All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 257 filtered models

  • MethylSeqNet

    University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6

    Conditions a pretrained DNA sequence embedding on CpG methylation to predict gene regulation across cell types and alleles, generalizing zero-shot to imprinting, X-inactivation, and accessibility.

    DNA & Gene
    18Openness
  • DaX

    1
    DAMO AcademyJune 5, 2026biomarker_predictioncancer_subtypingdino+5

    Pathology vision foundation model adapting DINOv3-style self-supervised learning to whole-slide histopathology across continuous magnifications and scales.

    Pathology
    11Openness
  • LDARNet

    1
    Independent ResearcherJune 3, 2026dnafoundation_modelgene_expression+6

    A 120M-parameter genomic foundation model that learns adaptive DNA token boundaries via H-Net-style dynamic chunking instead of fixed k-mer or byte-pair tokenization.

    DNA & Gene
    26Openness
  • SQUALL

    Peking UniversityJune 3, 2026biomarker_discoveryfoundation_modelgene_expression+6

    Multimodal foundation model pretrained on 1.76 billion paired histology-spatial transcriptomics spots, linking whole-slide images to spatial molecular programs.

    PathologySpatial omics
    6Openness
  • BrainGFM

    173
    Lehigh University +1 otherJune 2, 2026brain_connectomedisorder_classificationfmri+7

    A graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero/few-shot generalization to unseen disorders.

    Biosignals
    16Openness
  • PepForge

    4
    Technical University of BerlinJune 2, 2026antimicrobial_peptidesbertde_novo_design+7

    A hierarchical three-stage cascade that generates chemically modified and macrocyclic peptides in HELM notation, supporting de novo design and constrained infilling.

    ProteinSmall molecule
    94Openness
  • CryoProt

    Hunan University +1 otherJune 1, 2026active_site_identificationbinding_affinitycryo_em+7

    Protein pretraining framework that learns representations directly from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.

    ImagingProtein
    11Openness
  • TESSERA

    5
    Weill Cornell MedicineJune 1, 2026cancer_genomicscell_type_annotationcontrastive_learning+6

    Self-supervised foundation model that learns reusable representations of cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types.

    DNA & Gene
    28Openness
  • TxFM

    2
    Recursion PharmaceuticalsMay 31, 2026autoencoderfoundation_modelgene_expression+4

    A self-supervised masked autoencoder for RNA-seq count data, pretrained on 1.4M public samples to learn transferable transcriptomic representations without per-dataset re-training.

    Single-cell
    12Openness
  • GlucoFM

    Google Research +1 otherMay 29, 2026continuous_glucose_monitoringfoundation_modelglucose_forecasting+4

    A dual-stream self-supervised foundation model for continuous glucose monitoring data, separating slow physiological state from transient glucose events.

    Biosignals
    11Openness
  • Chreode

    University of North Carolina at Chapel Hill +2 othersMay 27, 2026cell_fate_predictioncrispr_perturbationdevelopmental_trajectory_modeling+8

    A cell world model pretrained on a 2.4M-cell mouse embryonic atlas that predicts one-step transcriptional state transitions and transfers to perturbation prediction.

    Single-cell
    26Openness
  • GEARS

    University of Central Florida +2 othersMay 27, 2026cell_localizationdiffusion_modeldomain_adaptation+8

    Geometry-first generative framework that reconstructs single-cell spatial coordinates by integrating scRNA-seq with spatial transcriptomics, without cell-type labels.

    Single-cell
    22Openness
  • OryzaG3

    Hainan UniversityMay 26, 2026causal_language_modeldnagenomic_variant_prediction+8

    A 700M-parameter DNA language model pretrained on the rice pangenome, built as a reusable foundation model for crop genomics and molecular breeding.

    DNA & Gene
    19Openness
  • Hong Kong University of Science and Technology +9 othersMay 25, 2026clinical_decision_supportfoundation_modellung_tissue+7

    A subspecialty lung-pathology foundation model, fine-tuned from Virchow2 and prospectively validated across 32 clinical tasks spanning the lung diagnostic workflow.

    Pathology
    5Openness
  • C3P

    University of TorontoMay 24, 2026bacterial_genomeco_regulated_gene_retrievalcontrastive_learning+8

    Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.

    DNA & Gene
    77Openness
  • D2D

    Vrije Universiteit Brussel +1 otherMay 22, 2026binding_region_predictionepistasisintrinsically_disordered_regions+5

    Combines the ProtT5-XL protein language model with protein-specific evolutionary constraints to predict mutational effects on stability, binding, and epistasis—largely zero-shot.

    Protein
    29Openness
  • Genos-m

    20155
    BGI-HangzhouAIMay 21, 2026foundation_modelgene_fitness_predictionmetagenomics+7

    A 4.7B-parameter Mixture-of-Experts genomic foundation model pretrained on ~1.2 trillion nucleotide tokens from human-associated microbial genomes.

    DNA & Gene
    73Openness
  • Albatross

    Harvard Medical SchoolMay 20, 2026ireslanguage_modelsecondary_structure_prediction+4

    An RNA language model trained by self-supervised masked-nucleotide prediction on ~50,000 IRES sequences that predicts secondary-structure features rivaling experimental chemical probing.

    RNA
    15Openness
  • MetFoundation

    Hong Kong Baptist UniversityMay 20, 2026aging_clockcontrastive_learningdisease_risk_prediction+6

    A self-supervised metabolomic foundation model pretrained on NMR metabolite profiles from 430,000+ UK Biobank participants, applied without backbone retraining to aging, subtyping, and risk tasks.

    Metabolomics
    7Openness
  • TMEformer

    Sichuan UniversityMay 20, 2026cancerfoundation_modelin_silico_perturbation+8

    A spatial-transcriptomics foundation model for the tumor microenvironment that produces TME-aware embeddings and enables in silico perturbation from a fixed pretrained checkpoint.

    Spatial omics
    10Openness
  • ETH ZurichMay 18, 2026autoencoderfold_classificationfoundation_model+5

    SE(3)-invariant masked autoencoder pretrained on ~370K AlphaFold-DB structures for protein fold representation learning, enabling frozen-feature and zero-shot fold classification.

    Protein
    78Openness
  • PLM-SAE

    Shanghai Smart Logic Technology Co., Ltd.May 15, 2026autoencoderproteomicsrepresentation_learning+3

    A mechanistic-interpretability framework that trains sparse autoencoders on protein language model embeddings to extract interpretable features for zero-shot variant effect prediction.

    Protein
    22Openness
  • ENSEMBITS

    7
    Vanderbilt UniversityMay 13, 2026function_predictionmolecular_dynamicsprotein_dynamics+5

    A residual VQ-VAE tokenizer that learns a discrete alphabet of protein conformational ensembles from molecular dynamics data, usable as a frozen representation layer for downstream tasks.

    Protein
    66Openness
  • MuseDrift

    University of Florida +1 otherMay 12, 2026de_novo_designdiffusiongenerative+3

    An 85M-parameter conditional discrete diffusion model for protein variant generation with a calibrated identity dial to steer similarity to a wild-type sequence.

    Protein
    12Openness
...