All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 73–96 of 518 filtered models
SE(3)-invariant masked autoencoder that learns protein fold representations from AlphaFold-DB structures, supporting zero-shot fold classification.
Protein78OpennessBio-BLIP
———Multimodal Q-former that fuses DNA sequence, gene context, protein function, and text for zero-shot variant interpretation with a frozen LLM.
DNA & GeneLanguage model23OpennessProtLiD
6——370M-parameter ligand-conditioned discrete diffusion model that co-designs protein sequence and structure under explicit small-molecule constraints.
Protein5OpennessSpaRank
———Spatial transcriptomics deconvolution foundation model whose rank-based spot encoding transfers across tissues and platforms without retraining.
Spatial omics8OpennessMuseDrift
———Conditional discrete diffusion model for protein variant generation, with a calibrated identity dial controlling drift from a wild-type sequence.
Protein12OpennessOmniGene-4
—1—Unified bio-language Mixture-of-Experts model spanning DNA, protein sequence and structure, and biological text across eight task families.
Language modelDNA & GeneProtein7OpennessFiberLM
———Transformer tractography model for mouse-brain diffusion MRI, guided by axonal priors learned from Allen Mouse Brain Connectivity Atlas streamlines.
Imaging8OpennessSusagi
8—4Microbiome world model that treats a community as a set of taxa, scoring how well each member fits and predicting community dynamics zero-shot.
DNA & Gene48OpennessBRIDGE
———The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8Multi-organ foundation model aligning histology images with spatial-transcriptomics profiles for zero-shot expression and survival prediction.
PathologySpatial omics31OpennessGoForth
———RNA inverse-folding language model that designs nucleotide sequences satisfying a target secondary structure, fixed bases, and coding constraints.
RNA63OpennessConvergeCELL
——34Virtual cell foundation model pretrained on over 23 million cells from 5,000 patient samples for drug target and biomarker discovery.
Single-cell67OpennessMochiDiff
———Discrete diffusion model for conditional antibody sequence design with germline-absorbing noising that focuses learning on somatic variation.
Protein8OpennessProtSent
7—12Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.
Protein87OpennessWaypoint
———Microbiome foundation models that treat microbial community composition as a language, enabling zero- and few-shot transfer across prediction tasks.
DNA & Gene23Opennesssm_protgpt2
——7Three fixed ProtGPT2 fine-tunes specialized for metalloprotein generation, trained on ProteinMPNN-derived synthetic sequences.
Protein38Openness- University of KentuckyMay 4, 2026contrastive_learningintrinsic_disorder_predictionmolecular_dynamics+6
Protein language model aligning ESM sequence embeddings with molecular dynamics trajectories for zero-shot mutation effect and stability prediction.
Protein10Openness DoFormer
———Causal multimodal transformer that embeds the do-operator in attention to predict single-cell gene expression under unseen genetic perturbations.
Single-cell8OpennessProteo-R1
6453.2KReasoning-guided foundation model for de novo antibody CDR design, pairing a multimodal LLM understanding expert with a Boltz-1 diffusion expert.
Protein53OpennessCodeFP
———Co-generative protein language model decoding sequence and structure tokens together from GO functional annotations for de novo protein design.
Protein17OpennessCarbon
200—6.4KAutoregressive DNA foundation model for variant effect prediction, using 6-mer tokenization to match Evo2-7B win rates at far higher throughput.
DNA & Gene93OpennessCoMole
———Motif-aware graph diffusion model for controllable molecular generation that adapts to unseen properties by learning a lightweight task embedding.
Small molecule23OpennessPhoenix
———Virtual spatial transcriptomics foundation model predicting pan-cancer, spatially-resolved single-cell gene expression from H&E histology slides.
PathologySpatial omics8OpennessscPert
———Multi-modal transformer fusing LLM gene embeddings with biological knowledge graphs to predict single-cell responses to genetic perturbations.
Single-cell14OpennessHyperMap
—1—Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few measured seed perturbations.
Single-cell11Openness