All Competitors
Every biological foundation model, evaluated and ranked by the bio.rodeo team
Showing 97–120 of 316 filtered models
SEAL
484—Vision-omics finetuning that aligns pathology foundation models with spatial transcriptomics so morphology features predict local gene expression.
PathologySpatial omics32OpennessProtein language model that encodes sequences as discrete words from a learned vocabulary for zero-shot function inference and protein design.
Protein24OpennessdnaHNet
—2—Tokenizer-free genomic foundation model that adaptively chunks raw nucleotides, enabling zero-shot variant fitness and gene essentiality prediction.
DNA & Gene12OpennessARSENAL
16——Masked DNA language model for regulatory genomics with a motif-discovery regularizer for zero-shot TF motif recovery and variant effect prediction.
DNA & Gene29OpennessDecoderTCR
8——Masked language model for T-cell receptor and peptide-MHC binding prediction, with compositional pretraining and non-autoregressive decoding.
Protein56OpennessNUWA
———mRNA language foundation model trained on ~115M protein-coding sequences across the tree of life, unifying mRNA perception and generation.
RNADNA & Gene16OpennessEchoJEPA
3294—Joint-embedding predictive foundation model for echocardiography, pretrained on 18M cardiac ultrasound videos for artifact-robust representations.
Imaging62OpennessevoRate
———Genome language model that adds evolutionary-rate prediction to pretraining, improving representations for variant effect and regulatory genomics.
DNA & Gene14OpennessFoldVision
———Structure-based protein encoder that voxelizes every heavy atom into a 3D grid, learning orientation-robust representations for protein function.
Protein20OpennessProtProfileMD
363—LoRA adapter on ProstT5 predicting per-residue distributions over Foldseek 3Di tokens, capturing conformational flexibility from MD trajectories.
Protein93OpennessSAGE-FM
———Spatial transcriptomics foundation model built on a lightweight graph convolutional network and trained by masked central-spot prediction.
Spatial omicsSingle-cell10OpennessPathDiffusion
151—Evolution-guided diffusion model that generates temporal protein folding pathways, from unfolded chain to native state, rather than static structures.
Protein64OpennessGluFormer
8719—Weizmann Institute of Science +2 othersJanuary 14, 2026continuous_glucose_monitoringfoundation_modelgenerative+6Generative transformer foundation model for continuous glucose monitoring, forecasting glycemia and stratifying health risk from raw glucose traces.
Biosignals60OpennessSTACK
14211—Single-cell foundation model using tabular attention over context cells to predict responses to arbitrary perturbations without fine-tuning.
Single-cell33OpennessDNAChunker
—1—Masked DNA language model with a learnable, adaptive tokenizer that produces context-dependent, variable-length segments instead of fixed k-mers.
DNA & Gene23OpennessBiomeGPT
—1—Massachusetts General HospitalJanuary 5, 2026biomarker_discoverydisease_classificationfoundation_model+6Gut microbiome foundation model pretrained on human shotgun metagenomes, learning species-level taxonomic representations for disease prediction.
DNA & GeneLanguage model8OpennessNetMedGPT
—2—Transformer foundation model pretrained on a biomedical knowledge graph for zero-shot drug repurposing, target, and adverse-effect prediction.
Language modelSmall molecule24OpennessSpatialDINO
—1—Native 3D vision transformer self-supervised on unlabeled fluorescence microscopy volumes, segmenting subcellular structures without voxel labels.
Imaging8OpennessOmniCell
—1—Transcriptomic foundation model pretrained on 67M single-cell and spatial profiles, modeling gene expression and inter-cellular dependencies.
Single-cellSpatial omics9OpennessMicroGenomer
10——470M-parameter microbial genome foundation model trained on 234.5B base pairs for multi-scale genomic representation and trait prediction.
DNA & Gene44OpennessHELM-BERT
14—471Peptide language model trained on HELM notation, a DeBERTa encoder for property prediction on macrocyclic and non-canonical medium-sized peptides.
Small molecule80OpennessSpatially aware transcriptomic foundation models for cancer, pairing 50um-Local and 250um-Extended views of spot-resolution spatial transcriptomes.
Spatial omics12OpennessM-Optimus
———Multimodal foundation model that embeds histology, transcriptomics, and clinical records in one space for patient stratification and target discovery.
PathologySpatial omicsSingle-cell3OpennessGlycanGT
3——Graph transformer foundation model for glycans, learning reusable embeddings of branched carbohydrate structures for glycomics prediction tasks.
Small molecule82Openness