Every biological foundation model, evaluated and ranked by the bio.rodeo team
Histopathology model predicting TP53 mutation status, TP53 RNA expression, and tumour taxonomy from H&E whole-slide images across 32 solid cancers.
Self-supervised Siamese network for cryo-electron tomography, enabling zero-shot denoising, segmentation, and macromolecule detection in tomograms.
Spectral prediction model for modified peptides, forecasting fragment-ion intensities and retention time with zero-shot generalization to unseen PTMs.
Multimodal conversational LLM for metabolite analysis, fusing a molecular-graph GNN and molecular-image CNN with a Vicuna-13B language backbone.
Denoising diffusion bridge model for peptide binder design that generates ligand surfaces and backbones complementary to a target receptor surface.
Protein dynamics model that samples conformational ensembles autoregressively at slow and fast timescales, generalizing zero-shot to unseen proteins.
Equivariant diffusion model that converts peptide binders into drug-like small molecules, generating peptidomimetics inside the target protein pocket.
Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.
Multi-target drug discovery framework pairing a diffusion-transformer generator with evolutionary latent-space search and synthesis-aware scoring.
Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.
Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.
Single-cell latent diffusion model fine-tuned on 14.5 million CD4+ T cells to simulate transcriptomic effects of single-gene perturbations.
Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.
Hierarchical transformer with 1.2 billion parameters that predicts personalized gene expression from diploid genomes for variant effect prediction.
Histopathology foundation model extracting general-purpose features from H&E patches by distilling the UNI, Phikon, and CONCH pathology encoders.
Antibody language model adapted on paired heavy and light chains, using CDR-focused masking to sharpen embeddings for binding affinity prediction.
Structure-based drug design model that generates ligands for a protein pocket, pairing a diffusion structure encoder with preference optimization.
Structure-based conformational B-cell epitope predictor that scores local antigen surface patches with ESM-2 embeddings and an ensemble MLP.
Foundation model for tandem mass spectrometry that embeds MS/MS spectra into a learned chemical space, resolving isomers and classifying disease.
Enzyme backbone design model that adds substrate and catalytic-site control to a pretrained SE(3) flow-matching generator via a lightweight adapter.