All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–48 of 158 filtered models
PIGMENT
———Physics-informed generative foundation model for quantitative diffusion MRI that maps brain microstructure and adapts zero-shot to each participant.
Imaging11OpennessSTMDiT
———Diffusion transformer for virtual tissue synthesis, generating H&E histopathology patches conditioned on spatial gene expression and morphology.
PathologySpatial omics44OpennessGenBloom
3——Genetically aligned foundation model for blood smear cytology that links single-cell morphology to the chromosomal aberrations behind AML and APL.
Pathology65OpennessLucaPhylo
13——Hyperbolic protein language model for alignment-free phylogenetic inference, turning ESM2-650M embeddings into distance matrices for tree placement.
Protein86OpennessD2D
1——Vrije Universiteit Brussel +1 otherMay 22, 2026binding_region_predictionepistasisintrinsically_disordered_regions+5Variant effect predictor pairing a protein language model with family-specific evolutionary constraints to score stability, binding, and epistasis.
Protein29OpennessGenos-m
26—123Mixture-of-Experts genomic foundation model for the human microbiome, with 4.7B parameters pretrained on bacterial, archaeal, and phage genomes.
DNA & Gene73OpennessProtmRNA
2——Codon-level mRNA language model adapted from ESM-2 650M by swapping amino-acid tokens for codon tokens, transferring protein knowledge to mRNA tasks.
RNA11OpennessTMEformer
———Spatial transcriptomics foundation model for the tumor microenvironment, giving TME-aware embeddings and in silico perturbation from one checkpoint.
Spatial omics10OpennessDamageFormer
1——Multimodal framework that detects and localizes DNA lesions from native nanopore signal, built on the damage-aware LesionBERT foundation model.
DNA & Gene45OpennessBio-BLIP
———Multimodal Q-former that fuses DNA sequence, gene context, protein function, and text for zero-shot variant interpretation with a frozen LLM.
DNA & GeneLanguage model23OpennessPLM-SAE
———Sparse autoencoders trained on protein language model embeddings to expose interpretable features and drive zero-shot variant effect prediction.
Protein22OpennessDomain-specific foundation model for zero-shot plant root image segmentation, built on a MobileSAM backbone and trained across nine root datasets.
Imaging74OpennessENSEMBITS
7——Protein conformational ensemble tokenizer that learns a discrete alphabet of states from molecular dynamics, reusable as a frozen feature layer.
Protein66OpennessFLASH
———Signed heterogeneous graph foundation model over the SIGMA-KG knowledge graph, predicting drug mode of action and drug-drug interactions zero-shot.
Small molecule10OpennessSusagi
8—4Microbiome world model that treats a community as a set of taxa, scoring how well each member fits and predicting community dynamics zero-shot.
DNA & Gene48OpennessBRIDGE
———The University of Hong KongMay 8, 2026contrastive_learningfoundation_modelgene_expression_prediction+8Multi-organ foundation model aligning histology images with spatial-transcriptomics profiles for zero-shot expression and survival prediction.
PathologySpatial omics31OpennessWaypoint
———Microbiome foundation models that treat microbial community composition as a language, enabling zero- and few-shot transfer across prediction tasks.
DNA & Gene23Openness- University of KentuckyMay 4, 2026contrastive_learningintrinsic_disorder_predictionmolecular_dynamics+6
Protein language model aligning ESM sequence embeddings with molecular dynamics trajectories for zero-shot mutation effect and stability prediction.
Protein10Openness RNABag
———HomiGen Intelligence Technology Co., Ltd.April 22, 2026cancer_detectioncell_type_annotationfoundation_model+6Transcriptome foundation model for precision oncology, generalizing zero-shot across tissue, plasma cfRNA, and tumor-educated platelet modalities.
Single-cell46OpennessOneGenome-Rice
25—15Genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window and a 1.25B-parameter mixture-of-experts transformer.
DNA & Gene90OpennessDIA-CLIP
———AI for Science Institute +1 otherApril 16, 2026contrastive_learningencoder_decoderfoundation_model+6Contrastive dual-encoder model for DIA proteomics, embedding peptides and spectra in a shared space for zero-shot peptide-spectrum matching.
Protein11OpennessMuPD
———Diffusion-transformer pathology model embedding H&E histology, RNA profiles, and clinical text in a latent space for zero-shot cross-modal synthesis.
PathologySpatial omics15OpennessPlantCAD2
97—4.2KLong-context plant DNA language model, 676M parameters on a Mamba2 backbone, pretrained on 65 angiosperm genomes for cross-species variant annotation.
DNA & Gene69OpennessAINN-P1
———Compact 167M-parameter protein language model built on a multiplicative LSTM, giving zero-shot variant effect and fitness prediction from sequence.
Protein12Openness