driving gene expression.

    Single-cell
    58Openness
  • TencentAILabHealthcareJuly 4, 2023cross_modality_translationfoundation_modelgenerative+5

    Generative transformer that translates single-cell transcriptomes into proteomes, inferring missing protein abundance from RNA expression alone.

    Single-cell
    33Openness
  • Geneformer

    1.1K4.8K
    Broad Institute +1 otherMay 31, 2023foundation_modelgene_networktranscriptomics+1

    Single-cell foundation model pretrained on about 30 million human transcriptomes, using rank-value encoding for context-aware gene network inference.

    Single-cell
    96Openness