All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 289312 of 943 models

  • IsoDDE

    Isomorphic LabsFebruary 10, 2026binding_affinity_predictiondiffusiondrug_discovery+6

    Unified drug design engine for protein-ligand structure prediction, binding affinity estimation, and compound generation from Isomorphic Labs.

    Protein
    13Openness
  • BioCLIP 2.5

    77424.8K
    Imageomics InstituteFebruary 10, 2026biodiversitycontrastive_learningfoundation_model+6

    Vision foundation model for the tree of life, scaling BioCLIP 2 to a ViT-H/14 backbone and more organism images for zero-shot species classification.

    Imaging
    93Openness
  • EVA

    20
    Scienta LabFebruary 10, 2026embeddingsfoundation_modelgene_expression+9

    Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.

    Single-cellRNAPathology
    27Openness
  • AntigenLM

    Chinese Academy of Sciences +1 otherFebruary 9, 2026dnafoundation_modelgenerative+5

    Structure-aware generative DNA language model pretrained on influenza genomes that forecasts future antigenic variants across regions and subtypes.

    DNA & Gene
    5Openness
  • BioLM-Score

    Shenzhen UniversityFebruary 9, 2026binding_affinity_predictiondrug_discoverymixture_density_network+4

    Protein-ligand scoring function that conditions probabilistic geometric potentials on language model priors to rank docked poses and binding affinity.

    ProteinSmall molecule
    11Openness
  • NeuroVLM

    8
    University of California, San DiegoFebruary 9, 2026autoencoderbrain_decodingcontrastive_learning+2

    Vision-language foundation model linking human brain activation maps and neuroscience text for text-to-brain and brain-to-text generation.

    ImagingLanguage model
    74Openness
  • ARSENAL

    16
    Stanford UniversityFebruary 6, 2026chromatinlanguage_modelmotif_discovery+6

    Masked DNA language model for regulatory genomics with a motif-discovery regularizer for zero-shot TF motif recovery and variant effect prediction.

    DNA & Gene
    29Openness
  • Keshav Memorial Engineering CollegeFebruary 6, 2026diffusiondrug_discoverygenerative+3

    E(3)-equivariant diffusion model for macrocycle design that turns acyclic molecules into macrocycles, with a transformer choosing where to cyclize.

    Small molecule
    8Openness
  • CaltechFebruary 6, 2026autoencoderprotein_designprotein_structure+4

    Protein structure tokenizer that encodes a whole structure globally, with each successive token adding detail for adaptive-length representations.

    Protein
    6Openness
  • SaDiT

    46
    Independent ResearcherFebruary 6, 2026de_novo_designdiffusiongenerative+3

    Protein backbone generator running a diffusion transformer over SaProt structural tokens, with an IPA token cache to speed up de novo design.

    Protein
    5Openness
  • scDFM

    42
    Westlake UniversityFebruary 6, 2026flow_matchinggene_expressiongenerative+4

    Single-cell perturbation prediction model using conditional flow matching to map control cells to perturbed expression distributions.

    Single-cell
    54Openness
  • TM-Vec 2

    1
    Arizona State UniversityFebruary 5, 2026embeddingshomology_detectionproteomics+3

    Protein structural homology search from sequence alone, embedding proteins so that structural similarity becomes a fast nearest-neighbor lookup.

    Protein
    4Openness
  • Helmholtz MunichFebruary 5, 2026frustration_predictionintrinsically_disordered_regionsprotein_function_annotation+4

    Protein language model that predicts per-residue local energetic frustration directly from sequence, covering whole proteomes and disordered regions.

    Protein
    78Openness
  • AdarEdit

    3
    Stanford University +1 otherFebruary 4, 2026a_to_i_editingcnngraph_attention_network+5

    Graph-attention model that predicts A-to-I RNA editing from sequence and secondary structure, treating RNA as a graph with base-pairing edges.

    RNA
    79Openness
  • BioBridge

    2
    Tongji University +1 otherFebruary 4, 2026continual_learninglanguage_modelmultimodal+5

    Connects a frozen protein language model to a general LLM via a cross-modal projector, adding protein reasoning without catastrophic forgetting.

    Language modelProtein
    13Openness
  • AtomPaint

    Harvard Medical SchoolFebruary 4, 2026binder_designdiffusiongenerative+4

    Full-atom SE(3)-equivariant diffusion model that inpaints binding interfaces to design proteins that bind DNA, RNA, and small molecules.

    ProteinSmall molecule
    19Openness
  • DecoderTCR

    8
    Biohub +1 otherFebruary 4, 2026contrastive_learningfoundation_modelimmune_repertoire_analysis+5

    Masked language model for T-cell receptor and peptide-MHC binding prediction, with compositional pretraining and non-autoregressive decoding.

    Protein
    56Openness
  • NUWA

    Kitasato UniversityFebruary 4, 2026bertfoundation_modellanguage_model+5

    mRNA language foundation model trained on ~115M protein-coding sequences across the tree of life, unifying mRNA perception and generation.

    RNADNA & Gene
    16Openness
  • Pert2Mol

    7
    Purdue UniversityFebruary 4, 2026de_novo_designgenerativemolecular_generation+5

    Multimodal model that designs small molecules from transcriptomic and cell-imaging perturbation phenotypes with a rectified flow transformer.

    Small moleculeSingle-cell
    22Openness
  • scDiVa

    2
    Renmin University of ChinaFebruary 3, 2026batch_integrationcell_type_annotationdiffusion+6

    Single-cell foundation model built on masked discrete diffusion, jointly generating gene identities and expression values from 59 million cells.

    Single-cell
    6Openness
  • EchoJEPA

    3284
    Bowang LabFebruary 2, 2026cardiac_ultrasoundechocardiographyejection_fraction_estimation+6

    Joint-embedding predictive foundation model for echocardiography, pretrained on 18M cardiac ultrasound videos for artifact-robust representations.

    Imaging
    62Openness
  • evoRate

    University of TorontoFebruary 2, 2026genomicsmolecular_evolutionregulatory_genomics+4

    Genome language model that adds evolutionary-rate prediction to pretraining, improving representations for variant effect and regulatory genomics.

    DNA & Gene
    14Openness
  • CHASE

    ETH Zurich +1 otherFebruary 2, 2026autoencoderdirected_evolutionfitness_optimization+4

    Latent flow-matching method that repurposes protein language model embeddings to generate high-fitness protein variants without predictor guidance.

    Protein
    11Openness
  • MoLF

    National Center for Tumor Diseases DresdenFebruary 2, 2026flow_matchinggene_expressiongenerative+5

    Pan-cancer model predicting spatial gene expression from H&E histology using conditional flow matching with a mixture-of-experts velocity field.

    PathologySpatial omics
    9Openness