All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 552 filtered models
LEAF-1
———Genomics foundation model that represents individual DNA fragments in a learned semantic space for cell-free DNA cancer detection and cell typing.
DNA & GeneSingle-cell4OpennessIgGM2
———All-atom foundation model for immune-receptor design that predicts structures and co-designs CDR sequences for antibodies, nanobodies, and TCRs.
Protein32OpennessStructure-based drug design language model fusing protein structural and evolutionary encoders with SAFE fragment tokens for hit-to-lead generation.
Small moleculeProtein10OpennessWattmaMod
———RNA modification profiling from nanopore direct RNA-seq signal; self-supervised pretraining resolves 11 modification types and extends to new ones.
RNABiosignals21OpennessGAZE
———Physics-informed graph neural network predicting metabolite concentrations from gene expression, generalizing zero-shot to unseen metabolites.
MetabolomicsSmall moleculeDNA & Gene19OpennessScaleSurfer
8——Brain MRI morphometry model that estimates cortical thickness, surface area, and volume in milliseconds instead of hours.
Imaging47OpennessCryoACE
———Atomic protein model building from cryo-EM density maps, resolving conformational heterogeneity through atom-centric sampling and diffusion.
ProteinImaging38OpennessZAO
———Molecular foundation model that turns SMILES into 2048-dimensional embeddings from multiple 3D conformations for ADMET and virtual screening.
Small molecule16OpennessPlantGeneAnn
12—126Plant genome foundation model for ab initio gene structure annotation, predicting genes, coding sequences, and exons at single-nucleotide resolution.
DNA & Gene66OpennessMolexar
7—28Multimodal molecular generation model for drug design, conditioned on properties, pharmacophores, protein sequences, or protein binding pockets.
Small moleculeProtein82OpennessEventHorizon
———ARUP Laboratories +1 otherJune 22, 2026cell_type_annotationdiagnostic_classificationflow_cytometry+6Self-supervised foundation model for clinical flow cytometry, producing panel-agnostic specimen-level representations from multi-panel data.
BiosignalsSingle-cell4OpennessBioMatrix
41—161Decoder-only foundation model that unifies sequences, 3D structures, and natural language for small molecules and proteins in one shared token space.
ProteinSmall moleculeLanguage model67OpennessUltraNMR
11—Hong Kong University of Science and Technology +4 othersJune 18, 2026foundation_modelself_supervisedtransfer_learning+1NMR foundation model trained on 158 million simulated 1H and 13C spectra, transferring simulation-learned representations to real experimental data.
Small moleculeMetabolomics43OpennessBoltzMol-1
4.1K——Small-molecule hit-discovery pipeline using Boltz-2 co-folding and affinity prediction to rank in-stock compounds or make-on-demand chemical space.
Small moleculeProtein7OpennessBoltzProt-1
4.1K——De novo protein binder and nanobody design pipeline that ranks candidates by a protein-protein interaction model rather than structural confidence.
Protein11OpennessvBx-1.0
———Multimodal foundation model for precision neurology that reconstructs a patient's molecular brain state from blood to predict disease progression.
Single-cellDNA & Gene5OpennessTox21mer
———National Institute of Environmental Health SciencesJune 15, 2026embeddingsfoundation_modelrepresentation_learning+2Toxicity screening foundation model that encodes Tox21 concentration-response curves and assay metadata into reusable 768-dimensional embeddings.
Small moleculeBiosignals23OpennessOmnii
———Genomic language model from Radical Numerics with a 2 Mbp context window, built for zero-shot variant effect prediction and sequence design.
DNA & Gene5OpennessTCRDiff
7——Conditional denoising diffusion model that designs antigen-specific TCR CDR3β sequences conditioned on peptide-MHC targets and germline V-genes.
Protein75Openness