All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 100 filtered models

  • BacteReason

    University of TokyoJune 7, 2026antimicrobial_resistanceantimicrobial_resistance_predictionbacteria+5

    A reasoning LLM fine-tuned on clinical antimicrobial-susceptibility data augmented with mechanistic rationales, predicting susceptibility with explanations for novel isolate-antibiotic pairs.

    DNA & GeneLanguage model
    20Openness
  • AMix-2

    Shanghai AI Laboratory +4 othersMay 30, 2026diffusionfold_classificationfoundation_model+6

    A protein-text foundation model embedding sequences and natural language in a shared token space, enabling protein understanding and de novo design from one checkpoint.

    ProteinLanguage model
    10Openness
  • LucaPhylo

    5
    Alibaba Cloud +2 othersMay 26, 2026few_shotlanguage_modelphylogenetic_inference+5

    A hyperbolic protein language model for alignment-free phylogenetic inference, producing distance matrices for tree placement without multiple sequence alignment.

    Protein
    86Openness
  • OryzaG3

    Hainan UniversityMay 26, 2026causal_language_modeldnagenomic_variant_prediction+8

    A 700M-parameter DNA language model pretrained on the rice pangenome, built as a reusable foundation model for crop genomics and molecular breeding.

    DNA & Gene
    19Openness
  • C3P

    University of TorontoMay 24, 2026bacterial_genomeco_regulated_gene_retrievalcontrastive_learning+8

    Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.

    DNA & Gene
    77Openness
  • Albatross

    Harvard Medical SchoolMay 20, 2026ireslanguage_modelsecondary_structure_prediction+4

    An RNA language model trained by self-supervised masked-nucleotide prediction on ~50,000 IRES sequences that predicts secondary-structure features rivaling experimental chemical probing.

    RNA
    15Openness
  • ProtmRNA

    2
    Fudan University +2 othersMay 20, 2026codongene_expressionlanguage_model+7

    A cross-modal transfer-learning model that adapts the ESM-2 650M protein language model to mRNA analysis by swapping amino-acid tokens for codon tokens, applied to mRNA benchmarks without re-training.

    RNA
    11Openness
  • PlasmidLM

    University College LondonMay 19, 2026dnalanguage_modelplasmid_design+4

    A promptable DNA language model that generates multi-kilobase plasmid sequences from human-readable component specifications, post-trained with verifiable rewards.

    DNA & Gene
    49Openness
  • PTM-dCN

    Shanghai Jiao Tong UniversityMay 11, 2026controlnetde_novo_designdiffusion+5

    A latent diffusion model with ControlNet-style conditioning for post-translational-modification-aware protein sequence design.

    Protein
    10Openness
  • GoForth

    University of California, BerkeleyMay 8, 2026encoder_decodergenerativeinverse_folding+5

    A conditional encoder-decoder language model that designs RNA sequences under simultaneous secondary-structure, fixed-base, and coding constraints.

    RNA
    63Openness
  • Wisteria

    Inner Mongolia UniversityMay 7, 2026cnndnafoundation_model+6

    A pretrained DNA language model combining Mamba state-space layers, gated dilated convolutions, and Fourier-based attention to capture multi-scale genomic regulatory patterns.

    DNA & Gene
    10Openness
  • CodeFP

    PharMolix Inc. +1 otherMay 1, 2026de_novo_designgenerativelanguage_model+2

    A co-generative protein language model that jointly decodes sequence and structure tokens from GO functional annotations for de novo functional protein design.

    Protein
    17Openness
  • Stanford UniversityApril 24, 2026bertde_novo_designdiffusion+6

    A 110M-parameter multimodal RNA language model that designs RNA sequences from secondary structure, consensus, and Gene Ontology constraints via discrete diffusion.

    RNA
    48Openness
  • RVQ-Alpha

    Guangzhou National LaboratoryApril 23, 2026cell_type_annotationlanguage_modelmultimodal+5

    A Qwen3-4B language model that reads and reasons over single cells by tokenizing scRNA-seq with residual vector quantization and training with verifiable reinforcement learning.

    Single-cell
    4Openness
  • UC BerkeleyApril 16, 2026de_novo_designdrug_discoverygenerative+4

    A Llama 3 model fine-tuned on a ChEMBL corpus that designs molecular linkers from natural-language geometry and physicochemical prompts, without task-specific re-training.

    Small molecule
    27Openness
  • AINN-P1

    AinnocenceMarch 30, 2026language_modellstmprotein_fitness_prediction+3

    A compact 167M-parameter sequence-only protein language model using a multiplicative LSTM that achieves competitive ProteinGym fitness prediction without structure or attention.

    Protein
    12Openness
  • Pro2RNA

    Kitasato UniversityMarch 18, 2026codon_optimizationcodon_usagelanguage_model+5

    Multimodal reverse-translation language model that generates species-aware mRNA coding sequences from protein sequences, conditioned on host taxonomy.

    RNAProtein
    10Openness
  • SpeciefAI

    University of EdinburghMarch 16, 2026antibodyantibody_designgenerative+6

    Transformer that generates multi-species antibody and nanobody framework regions at the mRNA level, conditioned on input CDRs, across six species.

    ProteinRNA
    46Openness
  • National University of SingaporeMarch 10, 2026antibodybinding_affinity_predictionfoundation_model+6

    A paired-sequence protein language model that jointly encodes interacting proteins to predict interactions, binding affinity, and interface contacts.

    Protein
    27Openness
  • HitAnno

    Tsinghua UniversityMarch 10, 2026cell_type_annotationchromatin_accessibilitylanguage_model+4

    Hierarchical language model for atlas-level cell-type annotation of scATAC-seq data that annotates new query datasets without retraining.

    Single-cell
    14Openness
  • CALM-1.0

    1
    ETH ZurichFebruary 26, 2026antibodyantibody_designantigen+6

    Contrastive antibody language model that predicts antibody-antigen binding specificity directly from amino acid sequence using a dual-encoder, cross-attentive architecture.

    Protein
    10Openness
  • OncoBERT

    National Cancer InstituteFebruary 19, 2026bertlanguage_modeloncology+7

    BERT-style language model that learns contextual representations of somatic mutations from clinical sequencing of >210,000 patients for cancer subtyping and therapy response.

    DNA & Gene
    7Openness
  • resLens

    1
    George Washington UniversityFebruary 16, 2026antibiotic_resistance_gene_detectiongenomicslanguage_model+4

    A family of genomic language models fine-tuned from a pretrained DNA language model to detect and classify antibiotic resistance genes beyond reference-database limits.

    DNA & Gene
    11Openness
  • AntigenLM

    Chinese Academy of Sciences +1 otherFebruary 9, 2026dnafoundation_modelgenerative+5

    A structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.

    DNA & Gene
    5Openness