All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 289–312 of 943 models
IsoDDE
———Unified drug design engine for protein-ligand structure prediction, binding affinity estimation, and compound generation from Isomorphic Labs.
Protein13OpennessBioCLIP 2.5
77424.8KVision foundation model for the tree of life, scaling BioCLIP 2 to a ViT-H/14 backbone and more organism images for zero-shot species classification.
Imaging93OpennessEVA
——20Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.
Single-cellRNAPathology27OpennessAntigenLM
———Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.
DNA & Gene5OpennessBioLM-Score
———Shenzhen UniversityFebruary 9, 2026binding_affinity_predictiondrug_discoverymixture_density_network+4Protein-ligand scoring function that conditions probabilistic geometric potentials on language model priors to rank docked poses and binding affinity.
ProteinSmall molecule11OpennessNeuroVLM
8——Vision-language foundation model linking human brain activation maps and neuroscience text for text-to-brain and brain-to-text generation.
ImagingLanguage model74OpennessARSENAL
16——Masked DNA language model for regulatory genomics with a motif-discovery regularizer for zero-shot TF motif recovery and variant effect prediction.
DNA & Gene29OpennessE(3)-equivariant diffusion model for macrocycle design that turns acyclic molecules into macrocycles, with a transformer choosing where to cyclize.
Small molecule8OpennessProtein structure tokenizer that encodes a whole structure globally, with each successive token adding detail for adaptive-length representations.
Protein6OpennessSaDiT
—46—Protein backbone generator running a diffusion transformer over SaProt structural tokens, with an IPA token cache to speed up de novo design.
Protein5OpennessscDFM
42——Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.
Single-cell54OpennessTM-Vec 2
—1—Protein structural homology search from sequence alone, embedding proteins so that structural similarity becomes a fast nearest-neighbor lookup.
Protein4OpennessFrustrAI-Seq
71—Helmholtz MunichFebruary 5, 2026frustration_predictionintrinsically_disordered_regionsprotein_function_annotation+4Protein language model that predicts per-residue local energetic frustration directly from sequence, covering whole proteomes and disordered regions.
Protein78OpennessAdarEdit
3——Graph-attention model that predicts A-to-I RNA editing from sequence and secondary structure, treating RNA as a graph with base-pairing edges.
RNA79OpennessBioBridge
—2—Connects a frozen protein language model to a general LLM via a cross-modal projector, adding protein reasoning without catastrophic forgetting.
Language modelProtein13OpennessAtomPaint
———Full-atom SE(3)-equivariant diffusion model that inpaints binding interfaces to design proteins that bind DNA, RNA, and small molecules.
ProteinSmall molecule19OpennessDecoderTCR
8——Masked language model for T-cell receptor and peptide-MHC binding prediction, with compositional pretraining and non-autoregressive decoding.
Protein56OpennessNUWA
———mRNA language foundation model trained on ~115M protein-coding sequences across the tree of life, unifying mRNA perception and generation.
RNADNA & Gene16OpennessPert2Mol
—7—Multimodal model that designs small molecules from transcriptomic and cell-imaging perturbation phenotypes with a rectified flow transformer.
Small moleculeSingle-cell22OpennessscDiVa
—2—Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.
Single-cell6OpennessEchoJEPA
3284—Joint-embedding predictive foundation model for echocardiography, pretrained on 18M cardiac ultrasound videos for artifact-robust representations.
Imaging62OpennessevoRate
———Genome language model that adds evolutionary-rate prediction to pretraining, improving representations for variant effect and regulatory genomics.
DNA & Gene14OpennessCHASE
———Latent flow-matching method that repurposes protein language model embeddings to generate high-fitness protein variants without predictor guidance.
Protein11OpennessMoLF
———Pan-cancer model predicting spatial gene expression from H&E histology using conditional flow matching with a mixture-of-experts velocity field.
PathologySpatial omics9Openness