All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 7396 of 125 filtered models

  • Tahoe-x1

    1591539
    Tahoe TherapeuticsOctober 23, 2025cancercell_type_annotationdrug_discovery+7

    Perturbation-trained single-cell foundation models (up to 3B parameters) that jointly model genes, cells, and compounds for precision oncology tasks.

    Single-cellSmall molecule
    95Openness
  • CellTok

    Tsinghua UniversityOctober 22, 2025autoencodercell_cell_communicationcell_type_annotation+7

    Multimodal LLM that tokenizes single cells into discrete VQ-VAE codebook tokens, letting one model reason jointly over transcriptomes and text.

    Single-cellLanguage model
    20Openness
  • scConcept

    378103
    Theis Lab +1 otherOctober 14, 2025contrastive_learningself_supervisedsingle_cell+2

    Single-cell foundation model learning technology-agnostic cell embeddings by contrasting cell views rather than reconstructing gene expression counts.

    Single-cell
    64Openness
  • GeneJEPA

    355
    Biostate AIOctober 14, 2025cell_type_annotationfoundation_modelperturbation_prediction+2

    Self-supervised single-cell foundation model that predicts masked gene embeddings in latent space using a joint-embedding predictive architecture.

    Single-cell
    44Openness
  • University of TübingenOctober 7, 2025biomarker_discoveryfoundation_modelgenomics+3

    Tabular foundation model adapted for extreme feature counts, enabling in-context prediction on wide omics tables with tens of thousands of features.

    DNA & GeneSingle-cell
    32Openness
  • Central South UniversityOctober 1, 2025cross_modality_translationfoundation_modelself_supervised

    Single-cell foundation model with a Hyena backbone that translates across omics layers, predicting protein abundance from transcriptomes zero-shot.

    Single-cell
    76Openness
  • University of PennsylvaniaOctober 1, 2025batch_integrationcell_type_annotationfoundation_model+5

    Kidney-specialized single-cell foundation model trained across four mammalian species for zero-shot cell-type annotation and batch integration.

    Single-cellSpatial omics
    22Openness
  • BioVERSE

    2
    IBM ResearchOctober 1, 2025cell_biologycell_type_annotationcross_modal_question_answering+5

    Multimodal biomedical framework aligning frozen single-cell and protein model encoders to an LLM's embedding space for zero-shot reasoning.

    Language modelSingle-cellProtein
    23Openness
  • Institute of Science and Technology Austria +1 otherOctober 1, 2025cell_paintingdiffusiongenerative+4

    Diffusion model for multichannel fluorescent cell microscopy, generating morphologically plausible images aligned to OpenPhenom phenotypic embeddings.

    ImagingSingle-cell
    22Openness
  • Scooby

    6912463
    Technical University of Munich +4 othersOctober 1, 2025chromatinchromatin_accessibility_predictionconvolutional_neural_network+5

    Predicts single-cell scRNA-seq coverage and scATAC-seq insertion profiles from DNA sequence, adapting the Borzoi trunk with a cell-specific decoder.

    Single-cell
    70Openness
  • scYeast

    51
    Shanghai Jiao Tong UniversityAugust 20, 2025cell_type_annotationfoundation_modeltransformer+1

    Single-cell foundation model for yeast that injects regulatory network priors into transformer attention for zero-shot and fine-tuned analysis.

    Single-cell
    68Openness
  • GREmLN

    38
    Chan Zuckerberg Initiative +2 othersJuly 9, 2025cell_type_annotationchromatinfoundation_model+6

    Single-cell transcriptomics foundation model that encodes gene regulatory network structure into self-attention through graph signal processing.

    Single-cell
    80Openness
  • MNCN-CSICJuly 9, 2025bertembeddingsfoundation_model+4

    Zebrafish single-cell foundation model built on the Geneformer framework, producing frozen gene and cell embeddings for developmental analysis.

    Single-cell
    46Openness
  • MORPH

    156
    Broad Institute +1 otherJuly 2, 2025attentioncell_paintingfoundation_model+5

    Single-cell perturbation-response model that predicts transcriptomic and imaging outcomes of unseen genetic perturbations via a VAE with attention.

    Single-cellImaging
    7Openness
  • STATE

    623117250
    Arc InstituteJune 27, 2025drug_discoveryfoundation_modelgene_expression+4

    Virtual cell transformer that predicts how cells respond to genetic, chemical, or signaling perturbations, generalizing to unseen cellular contexts.

    Single-cell
    21Openness
  • Chan Zuckerberg InitiativeApril 29, 2025cell_type_annotationcross_speciesdisease_prediction+6

    Generative single-cell foundation model trained on 112 million cells from 12 species, autoregressively modeling gene identities and expression counts.

    Single-cell
    67Openness
  • Shusi

    11
    Zhejiang UniversityApril 27, 2025cancerfoundation_modelgraph_neural_network+3

    Single-cell foundation model inferring context-specific protein-protein interactions from cancer transcriptomes via a variational graph autoencoder.

    Single-cellProtein
    20Openness
  • mLLMCelltype

    65310
    Texas A&M UniversityApril 17, 2025cell_type_annotationlanguage_model

    Multi-LLM consensus framework for automated cell type annotation in scRNA-seq data, outperforming prior methods by ~15% in mean accuracy.

    Single-cell
    37Openness
  • scPRINT

    15555
    Institut Pasteur +1 otherApril 16, 2025foundation_modelgene_network

    Single-cell foundation model pre-trained on 50 million cells that infers cell-specific gene regulatory networks from transformer attention matrices.

    Single-cell
    78Openness
  • TEDDY

    9
    Merck & Co.March 5, 2025cell_type_annotationdisease_classificationfoundation_model+3

    Single-cell RNA-seq foundation models combining masked modeling with ontology supervision to classify cell states across unseen donors and diseases.

    Single-cell
    46Openness
  • Tsinghua UniversityFebruary 27, 2025cross_attentiondata_generationdiffusion+4

    Latent diffusion model for single-cell multi-omics generation and modality translation, with gradient-based inference of gene regulatory networks.

    Single-cell
    85Openness
  • Guangzhou Medical University +1 otherFebruary 23, 2025cell_type_annotationcross_attentiondna_methylation+5

    Single-cell DNA methylation foundation model capturing genome-wide CpG dependencies in whole-genome bisulfite sequencing across tissues and species.

    Single-cellDNA & Gene
    78Openness
  • Tahoe-100M-SCVI

    1.7K123
    Tahoe TherapeuticsFebruary 20, 2025autoencodercancerembeddings+6

    scVI variational autoencoder trained on the Tahoe-100M drug-perturbation atlas, giving a 10-dimensional embedding of treated cancer cell states.

    Single-cell
    93Openness
  • AIDO.Cell

    16817108
    genbio.aiNovember 28, 2024bertcell_biologycell_type_annotation+7

    Single-cell RNA-seq foundation model pretrained on 50 million human cells, encoding the full transcriptome for annotation and perturbation modeling.

    Single-cell
    29Openness