All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 125 filtered models

  • TEDlm

    University College LondonJuly 13, 2026language_modelprotein_function_predictiontransformer

    Protein language model pretrained on structural domain segments, encoding fold and contact signals for remote-homology detection from sequence alone.

    Protein
    20Openness
  • DrugGen 2

    6834
    Isfahan University of Medical SciencesJuly 9, 2026de_novo_designdrug_discoverylanguage_model+4

    Generative language model that designs drug-like SMILES conditioned on disease ontology and a target protein sequence for de novo drug discovery.

    Small moleculeProtein
    51Openness
  • ProLoc

    Nanjing UniversityJune 27, 2026functional_region_localizationlanguage_modelmultimodal+3

    Text-guided localization model that grounds natural-language functional descriptions to specific residue regions of a protein sequence.

    ProteinLanguage model
    10Openness
  • Washington University in St. LouisJune 22, 2026cell_biologycell_type_annotationgene_expression+5

    Single-cell language model that prepends biomedical knowledge-graph tokens to cell sentences, grounding cell type annotation in pathway structure.

    Single-cellLanguage model
    23Openness
  • BioMatrix

    41167
    Shanghai AI Laboratory +1 otherJune 20, 2026foundation_modellanguage_modelmolecule_generation+6

    Decoder-only foundation model that unifies sequences, 3D structures, and natural language for small molecules and proteins in one shared token space.

    ProteinSmall moleculeLanguage model
    67Openness
  • DNAGPT2

    CEITEC Masaryk UniversityJune 12, 2026dnadna_language_modelinggenomics+5

    Family of ten compact GPT-2 decoder-only DNA language models spanning BPE vocabularies from 16 to 8192 tokens, built for lossless genome compression.

    DNA & Gene
    52Openness
  • GermRL

    14
    Johns Hopkins UniversityJune 11, 2026antibodyantibody_designde_novo_design+6

    Reinforcement learning framework that fine-tunes the ProGen2-OAS antibody language model with GRPO to cut germline bias in generated sequences.

    Protein
    65Openness
  • BacteReason

    University of TokyoJune 7, 2026antimicrobial_resistanceantimicrobial_resistance_predictionbacteria+5

    Reasoning LLM that predicts antimicrobial susceptibility of clinical bacterial isolates and supplies mechanistic explanations for each prediction.

    DNA & GeneLanguage model
    20Openness
  • AMix-2

    Shanghai AI Laboratory +4 othersMay 30, 2026diffusionfold_classificationfoundation_model+6

    Protein-text foundation model placing amino acid sequences and natural language in one token space for protein understanding and de novo design.

    ProteinLanguage model
    10Openness
  • LucaPhylo

    13
    Alibaba Cloud +2 othersMay 26, 2026few_shotlanguage_modelphylogenetic_inference+5

    Hyperbolic protein language model for alignment-free phylogenetic inference, turning ESM2-650M embeddings into distance matrices for tree placement.

    Protein
    86Openness
  • OryzaG3

    Hainan UniversityMay 26, 2026causal_language_modeldnagenomic_variant_prediction+8

    700M-parameter DNA language model pretrained on the rice pangenome, serving as a reusable base model for crop genomics and molecular breeding.

    DNA & Gene
    19Openness
  • C3P

    1
    University of TorontoMay 24, 2026bacterial_genomeco_regulated_gene_retrievalcontrastive_learning+8

    Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.

    DNA & Gene
    77Openness
  • ProtmRNA

    2
    Fudan University +2 othersMay 20, 2026codongene_expressionlanguage_model+7

    Codon-level mRNA language model adapted from ESM-2 650M by swapping amino-acid tokens for codon tokens, transferring protein knowledge to mRNA tasks.

    RNA
    11Openness
  • Albatross

    Harvard Medical SchoolMay 20, 2026ireslanguage_modelsecondary_structure_prediction+4

    RNA language model that predicts secondary structure of internal ribosome entry sites from sequence alone, trained on roughly 50,000 IRES sequences.

    RNA
    15Openness
  • PlasmidLM

    2
    University College LondonMay 19, 2026dnalanguage_modelplasmid_design+4

    Promptable DNA language model that generates multi-kilobase plasmid sequences from plain-language component specs, refined with verifiable rewards.

    DNA & Gene
    49Openness
  • PTM-dCN

    Shanghai Jiao Tong UniversityMay 11, 2026de_novo_designdiffusiongenerative+3

    Latent diffusion model for PTM-aware protein sequence design, using ControlNet-style conditioning to steer generation toward chosen PTM sites.

    Protein
    10Openness
  • GoForth

    University of California, BerkeleyMay 8, 2026encoder_decodergenerativeinverse_folding+5

    RNA inverse-folding language model that designs nucleotide sequences satisfying a target secondary structure, fixed bases, and coding constraints.

    RNA
    63Openness
  • Wisteria

    Inner Mongolia UniversityMay 7, 2026cnndnafoundation_model+6

    DNA language model combining Mamba state-space layers, gated dilated convolutions, and Fourier attention to capture multi-scale regulatory patterns.

    DNA & Gene
    10Openness
  • CodeFP

    PharMolix Inc. +1 otherMay 1, 2026de_novo_designgenerativelanguage_model+2

    Co-generative protein language model decoding sequence and structure tokens together from GO functional annotations for de novo protein design.

    Protein
    17Openness
  • Stanford UniversityApril 24, 2026bertde_novo_designdiffusion+5

    110M-parameter RNA language model that designs sequences from secondary structure, motif, and Gene Ontology constraints via discrete diffusion.

    RNA
    48Openness
  • RVQ-Alpha

    Guangzhou National LaboratoryApril 23, 2026cell_type_annotationlanguage_modelmultimodal+3

    Single-cell foundation model that tokenizes scRNA-seq into 10 tokens in a Qwen3-4B vocabulary for cell type annotation and perturbation prediction.

    Single-cell
    4Openness
  • UC BerkeleyApril 16, 2026de_novo_designdrug_discoverygenerative+4

    Molecular linker design model fine-tuned from Llama 3 that emits PROTAC and fragment linkers as SMILES from natural-language geometry prompts.

    Small molecule
    27Openness
  • AINN-P1

    AinnocenceMarch 30, 2026language_modellstmprotein_fitness_prediction+3

    Compact 167M-parameter protein language model built on a multiplicative LSTM, giving zero-shot variant effect and fitness prediction from sequence.

    Protein
    12Openness
  • Pro2RNA

    Kitasato UniversityMarch 18, 2026codon_optimizationcodon_usagelanguage_model+5

    Multimodal reverse-translation language model that generates species-aware mRNA coding sequences from protein sequences, conditioned on host taxonomy.

    RNAProtein
    10Openness