All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 1–24 of 440 filtered models
MethylSeqNet
———University of California, Berkeley +1 otherJune 7, 2026chromatin_accessibility_predictiondna_methylationepigenetics+6Conditions a pretrained DNA sequence embedding on CpG methylation to predict gene regulation across cell types and alleles, generalizing zero-shot to imprinting, X-inactivation, and accessibility.
DNA & Gene18OpennessDaX
1——Pathology vision foundation model adapting DINOv3-style self-supervised learning to whole-slide histopathology across continuous magnifications and scales.
Pathology11Opennessdrug-SFM
———Specificity Foundation Model that predicts small-molecule drug-target protein specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.
Small molecule16Opennessmir-SFM
———Specificity Foundation Model that predicts microRNA-mRNA target specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.
RNA25Opennesstf-SFM
———Specificity Foundation Model that predicts transcription factor-DNA binding specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.
DNA & Gene18Opennessenzyme-SFM
———Specificity Foundation Model that predicts enzyme-substrate specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.
Protein23OpennessFlashABB
8——Oxford Protein Informatics Group (OPIG)June 4, 2026antibodydevelopability_predictionfoundation_model+4Pretrained antibody structure predictor that outputs full paired heavy/light 3D structures faster than protein language models generate embeddings.
Protein54OpennesscrisprSFM
———Specificity Foundation Model that predicts CRISPR gRNA off-target DNA specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.
DNA & Gene19OpennessmhcSFM
———Specificity Foundation Model that predicts peptide-MHC binding specificity from sequence using a physics-derived dual-encoder with symmetric contrastive learning.
Protein23OpennessLDARNet
—1—A 120M-parameter genomic foundation model that learns adaptive DNA token boundaries via H-Net-style dynamic chunking instead of fixed k-mer or byte-pair tokenization.
DNA & Gene26OpennessSQUALL
———Multimodal foundation model pretrained on 1.76 billion paired histology-spatial transcriptomics spots, linking whole-slide images to spatial molecular programs.
PathologySpatial omics6OpennessBrainGFM
173—A graph foundation model for fMRI brain networks, pretrained across 27 datasets with graph and language prompts for zero/few-shot generalization to unseen disorders.
Biosignals16OpennessCryoProt
———Protein pretraining framework that learns representations directly from cryo-EM density maps, transferring to flexibility, active-site, binding-affinity, and stability tasks.
ImagingProtein11OpennessTESSERA
5——Self-supervised foundation model that learns reusable representations of cancer genomes from somatic SNVs and copy-number alterations across 33 tumor types.
DNA & Gene28OpennessVermeer
1——Channel-adaptive autoregressive generative model that synthesizes in-silico fluorescence microscopy of protein subcellular localization from amino-acid sequence and cellular landmark stains.
ImagingProtein17OpennessmRNAutilus
—1—A masked discrete-diffusion model over millions of full-length mRNAs, guided by Monte Carlo Tree Search for joint codon optimization and de novo UTR design.
RNA7OpennessTxFM
2——A self-supervised masked autoencoder for RNA-seq count data, pretrained on 1.4M public samples to learn transferable transcriptomic representations without per-dataset re-training.
Single-cell12OpennessAMix-2
———A protein-text foundation model embedding sequences and natural language in a shared token space, enabling protein understanding and de novo design from one checkpoint.
ProteinLanguage model10OpennessSciCore-Omics
8—230A tri-modal foundation model unifying histology images, spatial transcriptomics, and biological language for zero-shot spatial biology and pathology reasoning.
PathologySpatial omics65OpennessPIGMENT
———A physics-informed generative foundation model for quantitative diffusion MRI that maps brain microstructure (tensor, kurtosis, NODDI) and adapts zero-shot to each participant's data.
Imaging11OpennessGlucoFM
———Google Research +1 otherMay 29, 2026continuous_glucose_monitoringfoundation_modelglucose_forecasting+4A dual-stream self-supervised foundation model for continuous glucose monitoring data, separating slow physiological state from transient glucose events.
Biosignals11OpennessDanioDecima
———A zebrafish DNA sequence-to-function model predicting cell-type-specific single-cell expression across 85 cell-type x developmental-timepoint combinations during embryogenesis.
DNA & GeneSingle-cell22OpennessGenBloom
3——Genetically aligned foundation model for blood smear cytology that links single white-blood-cell morphology to chromosomal aberrations and mutations for AML/APL diagnosis.
Pathology65Openness