All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 265288 of 943 models

  • MACE-POLAR-1

    75
    University of CambridgeFebruary 23, 2026drug_discoveryequivariant_neural_networkfoundation_model+5

    Polarizable machine-learning interatomic potential extending MACE with long-range electrostatics, trained on 100M OMol25 DFT calculations.

    Small moleculeProtein
    19Openness
  • PerturbDiff

    52
    MilaFebruary 23, 2026diffusiongene_expressiongenerative+3

    Diffusion model predicting single-cell responses to genetic or drug perturbations, generating over distributions to capture population variability.

    Single-cell
    51Openness
  • PLUM

    1
    Iowa State UniversityFebruary 21, 2026antimicrobial_peptidesde_novo_designgenerative+3

    Conditional variational autoencoder for antimicrobial peptide design that disentangles sequence, function, and length for independent control.

    Protein
    56Openness
  • PEINT

    18
    UC BerkeleyFebruary 20, 2026evolutionary_simulationgenerativemolecular_evolution+4

    Protein evolution model that learns indel dynamics and epistasis from unaligned sequences, simulating trajectories that yield functional proteins.

    Protein
    11Openness
  • University of BristolFebruary 19, 2026data_generationdiffusionfoundation_model+4

    Single-cell foundation model applying discrete diffusion directly to scRNA-seq counts, generating unconditional and perturbation-conditioned profiles.

    Single-cell
    10Openness
  • JEPA-DNA

    13
    NVIDIAFebruary 19, 2026dnafoundation_modelgenomics+5

    Genomic foundation model training framework whose joint-embedding predictive objective learns functional representations of masked DNA, not tokens.

    DNA & Gene
    54Openness
  • OncoBERT

    88
    National Cancer InstituteFebruary 19, 2026bertlanguage_modeloncology+7

    BERT-style language model for somatic mutations, pretrained on cancer sequencing from 210,000+ patients for tumor subtyping and therapy response.

    DNA & Gene
    7Openness
  • CLM-X

    Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6

    Multimodal single-cell foundation model whose multiway Transformer jointly models scRNA-seq and scATAC-seq from RNA-only, ATAC-only, or paired inputs.

    Single-cell
    4Openness
  • BOND-PEP

    University of SydneyFebruary 18, 2026de_novo_designgenerativepeptides+3

    Retrieval-augmented framework for de novo peptide binder design that conditions generation on retrieved, structurally aligned binding evidence.

    Protein
    5Openness
  • MMPT-RAG

    1
    Emory UniversityFebruary 18, 2026drug_discoveryfoundation_modelgenerative+3

    Retrieval-augmented model for matched molecular pair transformations, proposing localized analog edits guided by retrieved reference compounds.

    Small molecule
    16Openness
  • Columbia UniversityFebruary 17, 2026dna_methylationepigenomicsfoundation_model+4

    Transformer that infers whole-genome DNA methylation from gene expression, generalizing zero-shot to unmeasured CpG sites and unseen samples.

    DNA & Gene
    10Openness
  • ProtFlow

    2
    Zhejiang UniversityFebruary 17, 2026antimicrobial_peptidesde_novo_designflow_matching+4

    Flow-matching generative model for peptide sequence design that learns the protein semantic distribution, fine-tuned for antimicrobial peptides.

    Protein
    16Openness
  • Florida International UniversityFebruary 17, 2026cheminformaticsdebertafoundation_model+4

    SMILES molecular encoder on a DeBERTaV2 backbone, pretrained on 123M PubChem molecules with physicochemical and structural-similarity objectives.

    Small molecule
    25Openness
  • resLens

    3
    George Washington UniversityFebruary 16, 2026genomicslanguage_modelmetagenomics+3

    Genomic language models fine-tuned to detect and classify antibiotic resistance genes, catching divergent ARGs that reference alignment misses.

    DNA & Gene
    11Openness
  • BioKinema

    3
    International Digital Economy AcademyFebruary 15, 2026conformational_samplingdiffusiondrug_discovery+5

    Diffusion model that generates continuous-time, all-atom biomolecular trajectories, reproducing conformational kinetics far more cheaply than MD.

    ProteinSmall molecule
    13Openness
  • SEAL

    48121
    Mahmood Lab +2 othersFebruary 15, 2026cancer_subtypingfoundation_modelgene_expression_prediction+5

    Vision-omics finetuning that aligns pathology foundation models with spatial transcriptomics so morphology features predict local gene expression.

    PathologySpatial omics
    32Openness
  • evoCancerGPT

    Dana-Farber Cancer InstituteFebruary 14, 2026cancerfoundation_modelgene_expression+5

    Single-cell foundation model that forecasts how cancer cells evolve, autoregressively generating future gene expression from prior cell states.

    Single-cell
    11Openness
  • Tsinghua UniversityFebruary 14, 2026autoregressivecell_biologyde_novo_design+7

    Protein language model that encodes sequences as discrete words from a learned vocabulary for zero-shot function inference and protein design.

    Protein
    24Openness
  • Tsinghua UniversityFebruary 13, 2026chiralityde_novo_designdiffusion+5

    Latent diffusion model that designs D-peptide binders against native L-protein targets, generalizing across chirality via axial vector features.

    Protein
    67Openness
  • IQuestLabFebruary 13, 2026curriculum_learningfoundation_modelmolecular_dynamics

    Universal all-atom machine-learning force field for molecular dynamics, with ab initio-level accuracy on solvated biomolecules of ~1,500 atoms.

    Small moleculeProtein
    81Openness
  • STPAINTER

    61
    University of Science and Technology of China +2 othersFebruary 13, 2026cancerdiffusionfoundation_model+4

    Pan-cancer pretrained diffusion model imputing genome-wide expression from sparse spatial transcriptomics panels, zero-shot and reference-free.

    Spatial omicsSingle-cell
    4Openness
  • DERIVE

    Guangzhou National LaboratoryFebruary 12, 2026flow_matchingfoundation_modelgenerative+5

    Multimodal generative model predicting viral antigenic change zero-shot from disentangled evolutionary, physicochemical, and structural signals.

    Protein
    16Openness
  • TerraBind

    1
    Terray TherapeuticsFebruary 12, 2026binding_affinitydrug_discoveryfoundation_model+3

    Protein-ligand foundation model that maps coarse-grained structural representations directly to binding affinity, running ~26x faster than Boltz-2.

    ProteinSmall molecule
    24Openness
  • dnaHNet

    2
    Arc Institute +2 othersFebruary 11, 2026dnafoundation_modelgene_essentiality_prediction+7

    Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.

    DNA & Gene
    12Openness