All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 7396 of 316 filtered models

  • ATOMICA

    3
    Harvard UniversityMarch 16, 2026binding_site_predictionfoundation_modelgraph_neural_network+6

    Geometric deep learning model that learns atomic-scale representations of molecular interfaces across proteins, small molecules, and nucleic acids.

    ProteinSmall moleculeRNA
    88Openness
  • MIT +1 otherMarch 16, 2026foundation_modelhistopathologymultimodal+3

    Multimodal foundation model integrating spatial transcriptomics, H&E histopathology, and pathway scores for single-cell niche discovery.

    Spatial omicsSingle-cellPathology
    71Openness
  • CDS-BART

    9
    MOGAM Institute for Biomedical ResearchMarch 12, 2026bartfoundation_modelgene_expression+5

    Coding-sequence foundation model for mRNA design, pretrained as a BART denoising encoder-decoder on mRNA from nine taxonomic groups.

    RNA
    63Openness
  • mnDINO

    Morgridge Institute for ResearchMarch 12, 2026cell_biologyfluorescence_microscopyfoundation_model+4

    Vision transformer trained with DINO self-supervision to segment micronuclei in DNA-stained fluorescence images across cell lines and microscopes.

    Imaging
    32Openness
  • PatchDNA

    2
    Relation TherapeuticsMarch 12, 2026dnafoundation_modelgenomics+4

    DNA language model that replaces fixed tokenization with conservation-guided patching, letting models up to 10x smaller match top genomic benchmarks.

    DNA & Gene
    33Openness
  • MIT +1 otherMarch 11, 2026cell_type_annotationfoundation_modelgene_expression_prediction+7

    Cell-centric microscopy foundation model that distills morphology and microenvironment views into a unified embedding for virtual spatial omics.

    Spatial omicsImagingPathology
    15Openness
  • National University of SingaporeMarch 10, 2026antibodybinding_affinity_predictionfoundation_model+6

    Paired-sequence protein language model that jointly encodes two interacting chains to predict interactions, binding affinity, and interface contacts.

    Protein
    27Openness
  • FishMamba-1

    11
    Institute of Hydrobiology, Chinese Academy of SciencesMarch 9, 2026dnafoundation_modelgenome_annotation+4

    Genomic foundation model for Cypriniformes fish, built on a Mamba-2 state space model with a 32 kb context window for long-range genome modeling.

    DNA & Gene
    50Openness
  • BacPT

    1
    University of FloridaMarch 7, 2026bacterial_genomicsenzyme_annotationfoundation_model+6

    Bacterial proteome foundation model that learns contextualized gene and whole-genome representations from tens of thousands of complete genomes.

    Protein
    10Openness
  • Popformer

    University of PennsylvaniaMarch 6, 2026foundation_modelgenomicspopulation_genetics+6

    Self-supervised transformer for population genetics, pretrained on 1000 Genomes data, that detects positive selection via haplotype-wise attention.

    DNA & Gene
    19Openness
  • PerturbGen

    25
    Wellcome Sanger InstituteMarch 5, 2026cell_biologyfoundation_modelgene_expression+6

    Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cell trajectories over time.

    Single-cell
    72Openness
  • D3LM

    142
    Renmin University of ChinaMarch 2, 2026diffusiondnafoundation_model+6

    DNA foundation model using masked discrete diffusion to unify bidirectional sequence understanding and de novo generation in one architecture.

    DNA & Gene
    58Openness
  • RigidSSL

    201
    Chinese University of Hong KongMarch 2, 2026conformational_ensemble_generationflow_matchinggenerative+5

    Self-supervised SE(3) geometric pretraining for protein backbone generators, improving designability, motif scaffolding, and conformational ensembles.

    Protein
    73Openness
  • MolX

    1
    Monash UniversityMarch 1, 2026antibody_drug_conjugate_designbinding_affinity_predictiondrug_discovery+10

    Graph-transformer foundation model pretrained on 3M protein pockets and 5M molecules as E(3)-equivariant graphs for protein-ligand representation.

    Protein
    11Openness
  • MultiPUFFIN

    NTNU +2 othersMarch 1, 2026drug_discoveryfoundation_modelgraph_neural_network+6

    Multimodal foundation model pretrained on ~500K unlabeled PubChem molecules that jointly predicts nine thermophysical properties of small molecules.

    Small molecule
    10Openness
  • ARCH3D

    University of MichiganFebruary 25, 20263d_genomechromatincontact_map_reconstruction+5

    Foundation model for 3D genome architecture, using masked locus modeling over genome-wide contact profiles to capture chromosome-scale organization.

    DNA & Gene
    19Openness
  • MAP

    Shanghai Jiao Tong UniversityFebruary 25, 2026contrastive_learningdrug_response_predictiongraph_neural_network+6

    Knowledge-graph-grounded model that predicts single-cell transcriptomic responses to small molecules, with zero-shot prediction for unprofiled drugs.

    Single-cellSmall molecule
    12Openness
  • BOTANIC-0

    1177
    Living ModelsFebruary 23, 2026dnafoundation_modelgene_expression+5

    Plant genomic foundation models from 0.1B to 1B parameters, pretrained on 43 phylogenetically diverse plant genomes for variant effect prediction.

    DNA & Gene
    19Openness
  • MACE-POLAR-1

    16
    University of CambridgeFebruary 23, 2026drug_discoveryequivariant_neural_networkfoundation_model+5

    Polarizable machine-learning interatomic potential extending MACE with long-range electrostatics, trained on 100M OMol25 DFT calculations.

    Small moleculeProtein
    19Openness
  • PEINT

    6
    UC BerkeleyFebruary 20, 2026evolutionary_simulationgenerativemolecular_evolution+4

    Protein evolution model that learns indel dynamics and epistasis from unaligned sequences, simulating trajectories that yield functional proteins.

    Protein
    11Openness
  • JEPA-DNA

    178
    NVIDIAFebruary 19, 2026dnafoundation_modelgenomics+5

    Genomic foundation model training framework whose joint-embedding predictive objective learns functional representations of masked DNA, not tokens.

    DNA & Gene
    54Openness
  • OncoBERT

    National Cancer InstituteFebruary 19, 2026bertlanguage_modeloncology+7

    BERT-style language model for somatic mutations, pretrained on cancer sequencing from 210,000+ patients for tumor subtyping and therapy response.

    DNA & Gene
    7Openness
  • CLM-X

    Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6

    Multimodal single-cell foundation model whose multiway Transformer jointly models scRNA-seq and scATAC-seq from RNA-only, ATAC-only, or paired inputs.

    Single-cell
    4Openness
  • Florida International UniversityFebruary 17, 2026cheminformaticsdebertafoundation_model+4

    SMILES molecular encoder on a DeBERTaV2 backbone, pretrained on 123M PubChem molecules with physicochemical and structural-similarity objectives.

    Small molecule
    25Openness