University of Edinburgh

Pan-allele peptide-MHC binding prediction unifying MHC class I and II, trained on a diversity-balanced set of 214 class I and 98 class II alleles.

Transformer that generates multi-species antibody and nanobody framework regions at the mRNA level, conditioned on input CDRs, across six species.

Single-molecule localisation microscopy encoder that embeds nanoscale point clouds into a 128-dimension latent space to compare protein architecture.

Antibody caninisation model generating canine framework regions around given CDRs, released with a dataset of 430,000 canine antibody sequences.

Fragment-ion intensity prediction for cross-linked peptides, covering cleavable DSSO and DSBU chemistries alongside non-cleavable DSS and BS3.

DNA methylation foundation model over 49,156 array CpG sites. Imputes missing values, embeds samples, and predicts epigenetic age and disease risk.

Protein-ligand binding affinity prediction that fine-tunes ESM-2 and ChemBERTa-2 into a shared space where cosine similarity is the predicted pKd.