All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 25–48 of 78 filtered models
FOCUS
———Generative foundation model that imputes genes and denoises spatial transcriptomics, conditioned on H&E histology, scRNA-seq, and spatial priors.
Spatial omicsPathologySingle-cell4OpennessM-Optimus
———Multimodal foundation model that embeds histology, transcriptomics, and clinical records in one space for patient stratification and target discovery.
PathologySpatial omicsSingle-cell3OpennessEXAONE Path 2.5
5280Pathology foundation model that aligns whole-slide images with genomic, epigenetic, and transcriptomic data for patient-level tumor representations.
PathologySpatial omics14OpennessEva
—4—Enable Medicine +4 othersDecember 12, 2025cell_type_annotationcross_modal_inferencefoundation_model+8Tissue imaging foundation model pretrained on matched H&E histology and spatial proteomics for cross-modal inference and zero-shot retrieval.
PathologySpatial omics4OpennessSIGMMA
—1—Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.
PathologySpatial omics20OpennessSHEST
1——Samsung Advanced Institute for Health Sciences and Technology +2 othersNovember 19, 2025cell_type_annotationgene_expressionhistology+5Histopathology model that predicts single-cell type composition and reconstructs spatial gene expression from H&E slides, with no molecular assay.
PathologySpatial omics16OpennessUni-Hema
—1—Information Technology University of the Punjab +1 otherNovember 18, 2025classificationcnnfoundation_model+8Digital hematopathology foundation model unifying blood-cell detection, classification, segmentation, and visual question answering.
Pathology8OpennessJWTH
—1—Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.
Pathology5OpennessGPFM
12954—Hong Kong University of Science and Technology +3 othersNovember 1, 2025cancer_diagnosisfeature_extractionfoundation_model+8Histopathology foundation model extracting general-purpose features from H&E patches by distilling the UNI, Phikon, and CONCH pathology encoders.
Pathology84OpennessPathQC
1——Pan-tissue quality-control model that predicts RNA integrity and autolysis from H&E whole-slide images using frozen UNI foundation model embeddings.
Pathology25OpennessDeepSpot2Cell
152—Predicts virtual single-cell spatial transcriptomics from H&E histology using frozen pathology foundation models and spot-level supervision.
PathologySpatial omics58OpennessHistology vision transformer with 80M parameters that predicts spatial gene expression from H&E tissue images and transfers to tumor detection.
PathologySpatial omics59OpennessABMIL
1522.7K42Attention-based multiple instance learning heads for whole-slide pathology, pretrained on a 108-way pan-cancer slide classification task.
Pathology26OpennessMedSigLIP
29837421KMedically tuned SigLIP encoder from Google that maps medical images and text into one embedding space for zero-shot classification and retrieval.
ImagingPathology30OpennessChiron-o1
601421Medical multimodal LLM (2B and 8B) trained for generalizable, step-by-step clinical reasoning via Mentor-Intern Collaborative Search.
PathologyImaging67OpennessKRONOS
20432582Spatial proteomics foundation model, marker-aware and panel-agnostic, pretrained on 47 million multiplexed tissue-imaging patches from 175 markers.
Spatial omicsPathology12OpennessBEPH
7797—Histopathology foundation model pretrained with BEiT masked image modeling on 11M+ tissue image tiles for cancer diagnosis and survival prediction.
Pathology73OpennessSpatialEx
38——Jilin University +1 otherFebruary 23, 2025contrastive_learningfoundation_modelgene_expression_prediction+6Histology-anchored framework pairing an H&E foundation model with a cellular hypergraph to predict single-cell multi-omics from tissue images.
Spatial omicsPathology57OpennessHealthGPT
1.6K11538Zhejiang University +4 othersFebruary 14, 2025histologyimage_reconstructionmedical_image_generation+7Medical vision-language model that unifies image comprehension and generation in one autoregressive transformer via heterogeneous LoRA adapters.
PathologyImaging68OpennessMUSK
240283—Vision-language foundation model for precision oncology, pretrained on 50M pathology images and 1B text tokens via unified masked modeling.
PathologyLanguage model12OpennessBiMediX2
742120Mohamed bin Zayed University of Artificial IntelligenceDecember 10, 2024histologyinstruction_tuninglanguage_model+7Bilingual Arabic-English medical multimodal model built on Llama 3.1 for radiology, CT, and histology image understanding and question answering.
Language modelImagingPathology11OpennessTITAN
357218118.2KSlide-level pathology foundation model turning whole-slide images into reusable embeddings for classification, retrieval, and report generation.
Pathology21OpennessMedRegA
462913Hong Kong University of Science and Technology +1 otherOctober 24, 2024histologyimage_classificationinstruction_tuning+8Region-aware bilingual medical multimodal LLM that handles image- and region-level vision-language tasks across eight imaging modalities.
PathologyLanguage model65Openness