Arc Institute
An independent nonprofit research institute in Palo Alto pairing curiosity-driven biology with AI to understand and treat complex human disease.
Models (8)
Generative pipeline for epitope-targeted de novo antibody (nanobody) CDR design that yields nanomolar binders from only dozens of designs per antigen.
Multimodal reasoning LLM for protein function prediction, fusing protein language model embeddings to emit interpretable GO-term reasoning traces.
Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.
Single-cell foundation model using tabular attention over context cells to predict responses to arbitrary perturbations without fine-tuning.
Virtual cell transformer that predicts how cells respond to genetic, chemical, or signaling perturbations, generalizing to unseen cellular contexts.
Codon-resolution language models trained on 130 million coding sequences from 20,000 species, learning codon rules for translation and mRNA stability.
Genomic foundation model trained on 9.3 trillion DNA base pairs across all domains of life, with 40B parameters and a 1-million-token context.
Genomic foundation model with 7B parameters that models prokaryotic DNA, RNA, and protein at single-nucleotide resolution over a 131k-token context.