Nanjing University

Text-guided localization model that grounds natural-language functional descriptions to specific residue regions of a protein sequence.

Diffusion-based generative RNA model for de novo sequence design, conditioned on function, RNA family, structure, or binding proteins.

Tri-modal foundation model unifying histology images, spatial transcriptomics, and language for zero-shot pathology and spatial biology reasoning.

Enzyme design model that jointly generates enzyme sequences and substrate-binding pockets, conditioned on functional priors and substrate structure.

Retrieval-augmented diffusion model for protein inverse folding that conditions sequence generation on profiles from structurally similar homologs.