All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 7396 of 518 filtered models

  • ETH ZurichMay 18, 2026autoencoderfold_classificationfoundation_model+5

    SE(3)-invariant masked autoencoder that learns protein fold representations from AlphaFold-DB structures, supporting zero-shot fold classification.

    Protein
    78Openness
  • Bio-BLIP

    Stanford UniversityMay 15, 2026foundation_modelgenomicsmendelian_disease+7

    Multimodal Q-former that fuses DNA sequence, gene context, protein function, and text for zero-shot variant interpretation with a frozen LLM.

    DNA & GeneLanguage model
    23Openness
  • ProtLiD

    6
    National University of SingaporeMay 15, 2026de_novo_designdiffusiongenerative+6

    370M-parameter ligand-conditioned discrete diffusion model that co-designs protein sequence and structure under explicit small-molecule constraints.

    Protein
    5Openness
  • SpaRank

    Guangxi UniversityMay 13, 2026foundation_modelmultimodalspatial_transcriptomics+2

    Spatial transcriptomics deconvolution foundation model whose rank-based spot encoding transfers across tissues and platforms without retraining.

    Spatial omics
    8Openness
  • MuseDrift

    University of Florida +1 otherMay 12, 2026de_novo_designdiffusiongenerative+3

    Conditional discrete diffusion model for protein variant generation, with a calibrated identity dial controlling drift from a wild-type sequence.

    Protein
    12Openness
  • OmniGene-4

    1
    Huazhong University of Science and TechnologyMay 12, 2026dnafoundation_modelinstruction_following+7

    Unified bio-language Mixture-of-Experts model spanning DNA, protein sequence and structure, and biological text across eight task families.

    Language modelDNA & GeneProtein
    7Openness
  • FiberLM

    NYU Grossman School of MedicineMay 11, 2026connectomicsdiffusion_mriself_supervised+3

    Transformer tractography model for mouse-brain diffusion MRI, guided by axonal priors learned from Allen Mouse Brain Connectivity Atlas streamlines.

    Imaging
    8Openness
  • Susagi

    84
    University of ZurichMay 11, 2026denoisingmetagenomicsmicrobiome+4

    Microbiome world model that treats a community as a set of taxa, scoring how well each member fits and predicting community dynamics zero-shot.

    DNA & Gene
    48Openness
  • BRIDGE

    The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8

    Multi-organ foundation model aligning histology images with spatial-transcriptomics profiles for zero-shot expression and survival prediction.

    PathologySpatial omics
    31Openness
  • GoForth

    University of California, BerkeleyMay 8, 2026encoder_decodergenerativeinverse_folding+5

    RNA inverse-folding language model that designs nucleotide sequences satisfying a target secondary structure, fixed bases, and coding constraints.

    RNA
    63Openness
  • ConvergeCELL

    34
    Converge BioMay 7, 2026bulk_rna_seqcontrastive_learningdrug_discovery+5

    Virtual cell foundation model pretrained on over 23 million cells from 5,000 patient samples for drug target and biomarker discovery.

    Single-cell
    67Openness
  • MochiDiff

    University of Washington +1 otherMay 7, 2026antibodyantibody_designde_novo_design+6

    Discrete diffusion model for conditional antibody sequence design with germline-absorbing noising that focuses learning on somatic variation.

    Protein
    8Openness
  • ProtSent

    712
    Hebrew University of Jerusalem +1 otherMay 7, 2026contrastive_learningembeddingsproteomics+4

    Protein sequence embedding model, contrastively fine-tuned from ESM-2, that places functionally and structurally related proteins close together.

    Protein
    87Openness
  • Waypoint

    Outpost BioMay 6, 2026foundation_modelgptmetagenomics+5

    Microbiome foundation models that treat microbial community composition as a language, enabling zero- and few-shot transfer across prediction tasks.

    DNA & Gene
    23Openness
  • University of Naples Federico II +1 otherMay 5, 2026de_novo_designgenerativeprotein_design+2

    Three fixed ProtGPT2 fine-tunes specialized for metalloprotein generation, trained on ProteinMPNN-derived synthetic sequences.

    Protein
    38Openness
  • University of KentuckyMay 4, 2026contrastive_learningintrinsic_disorder_predictionmolecular_dynamics+6

    Protein language model aligning ESM sequence embeddings with molecular dynamics trajectories for zero-shot mutation effect and stability prediction.

    Protein
    10Openness
  • DoFormer

    Columbia University +2 othersMay 4, 2026causal_inferencefoundation_modelgene_expression+3

    Causal multimodal transformer that embeds the do-operator in attention to predict single-cell gene expression under unseen genetic perturbations.

    Single-cell
    8Openness
  • Proteo-R1

    6453.2K
    Stanford University +3 othersMay 1, 2026antibodyde_novo_designdiffusion+5

    Reasoning-guided foundation model for de novo antibody CDR design, pairing a multimodal LLM understanding expert with a Boltz-1 diffusion expert.

    Protein
    53Openness
  • CodeFP

    PharMolix Inc. +1 otherMay 1, 2026de_novo_designgenerativelanguage_model+2

    Co-generative protein language model decoding sequence and structure tokens together from GO functional annotations for de novo protein design.

    Protein
    17Openness
  • Carbon

    2006.4K
    Hugging Face +2 othersMay 1, 2026dnafoundation_modelgenerative+3

    Autoregressive DNA foundation model for variant effect prediction, using 6-mer tokenization to match Evo2-7B win rates at far higher throughput.

    DNA & Gene
    93Openness
  • CoMole

    University of Notre DameMay 1, 2026de_novo_designdiffusiondrug_discovery+7

    Motif-aware graph diffusion model for controllable molecular generation that adapts to unseen properties by learning a lightweight task embedding.

    Small molecule
    23Openness
  • Phoenix

    Helmholtz Munich +1 otherApril 29, 2026cell_type_annotationflow_matchingfoundation_model+6

    Virtual spatial transcriptomics foundation model predicting pan-cancer, spatially-resolved single-cell gene expression from H&E histology slides.

    PathologySpatial omics
    8Openness
  • scPert

    Zhejiang University School of MedicineApril 28, 2026drug_discoveryfoundation_modelgene_expression+4

    Multi-modal transformer fusing LLM gene embeddings with biological knowledge graphs to predict single-cell responses to genetic perturbations.

    Single-cell
    14Openness
  • HyperMap

    1
    University of California, San Diego +1 otherApril 27, 2026crisprdrug_discoveryfew_shot+7

    Meta-learning framework that transfers perturbation responses across cell lines, donors, and drugs from a few measured seed perturbations.

    Single-cell
    11Openness