Guangzhou Medical University

Diffusion super-resolution for H&E whole-slide images, steering denoising with SAM-derived structural anchors and adapted DINOv3 semantic control.

Generative antibody and nanobody design model that co-designs CDR sequences and antigen-bound structures for de novo design and affinity maturation.

Multimodal single-cell foundation model pretrained on 4M+ co-assayed cells, predicting 382 surface proteins from transcriptomes alone, zero-shot.

Single-cell DNA methylation foundation model capturing genome-wide CpG dependencies in whole-genome bisulfite sequencing across tissues and species.

Multiomic foundation model for zero-shot in silico perturbation, predicting gene regulation and cell fate transitions from DNA and ATAC signal.