All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 121144 of 552 filtered models

  • ATOMICA

    3
    Harvard UniversityMarch 16, 2026binding_site_predictionfoundation_modelgraph_neural_network+6

    Geometric deep learning model that learns atomic-scale representations of molecular interfaces across proteins, small molecules, and nucleic acids.

    ProteinSmall moleculeRNA
    88Openness
  • MIT +1 otherMarch 16, 2026foundation_modelhistopathologymultimodal+3

    Multimodal foundation model integrating spatial transcriptomics, H&E histopathology, and pathway scores for single-cell niche discovery.

    Spatial omicsSingle-cellPathology
    71Openness
  • AnewOmni

    842
    Tsinghua University +1 otherMarch 15, 2026antibodyde_novo_designdiffusion+6

    All-atom generative foundation model that designs small molecules, peptides, and nanobodies against a target binding site from a single checkpoint.

    ProteinSmall molecule
    63Openness
  • Sun Yat-sen UniversityMarch 13, 2026drug_repurposingfoundation_modelgenerative+6

    Generative virtual-cell model predicting whole-transcriptome responses to unseen compounds and genetic perturbations, from cell lines to organoids.

    Single-cellSmall molecule
    29Openness
  • CDS-BART

    9
    MOGAM Institute for Biomedical ResearchMarch 12, 2026bartfoundation_modelgene_expression+5

    Coding-sequence foundation model for mRNA design, pretrained as a BART denoising encoder-decoder on mRNA from nine taxonomic groups.

    RNA
    63Openness
  • mnDINO

    Morgridge Institute for ResearchMarch 12, 2026cell_biologyfluorescence_microscopyfoundation_model+4

    Vision transformer trained with DINO self-supervision to segment micronuclei in DNA-stained fluorescence images across cell lines and microscopes.

    Imaging
    32Openness
  • PatchDNA

    2
    Relation TherapeuticsMarch 12, 2026dnafoundation_modelgenomics+4

    DNA language model that replaces fixed tokenization with conservation-guided patching, letting models up to 10x smaller match top genomic benchmarks.

    DNA & Gene
    33Openness
  • MIT +1 otherMarch 11, 2026cell_type_annotationfoundation_modelgene_expression_prediction+7

    Cell-centric microscopy foundation model that distills morphology and microenvironment views into a unified embedding for virtual spatial omics.

    Spatial omicsImagingPathology
    15Openness
  • National University of SingaporeMarch 10, 2026antibodybinding_affinity_predictionfoundation_model+6

    Paired-sequence protein language model that jointly encodes two interacting chains to predict interactions, binding affinity, and interface contacts.

    Protein
    27Openness
  • FishMamba-1

    11
    Institute of Hydrobiology, Chinese Academy of SciencesMarch 9, 2026dnafoundation_modelgenome_annotation+4

    Genomic foundation model for Cypriniformes fish, built on a Mamba-2 state space model with a 32 kb context window for long-range genome modeling.

    DNA & Gene
    50Openness
  • BacPT

    1
    University of FloridaMarch 7, 2026bacterial_genomicsenzyme_annotationfoundation_model+6

    Bacterial proteome foundation model that learns contextualized gene and whole-genome representations from tens of thousands of complete genomes.

    Protein
    10Openness
  • NeuroNarrator

    Stevens Institute of TechnologyMarch 7, 2026clinical_narrative_generationcontrastive_learningeeg+6

    EEG-to-text foundation model that turns raw recordings into clinically grounded natural-language narratives instead of fixed-label classifications.

    Biosignals
    18Openness
  • Popformer

    University of PennsylvaniaMarch 6, 2026foundation_modelgenomicspopulation_genetics+6

    Self-supervised transformer for population genetics, pretrained on 1000 Genomes data, that detects positive selection via haplotype-wise attention.

    DNA & Gene
    19Openness
  • PerturbGen

    25
    Wellcome Sanger InstituteMarch 5, 2026cell_biologyfoundation_modelgene_expression+6

    Generative single-cell foundation model trained on 100M+ transcriptomes that predicts how genetic perturbations reshape cell trajectories over time.

    Single-cell
    72Openness
  • Liquid AI +1 otherMarch 3, 2026admet_predictiondrug_discoverydrug_target_activity_prediction+6

    Small-molecule drug discovery foundation model covering ADMET, retrosynthesis, drug-target activity, and molecular optimization in a 2.6B checkpoint.

    Small moleculeLanguage model
    7Openness
  • D3LM

    142
    Renmin University of ChinaMarch 2, 2026diffusiondnafoundation_model+6

    DNA foundation model using masked discrete diffusion to unify bidirectional sequence understanding and de novo generation in one architecture.

    DNA & Gene
    58Openness
  • MolX

    1
    Monash UniversityMarch 1, 2026antibody_drug_conjugate_designbinding_affinity_predictiondrug_discovery+10

    Graph-transformer foundation model pretrained on 3M protein pockets and 5M molecules as E(3)-equivariant graphs for protein-ligand representation.

    Protein
    11Openness
  • MultiPUFFIN

    NTNU +2 othersMarch 1, 2026drug_discoveryfoundation_modelgraph_neural_network+6

    Multimodal foundation model pretrained on ~500K unlabeled PubChem molecules that jointly predicts nine thermophysical properties of small molecules.

    Small molecule
    10Openness
  • VirtualCRISPR

    Chan Zuckerberg Biohub Chicago +2 othersFebruary 28, 2026crisprdrug_discoveryfoundation_model+2

    Large language model trained on functional genomics data to prioritize novel therapeutic targets from genome-wide CRISPR knockout screens.

    DNA & GeneLanguage model
    12Openness
  • ARCH3D

    University of MichiganFebruary 25, 20263d_genomechromatincontact_map_reconstruction+5

    Foundation model for 3D genome architecture, using masked locus modeling over genome-wide contact profiles to capture chromosome-scale organization.

    DNA & Gene
    19Openness
  • BOTANIC-0

    1177
    Living ModelsFebruary 23, 2026dnafoundation_modelgene_expression+5

    Plant genomic foundation models from 0.1B to 1B parameters, pretrained on 43 phylogenetically diverse plant genomes for variant effect prediction.

    DNA & Gene
    19Openness
  • Vanderbilt University Medical CenterFebruary 23, 2026drug_discoveryfoundation_modelgraph_neural_network+4

    Knowledge-graph foundation model for drug repurposing, grounding a biomedical graph in cell-type-specific genetic associations to rank indications.

    Single-cellSmall molecule
    11Openness
  • MACE-POLAR-1

    16
    University of CambridgeFebruary 23, 2026drug_discoveryequivariant_neural_networkfoundation_model+5

    Polarizable machine-learning interatomic potential extending MACE with long-range electrostatics, trained on 100M OMol25 DFT calculations.

    Small moleculeProtein
    19Openness
  • University of BristolFebruary 19, 2026data_generationdiffusionfoundation_model+4

    Single-cell foundation model applying discrete diffusion directly to scRNA-seq counts, generating unconditional and perturbation-conditioned profiles.

    Single-cell
    10Openness