All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 316 filtered models
LEAF-1
———Genomics foundation model that represents individual DNA fragments in a learned semantic space for cell-free DNA cancer detection and cell typing.
DNA & GeneSingle-cell4OpennessWattmaMod
———RNA modification profiling from nanopore direct RNA-seq signal; self-supervised pretraining resolves 11 modification types and extends to new ones.
RNABiosignals21OpennessSelf-supervised 3D masked autoencoder for volumetric fluorescence microscopy, aligned to ESM2 embeddings to predict protein localization.
ImagingSingle-cell71OpennessEventHorizon
———ARUP Laboratories +1 otherJune 22, 2026cell_type_annotationdiagnostic_classificationflow_cytometry+6Self-supervised foundation model for clinical flow cytometry, producing panel-agnostic specimen-level representations from multi-panel data.
BiosignalsSingle-cell4OpennessUltraNMR
11—Hong Kong University of Science and Technology +4 othersJune 18, 2026foundation_modelself_supervisedtransfer_learning+1NMR foundation model trained on 158 million simulated 1H and 13C spectra, transferring simulation-learned representations to real experimental data.
Small moleculeMetabolomics43OpennessTox21mer
———National Institute of Environmental Health SciencesJune 15, 2026embeddingsfoundation_modelrepresentation_learning+2Toxicity screening foundation model that encodes Tox21 concentration-response curves and assay metadata into reusable 768-dimensional embeddings.
Small moleculeBiosignals23OpennessRepGene
———Gene representation framework fusing DNA, transcript, protein, text, and single-cell embeddings into one latent space that survives missing views.
DNA & GeneProteinSingle-cell22OpennessDNAGPT2
———Family of ten compact GPT-2 decoder-only DNA language models spanning BPE vocabularies from 16 to 8192 tokens, built for lossless genome compression.
DNA & Gene52OpennessHoloCell
———860M-parameter generative single-cell foundation model that jointly represents and generates epigenomic, transcriptomic, and proteomic modalities.
Single-cellDNA & Gene21OpennessTifBERT
2——Bulk RNA-seq foundation model learning normalization-robust transcriptome representations via TF-IDF gene ordering and masked gene modeling.
RNA17OpennessMethylSeqNet
———University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6Gene regulation model that conditions a pretrained DNA sequence embedding on CpG methylation to capture cell-type and allele-specific regulation.
DNA & Gene18OpennessSpineAgent
6——Multi-sequence spine MRI foundation model with DINOv3 encoders, supporting condition classification, pathology localization, and report generation.
Imaging55OpennessDaX
2——Pathology vision foundation model adapting DINOv3 self-supervised learning to whole-slide histopathology across many magnifications and scales.
Pathology11OpennessLDARNet
41—Genomic foundation model with 120M parameters that learns adaptive DNA token boundaries by dynamic chunking, not fixed k-mer or byte-pair tokens.
DNA & Gene26OpennessSQUALL
———Multimodal foundation model pretrained on 1.76B histology and spatial transcriptomics spots, inferring molecular state from whole-slide images.
PathologySpatial omics6OpennessBrainGFM
173—Graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero-shot disorder classification.
Biosignals16OpennessPepForge
4——Generative model for chemically modified and macrocyclic peptides that builds molecules in HELM notation, supporting de novo design and infilling.
ProteinSmall molecule94OpennessCryoProt
———Protein representation learning from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.
ImagingProtein11OpennessTESSERA
5——Self-supervised foundation model that embeds cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types for tumor subtyping.
DNA & Gene28OpennessTxFM
2——Transcriptomics foundation model from Recursion that masks and reconstructs RNA-seq gene expression counts to learn reusable sample embeddings.
Single-cell12OpennessGlucoFM
—2—Google Research +1 otherMay 29, 2026continuous_glucose_monitoringfoundation_modelglucose_forecasting+4Self-supervised foundation model for continuous glucose monitoring, with dual streams separating slow physiological state from transient events.
Biosignals11Openness