All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 73–96 of 125 filtered models
Tahoe-x1
1591539Perturbation-trained single-cell foundation models (up to 3B parameters) that jointly model genes, cells, and compounds for precision oncology tasks.
Single-cellSmall molecule95OpennessCellTok
———Multimodal LLM that tokenizes single cells into discrete VQ-VAE codebook tokens, letting one model reason jointly over transcriptomes and text.
Single-cellLanguage model20OpennessGeneJEPA
355—Self-supervised single-cell foundation model that predicts masked gene embeddings in latent space using a joint-embedding predictive architecture.
Single-cell44OpennessTabPFN-Wide
—7—Tabular foundation model adapted for extreme feature counts, enabling in-context prediction on wide omics tables with tens of thousands of features.
DNA & GeneSingle-cell32OpennessscLinguist
91—Single-cell foundation model with a Hyena backbone that translates across omics layers, predicting protein abundance from transcriptomes zero-shot.
Single-cell76OpennessKidney-specialized single-cell foundation model trained across four mammalian species for zero-shot cell-type annotation and batch integration.
Single-cellSpatial omics22OpennessBioVERSE
—2—Multimodal biomedical framework aligning frozen single-cell and protein model encoders to an LLM's embedding space for zero-shot reasoning.
Language modelSingle-cellProtein23OpennessMorphGen
74—Institute of Science and Technology Austria +1 otherOctober 1, 2025cell_paintingdiffusiongenerative+4Diffusion model for multichannel fluorescent cell microscopy, generating morphologically plausible images aligned to OpenPhenom phenotypic embeddings.
ImagingSingle-cell22OpennessScooby
6912463Technical University of Munich +4 othersOctober 1, 2025chromatinchromatin_accessibility_predictionconvolutional_neural_network+5Predicts single-cell scRNA-seq coverage and scATAC-seq insertion profiles from DNA sequence, adapting the Borzoi trunk with a cell-specific decoder.
Single-cell70OpennessscYeast
51—Single-cell foundation model for yeast that injects regulatory network priors into transformer attention for zero-shot and fine-tuned analysis.
Single-cell68OpennessGREmLN
38——Single-cell transcriptomics foundation model that encodes gene regulatory network structure into self-attention through graph signal processing.
Single-cell80OpennessZebraformer
—1—Zebrafish single-cell foundation model built on the Geneformer framework, producing frozen gene and cell embeddings for developmental analysis.
Single-cell46OpennessMORPH
156—Single-cell perturbation-response model that predicts transcriptomic and imaging outcomes of unseen genetic perturbations via a VAE with attention.
Single-cellImaging7OpennessSTATE
623117250Virtual cell transformer that predicts how cells respond to genetic, chemical, or signaling perturbations, generalizing to unseen cellular contexts.
Single-cell21OpennessTranscriptFormer
15736—Generative single-cell foundation model trained on 112 million cells from 12 species, autoregressively modeling gene identities and expression counts.
Single-cell67OpennessShusi
11—Single-cell foundation model inferring context-specific protein-protein interactions from cancer transcriptomes via a variational graph autoencoder.
Single-cellProtein20OpennessmLLMCelltype
65310—Multi-LLM consensus framework for automated cell type annotation in scRNA-seq data, outperforming prior methods by ~15% in mean accuracy.
Single-cell37OpennessscPRINT
15555—Single-cell foundation model pre-trained on 50 million cells that infers cell-specific gene regulatory networks from transformer attention matrices.
Single-cell78OpennessTEDDY
—9—Single-cell RNA-seq foundation models combining masked modeling with ontology supervision to classify cell states across unseen donors and diseases.
Single-cell46OpennessscDiffusion-X
404—Latent diffusion model for single-cell multi-omics generation and modality translation, with gradient-based inference of gene regulatory networks.
Single-cell85OpennessscDNAm-GPT
202—Guangzhou Medical University +1 otherFebruary 23, 2025cell_type_annotationcross_attentiondna_methylation+5Single-cell DNA methylation foundation model capturing genome-wide CpG dependencies in whole-genome bisulfite sequencing across tissues and species.
Single-cellDNA & Gene78OpennessTahoe-100M-SCVI
1.7K123—scVI variational autoencoder trained on the Tahoe-100M drug-perturbation atlas, giving a 10-dimensional embedding of treated cancer cell states.
Single-cell93Openness