All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 121144 of 316 filtered models

  • Eva

    4
    Enable Medicine +4 othersDecember 12, 2025cell_type_annotationcross_modal_inferencefoundation_model+8

    Tissue imaging foundation model pretrained on matched H&E histology and spatial proteomics for cross-modal inference and zero-shot retrieval.

    PathologySpatial omics
    4Openness
  • ProteinEBM

    7
    MITDecember 9, 2025conformational_dynamicsconformational_samplingdiffusion+5

    Energy-based model of protein conformational space, turning a diffusion model into a statistical potential for structure ranking and mutation scoring.

    Protein
    8Openness
  • Huazhong University of Science and TechnologyDecember 8, 2025dnafoundation_modelgene_expression+6

    Plant genome foundation model pairing a bidirectional Mamba backbone with sparse Mixture-of-Experts, pretrained on 25.4B nucleotides from 42 species.

    DNA & Gene
    53Openness
  • PanFoMa

    2
    Shanghai Jiao Tong University +4 othersDecember 2, 2025batch_correctioncancercell_type_annotation+7

    Pan-cancer single-cell foundation model with a hybrid Transformer-Mamba architecture, released with the PanFoMaBench cancer evaluation benchmark.

    Single-cell
    13Openness
  • ISTS

    New York UniversityDecember 2, 2025autoencoderbertcancer_classification+9

    Pan-cancer multi-omic foundation model encoding CpG-island DNA methylation and RNA-seq for zero-shot cancer classification and mutation prediction.

    Single-cellDNA & Gene
    20Openness
  • CLEF

    554
    Nokia Bell LabsDecember 1, 2025cardiovascular_risk_predictioncnncontrastive_learning+5

    Single-lead ECG foundation model pretrained on 12-lead recordings, weighting contrastive pairs by clinical risk for cardiovascular risk prediction.

    Biosignals
    62Openness
  • gRNAde

    310321
    MRC Laboratory of Molecular Biology +1 otherDecember 1, 2025de_novo_designgenerativegraph_neural_network+5

    RNA inverse-folding model that generates sequences predicted to fold into a target 3D backbone, capturing non-canonical pairs and tertiary motifs.

    RNA
    98Openness
  • PULSAR

    364166
    Stanford UniversityNovember 26, 2025biomarker_predictiondisease_classificationfoundation_model+6

    Hierarchical single-cell foundation model that turns scRNA-seq profiles into zero-shot donor-level embeddings for disease and biomarker prediction.

    Single-cellProtein
    58Openness
  • Technion – Israel Institute of Technology +1 otherNovember 26, 2025function_predictiongraph_neural_networkmultimodal+4

    Multimodal protein representation model that iteratively fuses a sequence language model with a 3D structure encoder through a shared learnable token.

    Protein
    68Openness
  • Brown UniversityNovember 25, 2025dnafoundation_modelgenomics+5

    Bidirectional state-space (Mamba-2) genomic model for ultra-long extrachromosomal circular DNA, scaling linearly with sequence length.

    DNA & Gene
    54Openness
  • MIMYR

    2
    Carnegie Mellon UniversityNovember 24, 2025cell_biologycell_type_annotationdata_imputation+6

    Generative framework that reconstructs missing spatial transcriptomics regions by jointly predicting cell locations, cell types, and gene expression.

    Spatial omicsSingle-cell
    16Openness
  • NeuroVFM

    554654
    University of Michigan +1 otherNovember 23, 2025ctfoundation_modeljoint_embedding_predictive_architecture+8

    Generalist neuroimaging vision foundation model pretrained on 5.24M clinical MRI and CT volumes for radiologic diagnosis and report generation.

    Imaging
    57Openness
  • MethylAI

    7
    Guangzhou National LaboratoryNovember 20, 2025cnndnaepigenetics+6

    Cross-species-pretrained CNN that predicts single-CpG DNA methylation from genomic sequence and interprets the cis-regulatory motifs that govern it.

    DNA & Gene
    64Openness
  • SIGMMA

    1
    Helmholtz Munich +1 otherNovember 19, 2025contrastive_learningcross_modal_retrievalgene_expression_prediction+7

    Multi-modal contrastive model that aligns H&E histopathology with spatial transcriptomics across tissue scales to predict gene expression from images.

    PathologySpatial omics
    20Openness
  • MergeDNA

    5
    Westlake University +1 otherNovember 17, 2025foundation_modelgenomicsmulti_omics+6

    Hierarchical DNA foundation model that co-trains a dynamic token-merging tokenizer with latent Transformers to match genomic information density.

    DNA & Gene
    5Openness
  • E1

    1131115.5K
    ProfluentNovember 13, 2025contact_predictionfoundation_modelproteomics+6

    Retrieval-augmented protein encoders that fuse homologous sequences into a single-pass transformer for variant effect and contact prediction.

    Protein
    47Openness
  • CryoSiam

    201
    European Molecular Biology LaboratoryNovember 12, 2025convolutional_neural_networkcryo_etdenoising+8

    Self-supervised Siamese network for cryo-electron tomography, enabling zero-shot denoising, segmentation, and macromolecule detection in tomograms.

    Imaging
    64Openness
  • JWTH

    1
    Technical University of MunichNovember 7, 2025biomarker_detectioncancerfoundation_model+4

    Pathology foundation model that fuses global patch and cell-level tokens via joint-weighted attention pooling for H&E-based biomarker detection.

    Pathology
    5Openness
  • Nona

    3
    GenentechNovember 6, 2025discrete_diffusionfoundation_modelfunctional_genomics+8

    Genomics foundation model that unifies sequence-to-function prediction, DNA language modeling, and generative regulatory design in one backbone.

    DNA & GeneRNA
    8Openness
  • University of VirginiaNovember 4, 2025batch_correctioncell_type_annotationchromatin+7

    Transformer foundation model for single-cell ATAC-seq that embeds both cells and cis-regulatory elements for annotation and batch correction.

    Single-cellDNA & Gene
    32Openness
  • scLDM

    587
    Chan Zuckerberg InitiativeNovember 4, 2025autoencodercell_biologydata_augmentation+8

    Latent diffusion model for generating single-cell gene expression profiles, pairing a permutation-invariant autoencoder with a diffusion transformer.

    Single-cell
    75Openness
  • PLUTO-4

    2
    PathAINovember 4, 2025digital_pathologyfoundation_modelhistology+6

    Digital pathology foundation models from PathAI, spanning a 22M-parameter variant and a 1.1B-parameter flagship trained on 551K whole-slide images.

    Pathology
    19Openness
  • H3BERTa

    1201
    University of BernNovember 3, 2025antibodyantibody_repertoire_analysisbert+8

    Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.

    ProteinLanguage model
    83Openness
  • GPFM

    12954
    Hong Kong University of Science and Technology +3 othersNovember 1, 2025cancer_diagnosisfeature_extractionfoundation_model+8

    Histopathology foundation model extracting general-purpose features from H&E patches by distilling the UNI, Phikon, and CONCH pathology encoders.

    Pathology
    84Openness