All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 145–168 of 518 filtered models
SpatialFusion
40——Multimodal foundation model integrating spatial transcriptomics, H&E histopathology, and pathway scores for single-cell niche discovery.
Spatial omicsSingle-cellPathology71OpennessStoic
15—155Predicts protein complex stoichiometry from amino acid sequence alone, ranking copy numbers in seconds and exporting AlphaFold3-ready JSON files.
Protein59OpennessSpeciefAI
———Transformer that generates multi-species antibody and nanobody framework regions at the mRNA level, conditioned on input CDRs, across six species.
ProteinRNA46OpennessAetherCell
202—Generative virtual-cell model predicting whole-transcriptome responses to unseen compounds and genetic perturbations, from cell lines to organoids.
Single-cellSmall molecule29OpennessMolecular reasoning model built on DeepSeek-7B, using chain-of-thought and reinforcement learning for property prediction, generation, and reactions.
Small moleculeLanguage model21OpennessCDS-BART
——9Coding-sequence foundation model for mRNA design, pretrained as a BART denoising encoder-decoder on mRNA from nine taxonomic groups.
RNA63OpennessPatchDNA
—2—DNA language model that replaces fixed tokenization with conservation-guided patching, letting models up to 10x smaller match top genomic benchmarks.
DNA & Gene33OpennessCell-centric microscopy foundation model that distills morphology and microenvironment views into a unified embedding for virtual spatial omics.
Spatial omicsImagingPathology15OpennessPaired-sequence protein language model that jointly encodes two interacting chains to predict interactions, binding affinity, and interface contacts.
Protein27OpennessInversePep
———Diffusion generative model for structure-based peptide inverse folding, pairing a geometric GNN encoder with a Transformer denoiser.
Protein10OpennessHitAnno
———Hierarchical language model for atlas-level cell-type annotation of scATAC-seq data that annotates new query datasets without retraining.
Single-cell14OpennessPost-hoc method that restores monotonic scaling to ESM-2 embeddings, yielding Matryoshka-style nested representations for variant effect prediction.
Protein58OpennessBacPT
—1—Bacterial proteome foundation model that learns contextualized gene and whole-genome representations from tens of thousands of complete genomes.
Protein10OpennessEEG-to-text foundation model that turns raw recordings into clinically grounded natural-language narratives instead of fixed-label classifications.
Biosignals18OpennessProtAlign
———Lawrence Livermore National LaboratoryMarch 6, 2026contrastive_learningcross_modal_retrievalembeddings+4Cross-modal protein encoder that aligns ESM-2 sequence embeddings with ProteinMPNN structure embeddings in a shared space for cross-modal retrieval.
Protein35OpennessProtNHF
———Neural Hamiltonian flow for protein sequence generation with inference-time control over composition and net charge via analytical bias potentials.
Protein64OpennessPopformer
———Self-supervised transformer for population genetics, pretrained on 1000 Genomes data, that detects positive selection via haplotype-wise attention.
DNA & Gene19OpennessPerturbGen
25——Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cell trajectories over time.
Single-cell72OpennessSmall-molecule drug discovery foundation model covering ADMET, retrosynthesis, drug-target activity, and molecular optimization in a 2.6B checkpoint.
Small moleculeLanguage model7OpennessD3LM
—142DNA foundation model using masked discrete diffusion to unify bidirectional sequence understanding and de novo generation in one architecture.
DNA & Gene58OpennessMolX
—1—Monash UniversityMarch 1, 2026antibody_drug_conjugate_designbinding_affinity_predictiondrug_discovery+10Graph-transformer foundation model pretrained on 3M protein pockets and 5M molecules as E(3)-equivariant graphs for protein-ligand representation.
Protein11OpennessMultiPUFFIN
———Multimodal foundation model pretrained on ~500K unlabeled PubChem molecules that jointly predicts nine thermophysical properties of small molecules.
Small molecule10Openness