All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 125 filtered models
TEDlm
———Protein language model pretrained on structural domain segments, encoding fold and contact signals for remote-homology detection from sequence alone.
Protein20OpennessDrugGen 2
6—834Generative language model that designs drug-like SMILES conditioned on disease ontology and a target protein sequence for de novo drug discovery.
Small moleculeProtein51OpennessProLoc
———Text-guided localization model that grounds natural-language functional descriptions to specific residue regions of a protein sequence.
ProteinLanguage model10OpennessSingle-cell language model that prepends biomedical knowledge-graph tokens to cell sentences, grounding cell type annotation in pathway structure.
Single-cellLanguage model23OpennessBioMatrix
41—167Decoder-only foundation model that unifies sequences, 3D structures, and natural language for small molecules and proteins in one shared token space.
ProteinSmall moleculeLanguage model67OpennessDNAGPT2
———Family of ten compact GPT-2 decoder-only DNA language models spanning BPE vocabularies from 16 to 8192 tokens, built for lossless genome compression.
DNA & Gene52OpennessGermRL
1—4Reinforcement learning framework that fine-tunes the ProGen2-OAS antibody language model with GRPO to cut germline bias in generated sequences.
Protein65OpennessBacteReason
———University of TokyoJune 7, 2026antimicrobial_resistanceantimicrobial_resistance_predictionbacteria+5Reasoning LLM that predicts antimicrobial susceptibility of clinical bacterial isolates and supplies mechanistic explanations for each prediction.
DNA & GeneLanguage model20OpennessAMix-2
———Protein-text foundation model placing amino acid sequences and natural language in one token space for protein understanding and de novo design.
ProteinLanguage model10OpennessLucaPhylo
13——Hyperbolic protein language model for alignment-free phylogenetic inference, turning ESM2-650M embeddings into distance matrices for tree placement.
Protein86OpennessOryzaG3
———700M-parameter DNA language model pretrained on the rice pangenome, serving as a reusable base model for crop genomics and molecular breeding.
DNA & Gene19OpennessC3P
1——Contrastive promoter-protein pretraining that aligns bacterial promoters with their encoded proteins to learn regulatory genomics representations.
DNA & Gene77OpennessProtmRNA
2——Codon-level mRNA language model adapted from ESM-2 650M by swapping amino-acid tokens for codon tokens, transferring protein knowledge to mRNA tasks.
RNA11OpennessAlbatross
———RNA language model that predicts secondary structure of internal ribosome entry sites from sequence alone, trained on roughly 50,000 IRES sequences.
RNA15OpennessPlasmidLM
2——Promptable DNA language model that generates multi-kilobase plasmid sequences from plain-language component specs, refined with verifiable rewards.
DNA & Gene49OpennessPTM-dCN
———Latent diffusion model for PTM-aware protein sequence design, using ControlNet-style conditioning to steer generation toward chosen PTM sites.
Protein10OpennessGoForth
———RNA inverse-folding language model that designs nucleotide sequences satisfying a target secondary structure, fixed bases, and coding constraints.
RNA63OpennessWisteria
———DNA language model combining Mamba state-space layers, gated dilated convolutions, and Fourier attention to capture multi-scale regulatory patterns.
DNA & Gene10OpennessCodeFP
———Co-generative protein language model decoding sequence and structure tokens together from GO functional annotations for de novo protein design.
Protein17Openness110M-parameter RNA language model that designs sequences from secondary structure, motif, and Gene Ontology constraints via discrete diffusion.
RNA48OpennessRVQ-Alpha
———Single-cell foundation model that tokenizes scRNA-seq into 10 tokens in a Qwen3-4B vocabulary for cell type annotation and perturbation prediction.
Single-cell4OpennessLinkLlama
10115Molecular linker design model fine-tuned from Llama 3 that emits PROTAC and fragment linkers as SMILES from natural-language geometry prompts.
Small molecule27OpennessAINN-P1
———Compact 167M-parameter protein language model built on a multiplicative LSTM, giving zero-shot variant effect and fitness prediction from sequence.
Protein12OpennessPro2RNA
———Multimodal reverse-translation language model that generates species-aware mRNA coding sequences from protein sequences, conditioned on host taxonomy.
RNAProtein10Openness