All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 257 filtered models
MethylSeqNet
———University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6Conditions a pretrained DNA sequence embedding on CpG methylation to predict gene regulation across cell types and alleles, generalizing zero-shot to imprinting, X-inactivation, and accessibility.
DNA & Gene18OpennessDaX
1——Pathology vision foundation model adapting DINOv3-style self-supervised learning to whole-slide histopathology across continuous magnifications and scales.
Pathology11OpennessLDARNet
—1—A 120M-parameter genomic foundation model that learns adaptive DNA token boundaries via H-Net-style dynamic chunking instead of fixed k-mer or byte-pair tokenization.
DNA & Gene26OpennessSQUALL
———Multimodal foundation model pretrained on 1.76 billion paired histology-spatial transcriptomics spots, linking whole-slide images to spatial molecular programs.
PathologySpatial omics6OpennessBrainGFM
173—A graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero/few-shot generalization to unseen disorders.
Biosignals16OpennessPepForge
4——A hierarchical three-stage cascade that generates chemically modified and macrocyclic peptides in HELM notation, supporting de novo design and constrained infilling.
ProteinSmall molecule94OpennessCryoProt
———Protein pretraining framework that learns representations directly from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.
ImagingProtein11OpennessTESSERA
5——Self-supervised foundation model that learns reusable representations of cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types.
DNA & Gene28OpennessTxFM
2——A self-supervised masked autoencoder for RNA-seq count data, pretrained on 1.4M public samples to learn transferable transcriptomic representations without per-dataset re-training.
Single-cell12OpennessGlucoFM
———Google Research +1 otherMay 29, 2026continuous_glucose_monitoringfoundation_modelglucose_forecasting+4A dual-stream self-supervised foundation model for continuous glucose monitoring data, separating slow physiological state from transient glucose events.
Biosignals11OpennessChreode
———University of North Carolina at Chapel Hill +2 othersMay 27, 2026cell_fate_predictioncrispr_perturbationdevelopmental_trajectory_modeling+8A cell world model pretrained on a 2.4M-cell mouse embryonic atlas that predicts one-step transcriptional state transitions and transfers to perturbation prediction.
Single-cell26OpennessGEARS
———University of Central Florida +2 othersMay 27, 2026cell_localizationdiffusion_modeldomain_adaptation+8Geometry-first generative framework that reconstructs single-cell spatial coordinates by integrating scRNA-seq with spatial transcriptomics, without cell-type labels.
Single-cell22OpennessOryzaG3
———A 700M-parameter DNA language model pretrained on the rice pangenome, built as a reusable foundation model for crop genomics and molecular breeding.
DNA & Gene19Openness- Hong Kong University of Science and Technology +9 othersMay 25, 2026clinical_decision_supportfoundation_modellung_tissue+7
A subspecialty lung-pathology foundation model, fine-tuned from Virchow2 and prospectively validated across 32 clinical tasks spanning the lung diagnostic workflow.
Pathology5Openness C3P
———Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.
DNA & Gene77OpennessD2D
———Vrije Universiteit Brussel +1 otherMay 22, 2026binding_region_predictionepistasisintrinsically_disordered_regions+5Combines the ProtT5-XL protein language model with protein-specific evolutionary constraints to predict mutational effects on stability, binding, and epistasis—largely zero-shot.
Protein29OpennessGenos-m
20—155A 4.7B-parameter Mixture-of-Experts genomic foundation model pretrained on ~1.2 trillion nucleotide tokens from human-associated microbial genomes.
DNA & Gene73OpennessAlbatross
———An RNA language model trained by self-supervised masked-nucleotide prediction on ~50,000 IRES sequences that predicts secondary-structure features rivaling experimental chemical probing.
RNA15OpennessA self-supervised metabolomic foundation model pretrained on NMR metabolite profiles from 430,000+ UK Biobank participants, applied without backbone retraining to aging, subtyping, and risk tasks.
Metabolomics7OpennessTMEformer
———A spatial-transcriptomics foundation model for the tumor microenvironment that produces TME-aware embeddings and enables in silico perturbation from a fixed pretrained checkpoint.
Spatial omics10OpennessSE(3)-invariant masked autoencoder pretrained on ~370K AlphaFold-DB structures for protein fold representation learning, enabling frozen-feature and zero-shot fold classification.
Protein78OpennessPLM-SAE
———A mechanistic-interpretability framework that trains sparse autoencoders on protein language model embeddings to extract interpretable features for zero-shot variant effect prediction.
Protein22OpennessENSEMBITS
7——A residual VQ-VAE tokenizer that learns a discrete alphabet of protein conformational ensembles from molecular dynamics data, usable as a frozen representation layer for downstream tasks.
Protein66OpennessMuseDrift
———An 85M-parameter conditional discrete diffusion model for protein variant generation with a calibrated identity dial to steer similarity to a wild-type sequence.
Protein12Openness