All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 49–72 of 217 filtered models
Carbon
200—6.4KAutoregressive DNA foundation model for variant effect prediction, using 6-mer tokenization to match Evo2-7B win rates at far higher throughput.
DNA & Gene93OpennessCoMole
———Motif-aware graph diffusion model for controllable molecular generation that adapts to unseen properties by learning a lightweight task embedding.
Small molecule23OpennessPhoenix
———Virtual spatial transcriptomics foundation model predicting pan-cancer, spatially-resolved single-cell gene expression from H&E histology slides.
PathologySpatial omics8OpennessMIMIC
37——Generative multimodal foundation model spanning DNA, RNA, and protein, with any-to-any inference across genome, transcriptome, and proteome.
RNAProteinDNA & Gene16OpennessGenNA
———Autoregressive nucleotide-and-text foundation model generating DNA and RNA sequences from natural-language prompts that name species and function.
DNA & GeneRNA16OpennessAF2Dock
151—Protein-protein docking model adapting AlphaFold-Multimer with a docking module and flow-matching training to assemble subunits without MSAs.
Protein77Openness110M-parameter RNA language model that designs sequences from secondary structure, motif, and Gene Ontology constraints via discrete diffusion.
RNA48OpennessMMPT-FM
3——Chemical language model that generates matched molecular pair transformations from SMILES and SMARTS to design medicinal-chemistry analogs.
Small moleculeLanguage model82OpennessRNA inverse folding framework pairing a graph neural network predictor with a diffusion model, designing sequences from self-contained RNA units.
RNA17OpennessSMILE
———Schrödinger-bridge diffusion model for virtual multiplex staining, translating routine H&E histology into multiplex immunohistochemistry images.
Pathology8OpennessEncoder-decoder Transformer that generates intrinsically disordered protein sequences conditioned on target conformational-ensemble descriptors.
Protein10OpennessLinkLlama
10115Molecular linker design model fine-tuned from Llama 3 that emits PROTAC and fragment linkers as SMILES from natural-language geometry prompts.
Small molecule27OpennessGerminal
27234—Generative pipeline for epitope-targeted de novo antibody (nanobody) CDR design that yields nanomolar binders from only dozens of designs per antigen.
Protein37OpennessxVERSE
———Transcriptomics-native single-cell foundation model that learns batch-invariant cell representations and probabilistically generates virtual cells.
Single-cell10OpennessProtenix-v2
2K7—464M-parameter structure prediction and design model that improves antibody-antigen complex accuracy over Protenix-v1 and adds generative VHH design.
Protein81OpennessDISCO
2103—Multimodal diffusion model that co-designs protein sequence and 3D structure around cofactors and small molecules for de novo heme enzyme design.
Protein70OpennessMuPD
———Diffusion-transformer pathology model embedding H&E histology, RNA profiles, and clinical text in a latent space for zero-shot cross-modal synthesis.
PathologySpatial omics15OpennessDiscrete diffusion model that designs regulatory DNA with tunable cell-type-specific activity and learns activity-predictive representations.
DNA & Gene49OpennessProtiCelli
241—Generative imaging model simulating single-cell fluorescence microscopy for all 12,800 human proteins in the Human Protein Atlas.
Imaging51OpennessEnzyGen2
30——Protein foundation model for de novo enzyme design that co-designs sequence and 3D structure under small-molecule ligand guidance, at 730M parameters.
ProteinSmall molecule89OpennessCLOP-DiT
———Generates single-cell transcriptomes from structured biological metadata via contrastive language-omics pretraining and a diffusion transformer.
Single-cell10OpennessLingshu-Cell
—3—Virtual cell model using masked discrete diffusion over the whole transcriptome to simulate scRNA-seq perturbation responses across tissues.
Single-cell21OpennessIDPForge
162—Chinese Academy of SciencesMarch 25, 2026conformational_ensembleconformational_ensemble_generationdiffusion+7Protein-language diffusion model generating all-atom conformational ensembles for intrinsically disordered proteins and disordered regions.
Protein29OpennessProAR
———Autoregressive generative model for protein molecular dynamics that emits flexible-length trajectories frame by frame with anti-drifting sampling.
Protein19Openness