All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 158 filtered models

  • LEAF-1

    McGill University +1 otherJuly 10, 2026cancer_detectioncell_type_annotationcfdna+5

    Genomics foundation model that represents individual DNA fragments in a learned semantic space for cell-free DNA cancer detection and cell typing.

    DNA & GeneSingle-cell
    4Openness
  • TRIOPS

    UC Santa CruzJuly 4, 2026cnncross_attentionimmune_repertoire_analysis+4

    T-cell receptor-MHC restriction prediction from amino acid sequence, mapping TCRs to their restricting HLA allele at 0.97 held-out AUC.

    Protein
    22Openness
  • GAZE

    Leiden University Medical CenterJuly 2, 2026enzymesfoundation_modelgraph_neural_network+2

    Physics-informed graph neural network predicting metabolite concentrations from gene expression, generalizing zero-shot to unseen metabolites.

    MetabolomicsSmall moleculeDNA & Gene
    19Openness
  • AstraZenecaJune 29, 2026contrastive_learninggene_expressionhistology+2

    Histopathology-to-molecular alignment model that queries H&E slides with gene-set signatures to predict pathway activity without sequencing.

    PathologyRNA
    16Openness
  • PlantGeneAnn

    12126
    Huazhong Agricultural UniversityJune 25, 2026dnafoundation_modelgene_structure_annotation+7

    Plant genome foundation model for ab initio gene structure annotation, predicting genes, coding sequences, and exons at single-nucleotide resolution.

    DNA & Gene
    66Openness
  • Navigo

    12
    Chinese University of Hong Kong +1 otherJune 24, 2026cell_fate_engineeringflow_matchinggene_regulatory_network_inference+6

    Generative framework that learns a developmental vector field from scRNA-seq snapshots, coupling flow matching with molecular RNA kinetics.

    Single-cellRNA
    44Openness
  • JEDEL

    University of Southampton +1 otherJune 21, 2026de_novo_designdna_encoded_librariesdrug_discovery+6

    Zero-shot generative framework that turns 3D pharmacophores into synthesis-ready DNA-encoded libraries of purchasable building blocks.

    Small molecule
    23Openness
  • GENATATOR

    23
    AIRI InstituteJune 17, 2026gene_annotationgene_structure_predictiontransfer_learning+2

    Ab initio gene annotation model that predicts gene boundaries and exon-intron structure from raw DNA, generalizing zero-shot to unseen species.

    DNA & GeneRNA
    22Openness
  • Omnii

    Radical NumericsJune 15, 2026convolutionaldnafoundation_model+6

    Genomic language model from Radical Numerics with a 2 Mbp context window, built for zero-shot variant effect prediction and sequence design.

    DNA & Gene
    5Openness
  • TifBERT

    2
    York UniversityJune 11, 2026bertfoundation_modelgene_expression+5

    Bulk RNA-seq foundation model learning normalization-robust transcriptome representations via TF-IDF gene ordering and masked gene modeling.

    RNA
    17Openness
  • MethylSeqNet

    University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6

    Gene regulation model that conditions a pretrained DNA sequence embedding on CpG methylation to capture cell-type and allele-specific regulation.

    DNA & Gene
    18Openness
  • VelocityFM

    University of Colombo School of Computing +1 otherJune 7, 2026conformational_samplingflow_matchinggenerative+4

    Generative protein-dynamics model that predicts short molecular dynamics trajectories with rectified flow matching over residue frames and torsions.

    Protein
    21Openness
  • Cellpin

    Technical University of MunichJune 5, 2026denoisinggene_imputationsingle_cell+4

    Variational autoencoder trained on scRNA-seq and applied frozen to impute unmeasured genes and denoise spatial transcriptomics profiles.

    Spatial omicsSingle-cell
    22Openness
  • tf-SFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+5

    Transcription factor-DNA binding specificity prediction from sequence, with a physics-derived dual-encoder trained by symmetric contrastive learning.

    DNA & Gene
    18Openness
  • drug-SFM

    1
    ETH ZurichJune 4, 2026contrastive_learningcross_modal_retrievaldrug_repurposing+8

    Specificity foundation model predicting small-molecule drug-target binding from sequence, scored as cross-modal retrieval without docking or assays.

    Small molecule
    16Openness
  • ReCLIP

    University of Chicago +2 othersJune 4, 2026multi_taskprotein_protein_interaction_predictionproteomics+4

    Transformer that predicts protein-protein interactions at residue resolution, spanning mutations, PTMs, peptide-MHC binding, and disease variants.

    Protein
    22Openness
  • crisprSFM

    2
    ETH ZurichJune 4, 2026contrastive_learningcrisprcross_modal_retrieval+6

    CRISPR off-target prediction model that scores gRNA-DNA specificity from sequence, framing guide-target recognition as cross-modal retrieval.

    DNA & Gene
    19Openness
  • enzyme-SFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Enzyme-substrate specificity model that scores catalytic pairs from sequence with a physics-derived dual-encoder and a contrastive objective.

    Protein
    23Openness
  • mhcSFM

    2
    ETH ZurichJune 4, 2026binding_predictioncontrastive_learningcross_modal_retrieval+6

    Peptide-MHC binding specificity model that frames presentation as cross-modal retrieval, aligning peptide and MHC encoders by contrastive learning.

    Protein
    23Openness
  • mir-SFM

    2
    ETH ZurichJune 4, 2026contrastive_learningcross_modal_retrievaldual_encoder+6

    Foundation model that predicts microRNA-mRNA target specificity from sequence, using a dual-encoder trained with a symmetric contrastive objective.

    RNA
    25Openness
  • BrainGFM

    173
    Lehigh University +1 otherJune 2, 2026brain_connectomedisorder_classificationfmri+7

    Graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero-shot disorder classification.

    Biosignals
    16Openness
  • Vermeer

    3
    Microsoft Research +2 othersJune 1, 2026autoregressivecell_biologyfluorescence_microscopy+7

    Generative microscopy foundation model that synthesizes in-silico fluorescence images of protein subcellular localization from amino-acid sequence.

    ImagingProtein
    17Openness
  • AMix-2

    Shanghai AI Laboratory +4 othersMay 30, 2026diffusionfold_classificationfoundation_model+6

    Protein-text foundation model placing amino acid sequences and natural language in one token space for protein understanding and de novo design.

    ProteinLanguage model
    10Openness
  • Nanjing University +2 othersMay 30, 2026foundation_modelgene_expression_predictionhistology+5

    Tri-modal foundation model unifying histology images, spatial transcriptomics, and language for zero-shot pathology and spatial biology reasoning.

    PathologySpatial omics
    65Openness