All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 2548 of 73 filtered models

  • EVA

    821
    GENTEL LabMarch 24, 2026aptameraptamer_designcircular_rna+9

    Generative RNA foundation model trained on 114 million full-length sequences for de novo design of tRNAs, aptamers, CRISPR guide RNAs, and mRNAs.

    RNA
    72Openness
  • ZeroFold

    University of Cambridge +1 otherMarch 24, 2026binding_affinity_predictioncross_attentiondrug_discovery+3

    Transformer that predicts protein-RNA binding affinity from Boltz-2 pre-structural embeddings via cross-modal attention, with no 3D structure step.

    RNAProtein
    23Openness
  • ChironRNA

    University of VirginiaMarch 19, 2026diffusiongenerativegraph_neural_network+3

    All-atom E(3)-equivariant diffusion model that refines RNA structures by resolving steric clashes and completing missing atoms.

    RNA
    19Openness
  • Pro2RNA

    Kitasato UniversityMarch 18, 2026codon_optimizationcodon_usagelanguage_model+5

    Multimodal reverse-translation language model that generates species-aware mRNA coding sequences from protein sequences, conditioned on host taxonomy.

    RNAProtein
    10Openness
  • RNAElectra

    Australian National UniversityMarch 17, 2026foundation_modelself_supervisedstructure_prediction+1

    Single-nucleotide-resolution RNA foundation model pretrained on non-coding RNAs with ELECTRA-style replaced-token detection for regulatory inference.

    RNA
    23Openness
  • ATOMICA

    3
    Harvard UniversityMarch 16, 2026binding_site_predictionfoundation_modelgraph_neural_network+6

    Geometric deep learning model that learns atomic-scale representations of molecular interfaces across proteins, small molecules, and nucleic acids.

    ProteinSmall moleculeRNA
    88Openness
  • SpeciefAI

    University of EdinburghMarch 16, 2026antibodyantibody_designgenerative+5

    Transformer that generates multi-species antibody and nanobody framework regions at the mRNA level, conditioned on input CDRs, across six species.

    ProteinRNA
    46Openness
  • CDS-BART

    9
    MOGAM Institute for Biomedical ResearchMarch 12, 2026bartfoundation_modelgene_expression+5

    Coding-sequence foundation model for mRNA design, pretrained as a BART denoising encoder-decoder on mRNA from nine taxonomic groups.

    RNA
    63Openness
  • EVA

    89
    Scienta LabFebruary 10, 2026embeddingsfoundation_modelgene_expression+9

    Cross-species multimodal foundation model of immunology and inflammation, harmonizing transcriptomics and histology into patient-level embeddings.

    Single-cellRNAPathology
    27Openness
  • AdarEdit

    3
    Stanford University +1 otherFebruary 4, 2026a_to_i_editingcnngraph_attention_network+5

    Graph-attention model that predicts A-to-I RNA editing from sequence and secondary structure, treating RNA as a graph with base-pairing edges.

    RNA
    79Openness
  • NUWA

    Kitasato UniversityFebruary 4, 2026bertfoundation_modellanguage_model+5

    mRNA language foundation model trained on ~115M protein-coding sequences across the tree of life, unifying mRNA perception and generation.

    RNADNA & Gene
    16Openness
  • Nobuyuki OtaJanuary 3, 2026cell_biologygene_expressiongenomics+4

    Multimodal architecture coupling pretrained DNA, RNA, and protein language models with directional cross-attention into one Virtual Cell Embedding.

    DNA & GeneRNAProtein
    22Openness
  • Kitasato University +2 othersDecember 24, 2025codoncodon_optimizationfoundation_model+7

    GPT-style generative language model for mRNA coding sequences, pretrained across bacteria, eukaryotes, and archaea for de novo CDS design.

    RNA
    39Openness
  • Helix

    3
    Shape TherapeuticsDecember 20, 2025a_to_i_editingguide_rna_designknowledge_distillation+4

    Structure-aware transformer that makes zero-shot, per-adenosine predictions of ADAR-mediated A-to-I RNA editing to guide therapeutic guide-RNA design.

    RNA
    4Openness
  • cfRNA-ICL

    Eigen BioDecember 13, 2025cancer_classificationcell_free_rnaearly_cancer_detection+7

    In-context learning model for cell-free RNA, meta-trained on synthetic tasks from a cfRNA structural causal model for few-shot cancer classification.

    Single-cellRNA
    8Openness
  • gRNAde

    310321
    MRC Laboratory of Molecular Biology +1 otherDecember 1, 2025de_novo_designgenerativegraph_neural_network+5

    RNA inverse-folding model that generates sequences predicted to fold into a target 3D backbone, capturing non-canonical pairs and tertiary motifs.

    RNA
    98Openness
  • Tongji University +1 otherNovember 28, 2025cell_type_annotationfoundation_modelgene_expression+6

    Single-cell foundation model adapting LLaMA-3.1-8B with LoRA, recasting transcriptomes and protein interaction networks as natural-language Q&A pairs.

    Single-cellRNA
    55Openness
  • RNA-X

    41
    Bilkent UniversityNovember 26, 2025de_novo_designfoundation_modelmasked_language_model+5

    RNA interaction foundation model for conditional, zero-shot design of RNA sequences that bind protein, DNA, or RNA targets without retraining.

    RNAProtein
    6Openness
  • University of Maryland, College ParkNovember 24, 2025codon_optimizationde_novo_designfoundation_model+6

    Conditional codon language model with 150M parameters that generates species-optimized coding sequences from a protein and its taxonomic lineage.

    DNA & GeneRNA
    90Openness
  • Nona

    3
    GenentechNovember 6, 2025discrete_diffusionfoundation_modelfunctional_genomics+8

    Genomics foundation model that unifies sequence-to-function prediction, DNA language modeling, and generative regulatory design in one backbone.

    DNA & GeneRNA
    8Openness
  • OpenFold3

    7961
    Aqlaboratory +2 othersOctober 28, 2025diffusiondrug_discoveryfoundation_model+2

    Open-source Apache-2.0 reproduction of AlphaFold3 that predicts all-atom structures of proteins, RNA, DNA, small molecules, and their complexes.

    ProteinRNASmall molecule
    92Openness
  • FlashRNA

    182
    Deep GenomicsOctober 15, 2025foundation_modelgene_expressiongenomics+4

    Efficient sequence-to-function transformer for regulatory genomics, matching Borzoi-class models while training in about a day on a single GPU.

    DNA & GeneRNA
    59Openness
  • University of Science and Technology of ChinaAugust 7, 2025bertfoundation_modellanguage_model+8

    RNA foundation model pretrained jointly on sequences and secondary structures for structure prediction, homology and splice site classification.

    RNA
    92Openness
  • MOJO

    4045
    InstaDeepJune 25, 2025bertdna_methylationfoundation_model+7

    Bimodal masked language model that jointly encodes bulk RNA-seq expression and DNA methylation into patient-level embeddings for cancer genomics.

    RNADNA & Gene
    29Openness