All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 145168 of 518 filtered models

  • MIT +1 otherMarch 16, 2026foundation_modelhistopathologymultimodal+3

    Multimodal foundation model integrating spatial transcriptomics, H&E histopathology, and pathway scores for single-cell niche discovery.

    Spatial omicsSingle-cellPathology
    71Openness
  • Stoic

    15155
    University of BaselMarch 16, 2026graph_neural_networkrepresentation_learningsupervised+1

    Predicts protein complex stoichiometry from amino acid sequence alone, ranking copy numbers in seconds and exporting AlphaFold3-ready JSON files.

    Protein
    59Openness
  • SpeciefAI

    University of EdinburghMarch 16, 2026antibodyantibody_designgenerative+5

    Transformer that generates multi-species antibody and nanobody framework regions at the mRNA level, conditioned on input CDRs, across six species.

    ProteinRNA
    46Openness
  • Sun Yat-sen UniversityMarch 13, 2026drug_repurposingfoundation_modelgenerative+6

    Generative virtual-cell model predicting whole-transcriptome responses to unseen compounds and genetic perturbations, from cell lines to organoids.

    Single-cellSmall molecule
    29Openness
  • Pengcheng Laboratory +2 othersMarch 13, 2026chain_of_thoughtcheminformaticsdrug_discovery+6

    Molecular reasoning model built on DeepSeek-7B, using chain-of-thought and reinforcement learning for property prediction, generation, and reactions.

    Small moleculeLanguage model
    21Openness
  • CDS-BART

    9
    MOGAM Institute for Biomedical ResearchMarch 12, 2026bartfoundation_modelgene_expression+5

    Coding-sequence foundation model for mRNA design, pretrained as a BART denoising encoder-decoder on mRNA from nine taxonomic groups.

    RNA
    63Openness
  • EvoFlows

    2
    CradleMarch 12, 2026antibodyflow_matchinggenerative+5

    Edit-based flow-matching model that proposes protein variants by learning insertions, deletions, and substitutions on a template sequence.

    Protein
    21Openness
  • PatchDNA

    2
    Relation TherapeuticsMarch 12, 2026dnafoundation_modelgenomics+4

    DNA language model that replaces fixed tokenization with conservation-guided patching, letting models up to 10x smaller match top genomic benchmarks.

    DNA & Gene
    33Openness
  • MIT +1 otherMarch 11, 2026cell_type_annotationfoundation_modelgene_expression_prediction+7

    Cell-centric microscopy foundation model that distills morphology and microenvironment views into a unified embedding for virtual spatial omics.

    Spatial omicsImagingPathology
    15Openness
  • National University of SingaporeMarch 10, 2026antibodybinding_affinity_predictionfoundation_model+6

    Paired-sequence protein language model that jointly encodes two interacting chains to predict interactions, binding affinity, and interface contacts.

    Protein
    27Openness
  • InversePep

    Keshav Memorial Engineering CollegeMarch 10, 2026diffusiongenerativegraph_neural_network+4

    Diffusion generative model for structure-based peptide inverse folding, pairing a geometric GNN encoder with a Transformer denoiser.

    Protein
    10Openness
  • HitAnno

    Tsinghua UniversityMarch 10, 2026cell_type_annotationchromatin_accessibilitylanguage_model+4

    Hierarchical language model for atlas-level cell-type annotation of scATAC-seq data that annotates new query datasets without retraining.

    Single-cell
    14Openness
  • Duke UniversityMarch 8, 2026embeddingsknowledge_distillationproteomics+3

    Post-hoc method that restores monotonic scaling to ESM-2 embeddings, yielding Matryoshka-style nested representations for variant effect prediction.

    Protein
    58Openness
  • BacPT

    1
    University of FloridaMarch 7, 2026bacterial_genomicsenzyme_annotationfoundation_model+6

    Bacterial proteome foundation model that learns contextualized gene and whole-genome representations from tens of thousands of complete genomes.

    Protein
    10Openness
  • NeuroNarrator

    Stevens Institute of TechnologyMarch 7, 2026clinical_narrative_generationcontrastive_learningeeg+6

    EEG-to-text foundation model that turns raw recordings into clinically grounded natural-language narratives instead of fixed-label classifications.

    Biosignals
    18Openness
  • ProtAlign

    Lawrence Livermore National LaboratoryMarch 6, 2026contrastive_learningcross_modal_retrievalembeddings+4

    Cross-modal protein encoder that aligns ESM-2 sequence embeddings with ProteinMPNN structure embeddings in a shared space for cross-modal retrieval.

    Protein
    35Openness
  • ProtNHF

    Oak Ridge National LaboratoryMarch 6, 2026de_novo_designflow_matchinggenerative+4

    Neural Hamiltonian flow for protein sequence generation with inference-time control over composition and net charge via analytical bias potentials.

    Protein
    64Openness
  • Popformer

    University of PennsylvaniaMarch 6, 2026foundation_modelgenomicspopulation_genetics+6

    Self-supervised transformer for population genetics, pretrained on 1000 Genomes data, that detects positive selection via haplotype-wise attention.

    DNA & Gene
    19Openness
  • PerturbGen

    25
    Wellcome Sanger InstituteMarch 5, 2026cell_biologyfoundation_modelgene_expression+6

    Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cell trajectories over time.

    Single-cell
    72Openness
  • Liquid AI +1 otherMarch 3, 2026admet_predictiondrug_discoverydrug_target_activity_prediction+6

    Small-molecule drug discovery foundation model covering ADMET, retrosynthesis, drug-target activity, and molecular optimization in a 2.6B checkpoint.

    Small moleculeLanguage model
    7Openness
  • D3LM

    142
    Renmin University of ChinaMarch 2, 2026diffusiondnafoundation_model+6

    DNA foundation model using masked discrete diffusion to unify bidirectional sequence understanding and de novo generation in one architecture.

    DNA & Gene
    58Openness
  • FlashPPI

    40140.8K
    Tatta BioMarch 1, 2026contrastive_learninginteraction_network_inferencemetagenomics+4

    Contrastive model built on a genomic language model that predicts physical protein-protein interactions across a microbial proteome in linear time.

    Protein
    14Openness
  • MolX

    1
    Monash UniversityMarch 1, 2026antibody_drug_conjugate_designbinding_affinity_predictiondrug_discovery+10

    Graph-transformer foundation model pretrained on 3M protein pockets and 5M molecules as E(3)-equivariant graphs for protein-ligand representation.

    Protein
    11Openness
  • MultiPUFFIN

    NTNU +2 othersMarch 1, 2026drug_discoveryfoundation_modelgraph_neural_network+6

    Multimodal foundation model pretrained on ~500K unlabeled PubChem molecules that jointly predicts nine thermophysical properties of small molecules.

    Small molecule
    10Openness