All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 2548 of 125 filtered models

  • SpeciefAI

    University of EdinburghMarch 16, 2026antibodyantibody_designgenerative+5

    Transformer that generates multi-species antibody and nanobody framework regions at the mRNA level, conditioned on input CDRs, across six species.

    ProteinRNA
    46Openness
  • National University of SingaporeMarch 10, 2026antibodybinding_affinity_predictionfoundation_model+6

    Paired-sequence protein language model that jointly encodes two interacting chains to predict interactions, binding affinity, and interface contacts.

    Protein
    27Openness
  • HitAnno

    Tsinghua UniversityMarch 10, 2026cell_type_annotationchromatin_accessibilitylanguage_model+4

    Hierarchical language model for atlas-level cell-type annotation of scATAC-seq data that annotates new query datasets without retraining.

    Single-cell
    14Openness
  • CALM-1.0

    3
    ETH ZurichFebruary 26, 2026antibodyantibody_designantigen+6

    Contrastive antibody language model predicting antibody-antigen binding specificity from sequence with a dual-encoder, cross-attentive architecture.

    Protein
    10Openness
  • OncoBERT

    National Cancer InstituteFebruary 19, 2026bertlanguage_modeloncology+7

    BERT-style language model for somatic mutations, pretrained on cancer sequencing from 210,000+ patients for tumor subtyping and therapy response.

    DNA & Gene
    7Openness
  • resLens

    3
    George Washington UniversityFebruary 16, 2026genomicslanguage_modelmetagenomics+3

    Genomic language models fine-tuned to detect and classify antibiotic resistance genes, catching divergent ARGs that reference alignment misses.

    DNA & Gene
    11Openness
  • AntigenLM

    Chinese Academy of Sciences +1 otherFebruary 9, 2026dnafoundation_modelgenerative+5

    Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.

    DNA & Gene
    5Openness
  • ARSENAL

    16
    Stanford UniversityFebruary 6, 2026chromatinlanguage_modelmotif_discovery+6

    Masked DNA language model for regulatory genomics with a motif-discovery regularizer for zero-shot TF motif recovery and variant effect prediction.

    DNA & Gene
    29Openness
  • BioBridge

    2
    Tongji University +1 otherFebruary 4, 2026continual_learninglanguage_modelmultimodal+5

    Connects a frozen protein language model to a general LLM via a cross-modal projector, adding protein reasoning without catastrophic forgetting.

    Language modelProtein
    13Openness
  • NUWA

    Kitasato UniversityFebruary 4, 2026bertfoundation_modellanguage_model+5

    mRNA language foundation model trained on ~115M protein-coding sequences across the tree of life, unifying mRNA perception and generation.

    RNADNA & Gene
    16Openness
  • Proust

    9
    ETH ZurichFebruary 2, 2026foundation_modellanguage_modelprotein_design+3

    Causal 309M-parameter protein language model that scores variant fitness zero-shot and generates sequences, reaching 0.390 Spearman on ProteinGym.

    Protein
    9Openness
  • Helmholtz Munich +2 othersJanuary 22, 2026language_modelmolecular_dynamicsproteomics+5

    LoRA adapter on ProstT5 predicting per-residue distributions over Foldseek 3Di tokens, capturing conformational flexibility from MD trajectories.

    Protein
    93Openness
  • Seoul National University HospitalJanuary 12, 2026cancercell_type_annotationdata_generation+6

    Single-cell RNA-seq language model that treats cells as gene-expression tokens, synthesizing whole transcriptomes from tissue and disease metadata.

    Single-cellSpatial omics
    2Openness
  • CMAP

    Amazon Web ServicesJanuary 7, 2026antibodyantibody_developabilityin_context_learning+4

    Antibody developability predictor pairing text and protein language models, using in-context learning to fit new assays without retraining.

    ProteinLanguage model
    4Openness
  • DNAChunker

    1
    KAIST +1 otherJanuary 6, 2026dnafunctional_genomicsgenomics+4

    Masked DNA language model with a learnable, adaptive tokenizer that produces context-dependent, variable-length segments instead of fixed k-mers.

    DNA & Gene
    23Openness
  • BiomeGPT

    1
    Massachusetts General HospitalJanuary 5, 2026biomarker_discoverydisease_classificationfoundation_model+6

    Gut microbiome foundation model pretrained on human shotgun metagenomes, learning species-level taxonomic representations for disease prediction.

    DNA & GeneLanguage model
    8Openness
  • GEMGen

    2
    Westlake University +1 otherJanuary 3, 2026de_novo_designdrug_discoverygenerative+5

    Generative language model for phenotype-driven drug discovery, proposing small-molecule structures from up- and down-regulated gene signatures.

    Small moleculeSingle-cell
    9Openness
  • HELM-BERT

    14471
    Kyoto UniversityDecember 29, 2025debertalanguage_modelmacrocycles+7

    Peptide language model trained on HELM notation, a DeBERTa encoder for property prediction on macrocyclic and non-canonical medium-sized peptides.

    Small molecule
    80Openness
  • Kitasato University +2 othersDecember 24, 2025codoncodon_optimizationfoundation_model+7

    GPT-style generative language model for mRNA coding sequences, pretrained across bacteria, eukaryotes, and archaea for de novo CDS design.

    RNA
    39Openness
  • ProFam

    582
    University College London +1 otherDecember 21, 2025de_novo_designgenerativelanguage_model+5

    Protein-family language model trained on unaligned homolog sets for zero-shot variant fitness prediction and design. ProFam-1 holds 251M parameters.

    Protein
    86Openness
  • HD-Prot

    74
    The Hong Kong Polytechnic University +2 othersDecember 17, 2025diffusiongenerativeinverse_folding+6

    Multimodal protein language model that adds a continuous-token diffusion head to a discrete pLM, modeling structure without vector quantization.

    Protein
    14Openness
  • vir2vec

    31388
    University of FloridaDecember 12, 2025embeddingsfoundation_modelgenomics+6

    Pan-viral genomic language model producing fixed genome-level embeddings of viral DNA and RNA, reused across classification tasks without retraining.

    DNA & Gene
    53Openness
  • scMOBA

    Chinese Academy of Sciences +1 otherDecember 2, 2025cell_biologycell_type_annotationdata_integration+5

    Conversational single-cell and spatial multi-omics brain foundation model, with zero-shot cell annotation and disease prediction across species.

    Single-cellLanguage model
    5Openness
  • Tongji University +1 otherNovember 28, 2025cell_type_annotationfoundation_modelgene_expression+6

    Single-cell foundation model adapting LLaMA-3.1-8B with LoRA, recasting transcriptomes and protein interaction networks as natural-language Q&A pairs.

    Single-cellRNA
    55Openness