All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 26 filtered models

  • LEAF-1

    McGill University +1 otherJuly 10, 2026cancer_detectioncell_type_annotationcfdna+5

    Genomics foundation model that represents individual DNA fragments in a learned semantic space for cell-free DNA cancer detection and cell typing.

    DNA & GeneSingle-cell
    4Openness
  • Zhejiang Lab +1 otherApril 21, 2026chromatinchromatin_accessibilitydna+8

    Genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window and a 1.25B-parameter mixture-of-experts transformer.

    DNA & Gene
    90Openness
  • Deep-Plant

    1
    Colorado State University +1 otherApril 9, 2026chromatincnnenhancer_prediction+6

    Chromatin-informed foundation model predicting regulatory activity and chromatin state directly from plant genomic sequence in Arabidopsis and rice.

    DNA & Gene
    87Openness
  • ARCH3D

    University of MichiganFebruary 25, 20263d_genomechromatincontact_map_reconstruction+5

    Foundation model for 3D genome architecture, using masked locus modeling over genome-wide contact profiles to capture chromosome-scale organization.

    DNA & Gene
    19Openness
  • ChIANet

    Central South UniversityFebruary 25, 20263d_genomechromatinchromatin_contact_prediction+4

    Multimodal deep learning model that predicts protein-mediated chromatin contact maps and loops de novo from protein-binding profiles and sequence.

    DNA & Gene
    10Openness
  • CLM-X

    Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6

    Multimodal single-cell foundation model whose multiway Transformer jointly models scRNA-seq and scATAC-seq from RNA-only, ATAC-only, or paired inputs.

    Single-cell
    4Openness
  • ARSENAL

    16
    Stanford UniversityFebruary 6, 2026chromatinlanguage_modelmotif_discovery+6

    Masked DNA language model for regulatory genomics with a motif-discovery regularizer for zero-shot TF motif recovery and variant effect prediction.

    DNA & Gene
    29Openness
  • GenoME

    1
    Changping Laboratory +1 otherDecember 28, 2025chromatinepigenomicsfoundation_model+8

    Mixture-of-Experts generative model turning DNA sequence plus cell-type ATAC-seq into unified epigenomic, transcriptomic, and 3D chromatin profiles.

    DNA & GeneSingle-cell
    8Openness
  • Puget

    University of WashingtonNovember 20, 2025chromatindnafoundation_model+6

    Gene expression prediction model combining DNA sequence with Hi-C contact maps to capture 3D chromatin looping behind cell-type-specific expression.

    DNA & Gene
    8Openness
  • Evo2HiC

    102
    University of WashingtonNovember 19, 2025chromatinchromatin_contact_predictionepigenomic_profiling+9

    Multimodal foundation model that distills Evo 2 into a compact encoder guided by Hi-C data, predicting cell-type-specific 3D genome architecture.

    DNA & GeneSpatial omics
    57Openness
  • University of VirginiaNovember 4, 2025batch_correctioncell_type_annotationchromatin+7

    Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.

    Single-cellDNA & Gene
    32Openness
  • Scooby

    6912463
    Technical University of Munich +4 othersOctober 1, 2025chromatinchromatin_accessibility_predictionconvolutional_neural_network+5

    Predicts single-cell scRNA-seq coverage and scATAC-seq insertion profiles from DNA sequence, adapting the Borzoi trunk with a cell-specific decoder.

    Single-cell
    70Openness
  • Broad InstituteAugust 17, 2025chromatinfoundation_modelgene_regulation+7

    Multimodal foundation model predicting genome-wide binding of chromatin-associated proteins from protein sequence, DNA sequence, and chromatin state.

    DNA & GeneProtein
    25Openness
  • GREmLN

    38
    Chan Zuckerberg Initiative +2 othersJuly 9, 2025cell_type_annotationchromatinfoundation_model+6

    Single-cell transcriptomics foundation model that encodes gene regulatory network structure into self-attention through graph signal processing.

    Single-cell
    80Openness
  • AlphaGenome

    2K154
    Google DeepMindJune 27, 2025chromatinfoundation_modelgene_expression+4

    DNA foundation model that predicts thousands of functional genomic tracks, from expression and splicing to chromatin, at single base-pair resolution.

    DNA & Gene
    49Openness
  • Harvard Medical School +1 otherNovember 12, 2024chromatingene_expressiongenomics+4

    Conditional autoregressive genomic language model trained on 13.6M mammalian promoters, scoring promoter variants, including indels, zero-shot.

    DNA & Gene
    89Openness
  • University of TokyoJuly 25, 2024bertchromatinchromatin_state_modeling+7

    Chromatin-state language model pretrained on ROADMAP annotations from 127 human cell types to find chromatin-state motifs and predict gene expression.

    DNA & Gene
    86Openness
  • Puffin

    10655
    UT Southwestern Medical CenterApril 26, 2024chromatincnngene_expression+3

    Interpretable model of human transcription initiation that decomposes promoter activity into a minimal set of sequence rules at base-pair resolution.

    DNA & Gene
    23Openness
  • EpiGePT

    3311
    Tsinghua UniversityJuly 18, 2023chromatinepigenomicsfoundation_model+2

    Transformer model predicting context-specific epigenomic signals across cell types using DNA sequence and transcription factor activity profiles.

    DNA & Gene
    65Openness
  • Hunan Normal UniversityDecember 14, 2022chromatindeep_learningepigenomic_prediction+4

    Gene expression prediction from histone modifications, combining self-attention with dense convolutions and transfer learning across cell types.

    DNA & Gene
    22Openness
  • Seoul National UniversityNovember 4, 2022chromatindeep_learningepigenomic_prediction+4

    Transformer predicting gene expression from histone modifications, using promoter-enhancer Hi-C interactions to capture distal regulatory effects.

    DNA & Gene
    71Openness
  • GeneBERT

    27
    Carnegie Mellon UniversityOctober 11, 2021bertchromatinfoundation_model+6

    Multi-modal self-supervised transformer for regulatory genomics, pre-trained on DNA sequence together with transcription factor binding matrices.

    DNA & Gene
    18Openness
  • Basenji2

    473225
    Calico Life SciencesAugust 6, 2020chromatincnngene_expression+5

    Cross-species convolutional network trained jointly on human and mouse genomes to predict regulatory sequence activity and noncoding variant effects.

    DNA & Gene
    79Openness
  • Basenji

    473515
    Calico Life SciencesMay 1, 2018chromatincnngene_expression+4

    Dilated convolutional network that predicts cell-type-specific epigenetic and transcriptional profiles from DNA sequence across mammalian genomes.

    DNA & Gene
    73Openness