Calico Life Sciences

Deep learning model predicting cell-type-specific RNA-seq coverage at 32 bp resolution from 524 kb of DNA sequence, jointly modeling transcription, splicing, and polyadenylation.

Updated Basenji architecture enabling cross-species regulatory sequence activity prediction, trained jointly on human and mouse genomes with improved generalization.

Deep convolutional neural network that predicts cell-type-specific epigenetic and transcriptional profiles from DNA sequence across large mammalian genomes.