All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–20 of 20 filtered models
LDARNet
—1—A 120M-parameter genomic foundation model that learns adaptive DNA token boundaries via H-Net-style dynamic chunking instead of fixed k-mer or byte-pair tokenization.
DNA & Gene26OpennessWisteria
———A pretrained DNA language model combining Mamba state-space layers, gated dilated convolutions, and Fourier-based attention to capture multi-scale genomic regulatory patterns.
DNA & Gene10OpennessMach-1
—4—Long-context (64 kb) RNA foundation model using the Striped-Hyena architecture for zero-shot prediction of transcriptome architecture from unspliced pre-mRNA sequence.
RNA39Opennessseq2ribo
81—A hybrid simulation and machine-learning framework that predicts ribosome location profiles from mRNA sequence alone, combining a structure-aware TASEP with a Mamba polisher.
RNA18OpennessPlantCAD2
894—A long-context plant DNA language model (676M params, Mamba2) pretrained on 65 angiosperm genomes for cross-species functional annotation.
DNA & Gene69OpennessRegFormer
—8—GRN-informed single-cell foundation model combining gene regulatory hierarchy priors with long-sequence Mamba modeling for clustering, batch integration, perturbation modeling, and drug response prediction.
Single-cell10OpennessPI-Mamba
———Physics-informed generative model that pairs flow matching with a Mamba state-space backbone for linear-time protein backbone design, scaling to 2,000+ residues.
Protein23OpennessFishMamba-1
——9Institute of Hydrobiology, Chinese Academy of SciencesMarch 9, 2026dnafoundation_modelgenome_annotation+4Genomic foundation model for Cypriniformes fish, built on a Mamba-2 state space model with a 32 kb context window for long-range genome modeling.
DNA & Gene50OpennessGeneralist EEG-to-text foundation model that translates EEG segments into clinically grounded natural-language descriptions via spectro-spatial grounding and state-space reasoning.
Biosignals18OpennessA 2.6B-parameter Liquid Foundation Model fine-tuned via Insilico's MMAI Gym to handle ADMET, retrosynthesis, drug-target activity, and molecular optimization in one checkpoint.
Small moleculeLanguage model7OpennessdnaHNet
—1—A tokenizer-free, hierarchical autoregressive genomic foundation model that adaptively chunks raw nucleotides, enabling efficient long-context learning and zero-shot variant and gene predictions.
DNA & Gene12OpennessPlantBiMoE
———A lightweight plant genome foundation model pairing a bidirectional Mamba backbone with a sparse Mixture-of-Experts, pretrained on 25.4B nucleotides from 42 plant species.
DNA & Gene53OpennessPanFoMa
———A lightweight pan-cancer single-cell foundation model with a hybrid Transformer-Mamba architecture, released alongside the PanFoMaBench benchmark.
Single-cell13OpennesseccDNAMamba
5——Bidirectional state-space (Mamba-2) genomic model for ultra-long extrachromosomal circular DNA, scaling linearly with sequence length.
DNA & Gene54OpennessEMReady2
12——A Mamba-based dual-branch UNet that enhances cryo-EM and cryo-ET density maps using local resolution-guided learning to improve interpretability.
Imaging54OpennessApple's foundation model trained on behavioral signals from wearables, modeling 27 HealthKit metrics to improve predictions across 57 health tasks.
Biosignals7OpennessNeuroSTORM
1133—A spatiotemporal foundation model that learns generalizable representations directly from 4D functional MRI volumes for diverse brain-imaging tasks.
ImagingBiosignals78OpennessA foundational fMRI model that learns brain dynamics via stochastic optimal control, pretrained self-supervised on resting-state scans from 41,072 UK Biobank subjects.
Biosignals8OpennessCaduceus
24021019.7KBidirectional, reverse-complement equivariant DNA language models built on Mamba SSMs. Outperforms models 10x larger on long-range variant effect prediction.
DNA & Gene86Openness