All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 121–144 of 316 filtered models
Eva
—4—Enable Medicine +4 othersDecember 12, 2025cell_type_annotationcross_modal_inferencefoundation_model+8Tissue imaging foundation model pretrained on matched H&E histology and spatial proteomics for cross-modal inference and zero-shot retrieval.
PathologySpatial omics4OpennessProteinEBM
—7—Energy-based model of protein conformational space, turning a diffusion model into a statistical potential for structure ranking and mutation scoring.
Protein8OpennessPlantBiMoE
8—6Plant genome foundation model pairing a bidirectional Mamba backbone with sparse Mixture-of-Experts, pretrained on 25.4B nucleotides from 42 species.
DNA & Gene53OpennessPanFoMa
2——Pan-cancer single-cell foundation model with a hybrid Transformer-Mamba architecture, released with the PanFoMaBench cancer evaluation benchmark.
Single-cell13OpennessISTS
———Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.
Single-cellDNA & Gene20OpennessCLEF
554—Single-lead ECG foundation model pretrained on 12-lead recordings, weighting contrastive pairs by clinical risk for cardiovascular risk prediction.
Biosignals62OpennessgRNAde
310321MRC Laboratory of Molecular Biology +1 otherDecember 1, 2025de_novo_designgenerativegraph_neural_network+5RNA inverse-folding model that generates sequences predicted to fold into a target 3D backbone, capturing non-canonical pairs and tertiary motifs.
RNA98OpennessPULSAR
364166Hierarchical single-cell foundation model that turns scRNA-seq profiles into zero-shot donor-level embeddings for disease and biomarker prediction.
Single-cellProtein58OpennessFusionProt
183—Technion – Israel Institute of Technology +1 otherNovember 26, 2025function_predictiongraph_neural_networkmultimodal+4Multimodal protein representation model that iteratively fuses a sequence language model with a 3D structure encoder through a shared learnable token.
Protein68OpennesseccDNAMamba
5——Bidirectional state-space (Mamba-2) genomic model for ultra-long extrachromosomal circular DNA, scaling linearly with sequence length.
DNA & Gene54OpennessMIMYR
—2—Generative framework that reconstructs missing spatial transcriptomics regions by jointly predicting cell locations, cell types, and gene expression.
Spatial omicsSingle-cell16OpennessNeuroVFM
554654University of Michigan +1 otherNovember 23, 2025ctfoundation_modeljoint_embedding_predictive_architecture+8Generalist neuroimaging vision foundation model pretrained on 5.24M clinical MRI and CT volumes for radiologic diagnosis and report generation.
Imaging57OpennessMethylAI
7——Cross-species-pretrained CNN that predicts single-CpG DNA methylation from genomic sequence and interprets the cis-regulatory motifs that govern it.
DNA & Gene64OpennessSIGMMA
—1—Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.
PathologySpatial omics20OpennessMergeDNA
—5—Hierarchical DNA foundation model that co-trains a dynamic token-merging tokenizer with latent Transformers to match genomic information density.
DNA & Gene5OpennessCryoSiam
201—European Molecular Biology LaboratoryNovember 12, 2025convolutional_neural_networkcryo_etdenoising+8Self-supervised Siamese network for cryo-electron tomography, enabling zero-shot denoising, segmentation, and macromolecule detection in tomograms.
Imaging64OpennessJWTH
—1—Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.
Pathology5OpennessAtacformer
28297Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.
Single-cellDNA & Gene32OpennessscLDM
587—Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.
Single-cell75OpennessH3BERTa
1—201Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.
ProteinLanguage model83OpennessGPFM
12954—Hong Kong University of Science and Technology +3 othersNovember 1, 2025cancer_diagnosisfeature_extractionfoundation_model+8Histopathology foundation model extracting general-purpose features from H&E patches by distilling the UNI, Phikon, and CONCH pathology encoders.
Pathology84Openness