All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 124 of 24 filtered models

  • RegVelo

    1538
    Helmholtz MunichMay 11, 2026cell_fate_mappingchromatingene_regulatory_network_inference+6

    Bayesian deep generative model that integrates gene regulatory networks into RNA velocity inference, enabling cell fate mapping and in silico perturbation of transcription factors.

    Single-cell
    59Openness
  • Zhejiang Lab +1 otherApril 21, 2026chromatinchromatin_accessibilitydna+8

    A 1.25B-parameter Mixture-of-Experts genomic foundation model for rice, pretrained on 422 Oryza genomes with a 1 Mbp context window.

    DNA & Gene
    90Openness
  • Deep-Plant

    1
    Colorado State University +1 otherApril 9, 2026chromatincnnenhancer_prediction+6

    A supervised, chromatin-informed foundation model that predicts regulatory activity directly from plant genomic sequence in Arabidopsis and rice.

    DNA & Gene
    87Openness
  • ChIANet

    Central South UniversityFebruary 25, 20263d_genomechromatinchromatin_contact_prediction+4

    Multimodal deep learning model that predicts protein-mediated chromatin contact maps and loops de novo from protein-binding profiles and sequence across cell types.

    DNA & Gene
    10Openness
  • ARCH3D

    University of MichiganFebruary 25, 20263d_genomechromatincontact_map_reconstruction+5

    A foundation model for global 3D genome architecture that uses masked locus modeling over genome-wide contact profiles to represent chromosome-scale organization.

    DNA & Gene
    19Openness
  • CLM-X

    Hangzhou Institute of Medicine, CASFebruary 18, 2026batch_correctioncell_biologycell_type_annotation+6

    A multimodal single-cell foundation model with a multiway Transformer that jointly models scRNA-seq and scATAC-seq, including RNA-only, ATAC-only, and paired inputs.

    Single-cell
    4Openness
  • ARSENAL

    16
    Stanford UniversityFebruary 6, 2026chromatinlanguage_modelmotif_discovery+6

    A short-context masked DNA language model trained on curated regulatory sequences with a motif-discovery regularizer for zero-shot TF motif recovery and variant effect prediction.

    DNA & Gene
    29Openness
  • GenoME

    Changping Laboratory +1 otherDecember 28, 2025chromatinepigenomicsfoundation_model+8

    A Mixture-of-Experts generative model that turns DNA sequence plus cell-type ATAC-seq into unified epigenomic, transcriptomic, and 3D chromatin profiles, generalizing to unseen cell types.

    DNA & GeneSingle-cell
    8Openness
  • Scooby

    6710
    Technical University of Munich +4 othersOctober 1, 2025chromatinchromatin_accessibility_predictionconvolutional_neural_network+6

    Predicts single-cell-resolution scRNA-seq coverage and scATAC-seq insertion profiles directly from DNA sequence by adapting the Borzoi predictor with a cell-specific decoder.

    Single-cell
    70Openness
  • Broad InstituteAugust 17, 2025chromatinfoundation_modelgene_regulation+7

    Multimodal foundation model predicting genome-wide binding of chromatin-associated proteins from protein sequence, DNA sequence, and cell-type chromatin state.

    DNA & GeneProtein
    25Openness
  • GREmLN

    37
    Chan Zuckerberg Initiative +2 othersJuly 9, 2025cell_type_annotationchromatinfoundation_model+6

    A graph-signal-processing foundation model that embeds gene regulatory network structure directly into its attention mechanism for parameter-efficient single-cell transcriptomics.

    Single-cell
    80Openness
  • AlphaGenome

    1.9K102
    Google DeepMindJune 27, 2025chromatinfoundation_modelgene_expression+4

    Google DeepMind model that predicts thousands of functional genomic tracks at single base-pair resolution from megabase-scale DNA sequences. Open-sourced with public API access in January 2026.

    DNA & Gene
    49Openness
  • MuBind

    271
    Theis LabAugust 8, 2024chromatincnndna+7

    Deep learning model predicting single-cell read counts from DNA sequence features and cell transition graphs to identify transcriptional regulators.

    Single-cell
    59Openness
  • University of TokyoJuly 25, 2024bertchromatinchromatin_state_modeling+7

    BERT-based model pretrained on 15-state ROADMAP chromatin annotations across 127 human cell types to uncover chromatin-state motifs and predict gene expression.

    DNA & Gene
    86Openness
  • Puffin

    10449
    UT Southwestern Medical CenterApril 26, 2024chromatincnngene_expression+3

    Explainable sequence model for transcription initiation that identifies the minimal set of sequence rules governing human promoter activity at base-pair resolution.

    DNA & Gene
    23Openness
  • EpiGePT

    3311
    Tsinghua UniversityJuly 18, 2023chromatinepigenomicsfoundation_model+2

    Transformer model predicting context-specific epigenomic signals across cell types using DNA sequence and transcription factor activity profiles.

    DNA & Gene
    65Openness
  • CellOracle

    463562
    Morris LabFebruary 8, 2023chromatingene_regulatory_network_inferencegraph_neural_network+6

    Machine learning framework for inferring cell-type-specific gene regulatory networks from single-cell multi-omics data and simulating transcription factor perturbations in silico.

    Single-cell
    18Openness
  • Hunan Normal UniversityDecember 14, 2022chromatindeep_learningepigenomic_prediction+4

    Self-attention and densely connected convolutional model for predicting gene expression from histone modifications, with transfer learning for cross-cell-line generalization across 56 REMC cell types.

    DNA & Gene
    22Openness
  • Seoul National UniversityNovember 4, 2022chromatindeep_learningepigenomic_prediction+4

    Transformer-based model for predicting gene expression from histone modifications, incorporating 3D chromatin interaction data and large genomic windows to capture distal regulatory effects.

    DNA & Gene
    71Openness
  • GeneBERT

    27
    Carnegie Mellon UniversityOctober 11, 2021bertchromatinfoundation_model+6

    Multi-modal self-supervised model pre-trained on regulatory genome sequences and transcription factor binding matrices for cell-type-specific regulatory prediction.

    DNA & Gene
    18Openness
  • Basenji2

    473215
    Calico Life SciencesAugust 6, 2020chromatincnngene_expression+5

    Updated Basenji architecture enabling cross-species regulatory sequence activity prediction, trained jointly on human and mouse genomes with improved generalization.

    DNA & Gene
    79Openness
  • Basenji

    473496
    Calico Life SciencesMay 1, 2018chromatincnngene_expression+4

    Deep convolutional neural network that predicts cell-type-specific epigenetic and transcriptional profiles from DNA sequence across large mammalian genomes.

    DNA & Gene
    73Openness
  • University of VirginiaDecember 4, 2017chromatindeep_learningepigenomic_prediction+3

    Attention-based deep learning model that predicts gene expression from histone modification signals across 56 cell types with interpretable attention scores.

    DNA & Gene
    80Openness
  • Basset

    267942
    Harvard UniversityJuly 1, 2016chromatincnngenomics+3

    Deep convolutional neural network that learns the regulatory code of DNA accessibility from DNase-seq data across 164 cell types, enabling variant effect prediction at cis-regulatory elements.

    DNA & Gene
    80Openness