All Competitors

Every biological foundation model, evaluated and ranked by the bio.rodeo team

Showing 97120 of 158 filtered models

  • New York UniversityNovember 10, 2025cnndrug_discoverygraph_neural_network+8

    Multimodal conversational LLM for metabolite analysis, fusing a molecular-graph GNN and molecular-image CNN with a Vicuna-13B language backbone.

    MetabolomicsSmall molecule
    48Openness
  • TEMPO

    5
    Chinese University of Hong Kong, Shenzhen +1 otherNovember 7, 2025autoregressiveconformational_ensemble_generationgenerative+4

    Protein dynamics model that samples conformational ensembles autoregressively at slow and fast timescales, generalizing zero-shot to unseen proteins.

    Protein
    25Openness
  • H3BERTa

    1201
    University of BernNovember 3, 2025antibodyantibody_repertoire_analysisbert+8

    Antibody language model pretrained only on CDR-H3 loops, giving embeddings for immune repertoire analysis and antibody sequence classification.

    ProteinLanguage model
    83Openness
  • Boston UniversityOctober 31, 2025antibodybinding_affinity_predictionlanguage_model+4

    Paired heavy/light antibody language model fine-tuning ESM-2 and ESM-C with CDR-preferential masking for zero-shot binding affinity embeddings.

    Protein
    8Openness
  • Verily Life SciencesOctober 24, 2025cross_attentiondisease_risk_predictionelectronic_health_records+7

    Multimodal EHR foundation model that fuses polygenic risk scores into a GPT-2-style backbone by cross-attention for zero-shot disease risk prediction.

    Language modelDNA & Gene
    8Openness
  • EvoIF

    Zhejiang University +1 otherOctober 8, 2025graph_neural_networkprotein_evolutionprotein_fitness_prediction+4

    Compact protein fitness predictor that fuses within-family evolutionary profiles with inverse-folding logits for zero-shot variant effect prediction.

    Protein
    26Openness
  • Stockholm UniversityOctober 3, 2025de_novo_designgenerativepeptides+5

    GPCR structure prediction and peptide design model that generates linear and cyclic peptide agonists carrying noncanonical amino acids, zero-shot.

    Protein
    58Openness
  • FLOWR.root

    1383
    Pfizer +3 othersOctober 2, 2025binding_affinity_predictionde_novo_designflow_matching+4

    SE(3)-equivariant flow-matching model for pocket-aware 3D ligand generation, predicting binding affinity and confidence in the same network.

    Small moleculeProtein
    87Openness
  • University of PennsylvaniaOctober 1, 2025batch_integrationcell_type_annotationfoundation_model+5

    Kidney-specialized single-cell foundation model trained across four mammalian species for zero-shot cell-type annotation and batch integration.

    Single-cellSpatial omics
    22Openness
  • BioVERSE

    2
    IBM ResearchOctober 1, 2025cell_biologycell_type_annotationcross_modal_question_answering+5

    Multimodal biomedical framework aligning frozen single-cell and protein model encoders to an LLM's embedding space for zero-shot reasoning.

    Language modelSingle-cellProtein
    23Openness
  • scYeast

    51
    Shanghai Jiao Tong UniversityAugust 20, 2025cell_type_annotationfoundation_modeltransformer+1

    Single-cell foundation model for yeast that injects regulatory network priors into transformer attention for zero-shot and fine-tuned analysis.

    Single-cell
    68Openness
  • Broad InstituteAugust 17, 2025chromatinfoundation_modelgene_regulation+7

    Multimodal foundation model predicting genome-wide binding of chromatin-associated proteins from protein sequence, DNA sequence, and chromatin state.

    DNA & GeneProtein
    25Openness
  • Central South UniversityAugust 11, 2025foundation_modelgene_expression_predictionhistology+6

    Histology vision transformer with 80M parameters that predicts spatial gene expression from H&E tissue images and transfers to tumor detection.

    PathologySpatial omics
    59Openness
  • CLASP

    44
    McGill UniversityAugust 10, 2025contrastive_learningcross_modal_retrievalgraph_neural_network+7

    Tri-modal contrastive model aligning protein structure, sequence, and text in a shared space for zero-shot cross-modal retrieval and classification.

    Protein
    42Openness
  • University of Science and Technology of ChinaAugust 7, 2025bertfoundation_modellanguage_model+8

    RNA foundation model pretrained jointly on sequences and secondary structures for structure prediction, homology and splice site classification.

    RNA
    92Openness
  • EPFLAugust 1, 2025foundation_modelgene_essentiality_predictionprotein_protein_interaction_prediction+4

    Proteome-scale protein language model whose representations enable zero-shot protein-protein interaction and gene essentiality prediction.

    Protein
    64Openness
  • Meta AIJuly 23, 2025cnnconformerelectromyography+7

    Surface-EMG wristband models that decode hand gestures, handwriting, and wrist movement, generalizing across users without per-person calibration.

    Biosignals
    13Openness
  • Chai-2

    58
    Chai DiscoveryJuly 5, 2025antibodyantibody_designde_novo_design+3

    Multimodal all-atom generative model for zero-shot de novo antibody and protein-binder design, validated by wet-lab hit rates from small batches.

    Protein
    7Openness
  • SensorLM

    58
    Google Research +2 othersJune 10, 2025activity_recognitioncontrastive_learningcross_modal_retrieval+6

    Sensor-language foundation models aligning wearable biosignals with text for zero-shot activity recognition, retrieval, and sensor captioning.

    BiosignalsLanguage model
    41Openness
  • BioCLIP 2

    774348.7K
    Imageomics InstituteMay 29, 2025biodiversitycontrastive_learningfoundation_model+6

    Vision foundation model for the tree of life, trained on 214 million organism images across 952,000 taxa for zero-shot species classification.

    Imaging
    93Openness
  • Chan Zuckerberg InitiativeApril 29, 2025cell_type_annotationcross_speciesdisease_prediction+6

    Generative single-cell foundation model trained on 112 million cells from 12 species, autoregressively modeling gene identities and expression counts.

    Single-cell
    67Openness
  • Swin-BOB

    504
    University of OxfordApril 9, 2025foundation_modelmrisegmentation+3

    3D MRI organ segmentation foundation model built on Swin-UNETR and trained on the UKBOB whole-body dataset covering 72 organs and skeletal structures.

    Imaging
    64Openness
  • Guangzhou Medical University +1 otherFebruary 23, 2025cell_type_annotationcross_attentiondna_methylation+5

    Single-cell DNA methylation foundation model capturing genome-wide CpG dependencies in whole-genome bisulfite sequencing across tissues and species.

    Single-cellDNA & Gene
    78Openness
  • FetalCLIP

    7022
    Mohamed bin Zayed University of Artificial Intelligence +1 otherFebruary 20, 2025classificationcontrastive_learningfoundation_model+7

    Vision-language foundation model for fetal ultrasound, pretrained on 210,035 image-text pairs for plane classification, biometry, and segmentation.

    Imaging
    13Openness